Research output per year
Research output per year
Personal profile
Research
Aneuploidy in malignancies
Aberrant chromosome numbers – i.e. aneuploidy – is one of the most common characteristics of malignant cells. The overall aim of my research is to understand how aneuploidy arises in somatic cells, how it affects tumorigenesis, and how it correlates with prognosis and treatment response. In particular, my studies are focused on high hyperdiploid and hypodiploid childhood acute lymphoblastic leukemia. Ultimately, the goal is to use the new knowledge that we gain from these studies of the basis of tumorigenesis to improve the survival of cancer patients.
Professional work
Dr Paulsson is Professor of Medical Genetics and runs the Aneuploidy in Cancer research group at the Division of Clinical Genetics. She is an expert in cancer genomics and is experienced in classic genetic techniques such as chromosome analysis and fluorescence in situ hybridization as well as state-of-the-art SNP array analysis and next generation sequencing (NGS).
UKÄ subject classification
- Cancer and Oncology
Free keywords
- aneuploidy
- hyperdiploidy
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia
Woodward, E. L., Yang, M., Moura-Castro, L. H., van den Bos, H., Gunnarsson, R., Olsson-Arvidsson, L., Spierings, D. C. J., Castor, A., Duployez, N., Zaliova, M., Zuna, J., Johansson, B., Foijer, F. & Paulsson, K., 2023 Mar 25, In: Nature Communications. 14, 1658.Research output: Contribution to journal › Article › peer-review
Open Access -
13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking
Yang, M., Safavi, S., Woodward, E. L., Duployez, N., Olsson-arvidsson, L., Ungerbäck, J., Sigvardsson, M., Zaliova, M., Zuna, J., Fioretos, T., Johansson, B., Nord, K. H. & Paulsson, K., 2020 Aug 20, In: Blood. 136, 8, p. 946-956 11 p.Research output: Contribution to journal › Article › peer-review
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Proteogenomics and Hi-C reveal transcriptional dysregulation in high hyperdiploid childhood acute lymphoblastic leukemia
Yang, M., Vesterlund, M., Siavelis, I., Moura-Castro, L. H., Castor, A., Fioretos, T., Jafari, R., Lilljebjörn, H., Odom, D. T., Olsson, L., Ravi, N., Woodward, E. L., Harewood, L., Lehtiö, J. & Paulsson, K., 2019 Apr 3, In: Nature Communications. 10, 1, 1519.Research output: Contribution to journal › Article › peer-review
Open Access -
Outcome of Children With Hypodiploid Acute Lymphoblastic Leukemia: A Retrospective Multinational Study
Paulsson, K. & Ponte di Legno Childhood ALL Working Group, 2019 Apr 1, In: Journal of Clinical Oncology. 37, 10, p. 770-779 10 p.Research output: Contribution to journal › Article › peer-review
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The genomic landscape of high hyperdiploid childhood acute lymphoblastic leukemia.
Paulsson, K., Lilljebjörn, H., Biloglav, A., Olsson, L., Rissler, M., Castor, A., Barbany, G., Fogelstrand, L., Nordgren, A., Sjögren, H., Fioretos, T. & Johansson, B., 2015, In: Nature Genetics. 47, 6, p. 672-676Research output: Contribution to journal › Article › peer-review
File477 Downloads (Pure)
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Non-coding mutations in pediatric acute lymphoblastic leukemia
Aydin, E., Paulsson, K. & Yang, M.
2021/10/01 → 2025/10/01
Project: Dissertation
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Epigenetics - Theme, Pufendorf IAS
Forsén, S., Castor, A., Bengtsson, T., Brosberg, K., Hedlund, M., Höglund, M., Lindvall, M., Ling, C., Minssen, T., Paulsson, K., Psouni, E., Ringnér, M. & Bommenel, E.
