Research output per year
Research output per year
Personal profile
Research
Karin Jirström is a professor and senior consultant in pathology. She has longstanding experience in tumour-agnostic cancer biomarker research, and her laboratory harbours a wide range of tissue microarrays with retrospectively collected, clinically well-annotated tumours representing several types of major solid cancers. She is now following up with prospective clinical on-treatment biomarker studies. In these studies, the spatial molecular heterogeneity in resected primary tumours and metastases is being comprehensively mapped, and blood samples are collected during systemic treatment to study the temporal heterogeneity and clonal evolution of tumours.
UKÄ subject classification
- Cancer and Oncology
Keywords
- Cancer biomarkers
- Pancreatic cancer
- Colorectal cancer
- Clinical studies
- Tumour evolution
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Research output
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An immune score reflecting pro- and anti-tumoural balance of tumour microenvironment has major prognostic impact and predicts immunotherapy response in solid cancers
Mezheyeuski, A., Backman, M., Mattsson, J., Martín-Bernabé, A., Larsson, C., Hrynchyk, I., Hammarström, K., Ström, S., Ekström, J., Mauchanski, S., Khelashvili, S., Lindberg, A., Agnarsdóttir, M., Edqvist, P. H., Huvila, J., Segersten, U., Malmström, P-U., Botling, J., Nodin, B., Hedner, C., & 10 others, 2023, In: EBioMedicine. 88, p. 1-18 104452.Research output: Contribution to journal › Article › peer-review
Open Access -
Expression of Cartilage Oligomeric Matrix Protein in colorectal cancer is an adverse prognostic factor and correlates negatively with infiltrating immune cells and PD-L1 expression
Blom, A. M., Gialeli, C., Hagerling, C., Berntsson, J., Jirström, K. & Papadakos, K. S., 2023, In: Frontiers in Immunology. 14, 1167659.Research output: Contribution to journal › Article › peer-review
Open Access -
Imaging ovarian cancer - from baseline characteristics to high-risk image factors
Sartor, H., Bjurberg, M., Asp, M., Kahn, A., Brändstedt, J., Kannisto, P. & Jirström, K., 2023 Apr 17, In: Journal of Ovarian Research. 16, 1, 78.Research output: Contribution to journal › Article › peer-review
Open Access -
Sex and gender differences in treatment intention, quality of life and performance status in the first 100 patients with periampullary cancer enrolled in the CHAMP study
Olsson Hau, S., Williamsson, C., Andersson, B., Eberhard, J. & Jirström, K., 2023 Apr 11, In: BMC Cancer. 23, 1, 334.Research output: Contribution to journal › Article › peer-review
Open Access -
Spatial immunophenotyping of the tumour microenvironment in non-small cell lung cancer
Backman, M., Strell, C., Lindberg, A., Mattsson, J. S. M., Elfving, H., Brunnström, H., O'Reilly, A., Bosic, M., Gulyas, M., Isaksson, J., Botling, J., Kärre, K., Jirström, K., Lamberg, K., Pontén, F., Leandersson, K., Mezheyeuski, A. & Micke, P., 2023, In: European Journal of Cancer. 185, p. 40-52Research output: Contribution to journal › Article › peer-review
Open Access
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Delineating the local and systemic immune responses during pancreatic cancer evolution
Svensson, M., Jirström, K. & Jönsson, G. B.
2022/01/01 → 2026/01/01
Project: Dissertation
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Chemotherapy, Host response And Molecular dynamics in Periampullary cancer
Jirström, K., Leandersson, K., Heby, M., Olsson Hau, S., Eberhard, J., Nodin, B., Svensson, M. & Petersson, A.
Sjöbergstiftelsen, Lennart Glans Stiftelse, Cancerfonden, Swedish Research Council, Fru Berta Kamprads stiftelse för utforskning och bekämpning av cancersjukdomar
2018/09/01 → …
Project: Research
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Prognostiska markörer vid Kolorektal cancer
Nobin, H., Brunnström, H. & Jirström, K.
2017/05/02 → …
Project: Dissertation
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Histopathological and molecular diagnostics of lung cancer
Brunnström, H., Malmros, K., Blackö, A., Staaf, J., Planck, M., Jirström, K., Micke, P. & Botling, J.
Fru Berta Kamprads stiftelse för utforskning och bekämpning av cancersjukdomar, Cancerfonden, Gunnar Nilssons cancerstiftelse
2011/08/15 → …
Project: Research
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Sex, hormonal factors and pancreatic cancer
Andersson, G., Jirström, K. & Borgquist, S.
2016/03/01 → 2019/05/17
Project: Dissertation
Activities
- 1 Organisation of conference
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Lund University Cancer Centre (LUCC) Kick-off meeting
Kristian Pietras (Member of programme committee), Mikael Sigvardsson (Member of programme committee), Mats Jerkeman (Member of programme committee), Ingrid Hedenfalk (Member of programme committee), Karin Jirström (Member of programme committee), Karin Leandersson (Member of programme committee), Thoas Fioretos (Member of programme committee), Pia Berntsson (Member of programme committee), Klas Kärre (Invited speaker), Erik Renström (Speaker), Kristian Pietras (Speaker), Leena Liljedahl (Speaker), DANIEL ANSARI (Speaker), Lao Saal (Speaker), Ana Bosch Campos (Speaker), Anna Hagström-Andersson (Speaker), Stefan Scheding (Speaker), Daniel Bexell (Speaker), Håkan Axelson (Speaker), Alexander Pietras (Speaker), Mattias Belting (Speaker), Göran B Jönsson (Speaker), Karolin Isaksson (Speaker), Maria Planck (Speaker), Kajsa Paulsson (Speaker), Sophia Zackrisson (Speaker), Malin Lindstedt (Speaker) & Ana Carneiro (Speaker)
2020 Feb 4Activity: Participating in or organising an event › Organisation of conference
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Infrastructure
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HistoCore Facility
Karin Jirström (Manager) & Björn Nodin (Manager)
Therapeutic pathologyInfrastructure