The pathologist´s role is to deliver accurate diagnosis of disease, so as to enable optimaltreatment strategies for individual patients. In the wake of the ’omics revolution, with anincreasing availability and impact of a wide range of molecular technologies, clinicalpathology is currently undergoing a paradigm shift. However, despite the clear value ofthese technologies in further refining the diagnostic accuracy and paving the way forpersonalized medicine, the greatest current challenge is to decipher and reduce the vastamount of information into clinically relevant and applicable assays.
The overarching aim of my research is to identify and validate tissue biomarkers forimproved prognostication and response prediction in several major types of cancer. Inaddition, we study the influence of genetic, anthropometric and lifestyle-related factorson cancer development and progression. To this end, we utilize a unique researchplatform with tumours from incident cancer cases in the large, prospective population-based cohorts Malmö Diet and Cancer and Malmö Preventive Project