2009/08/09 → 2010/08/10
Project: Network
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6th Swedish Cancer Research Meeting
Göran B Jönsson (Keynote/plenary speaker), Thoas Fioretos (Keynote/plenary speaker), Sophia Zackrisson (Chair), Yvonne Ceder (Chair), Evangelia Sereti (Session chair), Kajsa Paulsson (Speaker), Anna Sandström Gerdtsson (Speaker), Alexander Pietras (Speaker), Sophie Lehn (Session chair), Ervin Ascic (Speaker), Johann de Bono (Keynote/plenary speaker), Daniel Öhlund (Keynote/plenary speaker), luiz diaz (Keynote/plenary speaker), Anna Martner (Keynote/plenary speaker), Gunilla Enblad (Keynote/plenary speaker), Laura J. Esserman (Keynote/plenary speaker), Olli Kallioniemi (Keynote/plenary speaker) & Regina Beets-Tan (Keynote/plenary speaker)
2023 May 16 → 2023 May 17Activity: Participating in or organising an event › Organisation of conference
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Lund University Cancer Centre (LUCC) meeting
Pia Berntsson (Member of programme committee), Sophia Zackrisson (Member of programme committee), Mef Nilbert (Member of programme committee), Vinay Swaminathan (Member of programme committee), Anna Martling (Invited speaker), Ron M.A. Heeren (Invited speaker), David Gisselsson Nord (Speaker), Cristian Bellodi (Speaker), Sergio Mosquim Junior (Speaker), Natalie Andersson (Speaker), Kelin Gonçalves de Oliveira (Speaker), Selamawit Mekuria (Speaker), Teo Helkkula (Speaker), Christopher Godina (Speaker), Lars E Olsson (Speaker), Kristina Lång (Speaker), Helena Ågerstam (Speaker), Axel Hyrenius Wittsten (Speaker), Paul Bourgine (Speaker), Maria Alvarado Kristensson (Speaker), Ana Carneiro (Speaker), Helena Jernström (Speaker), Annika Malmborg Kisch (Speaker), Marlene Malmström (Speaker), Anna-Maria Larsson (Speaker), Sophia Zackrisson (Session chair), Kajsa Paulsson (Session chair), Kees-Jan Pronk (Session chair), Vinay Swaminathan (Session chair), Ingrid Hedenfalk (Session chair), Ramin Massoumi (Session chair), Ida Dalene Skarping (Session chair), Karin Leandersson (Session chair), Anna Sandström Gerdtsson (Session chair), Marcus Järås (Session chair), Ana Carneiro (Session chair), Tanja Stocks (Session chair), Annika Malmborg Kisch (Session chair) & Marlene Malmström (Session chair)
2023 May 4Activity: Participating in or organising an event › Organisation of conference
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LUCC - Child: Acute Lymphoblastic Leukemia (ALL) - Seminar
Daniel Bexell (Organiser), Kees-Jan Pronk (Organiser), Anders Castor (Speaker) & Kajsa Paulsson (Speaker)
2021 Apr 29Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
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Focus on Cancer collaboration
Cecilia Jädert (Organiser), Anna-Karin Wihlborg (Invited speaker), Carina Bernardo (Organiser), Corinna Richter (Organiser), Chris Madsen (Organiser), Douglas Hanahan (Invited speaker), Åsa Dahm (Invited speaker), Göran Ahlgren (Invited speaker), Trine Grönlund (Invited speaker), Anders Bjartell (Invited speaker), Bjorn Walse (Invited speaker), Kajsa Paulsson (Session chair), Emma Niméus (Session chair), Pamela Buchwald (Session chair), Roland Andersson (Session chair), Marcus Järås (Session chair), Ana Carneiro (Session chair), Håkan Axelson (Session chair), Gottfrid Sjödahl (Session chair) & Pia Berntsson (Advisor)
2021 Feb 4Activity: Participating in or organising an event › Organisation of conference
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Lund University Cancer Centre (LUCC) Kick-off meeting
Kristian Pietras (Member of programme committee), Mikael Sigvardsson (Member of programme committee), Mats Jerkeman (Member of programme committee), Ingrid Hedenfalk (Member of programme committee), Karin Jirström (Member of programme committee), Karin Leandersson (Member of programme committee), Thoas Fioretos (Member of programme committee), Pia Berntsson (Member of programme committee), Klas Kärre (Invited speaker), Erik Renström (Speaker), Kristian Pietras (Speaker), Leena Liljedahl (Speaker), DANIEL ANSARI (Speaker), Lao Saal (Speaker), Ana Bosch Campos (Speaker), Anna Hagström-Andersson (Speaker), Stefan Scheding (Speaker), Daniel Bexell (Speaker), Håkan Axelson (Speaker), Alexander Pietras (Speaker), Mattias Belting (Speaker), Göran B Jönsson (Speaker), Karolin Isaksson (Speaker), Maria Planck (Speaker), Kajsa Paulsson (Speaker), Sophia Zackrisson (Speaker), Malin Lindstedt (Speaker) & Ana Carneiro (Speaker)
2020 Feb 4Activity: Participating in or organising an event › Organisation of conference
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Prizes and Distinction
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Samfundet Folkhälsan Albert de la Chapelle Prize in Medical Genetics
Paulsson, Kajsa (Recipient), 2022
Prize: Prize (including medals and awards)
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Senior Investigator Award, Cancerfonden
Paulsson, Kajsa (Recipient), 2015
Prize: Prize (including medals and awards)