Research output per year
Research output per year
Search results
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2025
The superantigen SEA binds to human γδ T cell receptor and activates γδ T cells with moderate MHC class II dependence
Uzunçayır, S., Petruk, G., Mata Forsberg, M., Arasa, C., Sverremark-Ekström, E. & Lindkvist-Petersson, K., 2025 May, In: Molecular Immunology. 181, p. 1-8 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2024
SMS121, a new inhibitor of CD36, impairs fatty acid uptake and viability of acute myeloid leukemia
Åbacka, H., Masoni, S., Poli, G., Huang, P., Gusso, F., Granchi, C., Minutolo, F., Tuccinardi, T., Hagström-Andersson, A. K. & Lindkvist-Petersson, K., 2024 Dec, In: Scientific Reports. 14, 1, 9104.Research output: Contribution to journal › Article › peer-review
Open Access -
The structure and function of P5A-ATPases
Li, P., Bågenholm, V., Hägglund, P., Lindkvist-Petersson, K., Wang, K. & Gourdon, P., 2024 Dec, In: Nature Communications. 15, 1, 9605.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular basis for human aquaporin inhibition
Huang, P., Åbacka, H., Wilson, C. J., Wind, M. L., Rűtzler, M., Hagström-Andersson, A., Gourdon, P., de Groot, B. L., Venskutonytė, R. & Lindkvist-Petersson, K., 2024 Feb 6, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 7, 8 p., e2319682121.Research output: Contribution to journal › Article › peer-review
Open Access -
Closed and open structures of the eukaryotic magnesium channel Mrs2 reveal the auto-ligand-gating regulation mechanism
Li, P., Liu, S., Wallerstein, J., Villones, R. L. E., Huang, P., Lindkvist-Petersson, K., Meloni, G., Lu, K., Steen Jensen, K., Liin, S. I. & Gourdon, P., 2024, (Accepted/In press) In: Nature Structural and Molecular Biology.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Principles to recover copper-conducting CTR proteins for the purpose of structural and functional studies
Nayeri, N., Li, P., Górecki, K., Lindkvist-Petersson, K. & Gourdon, P., 2023 Mar, In: Protein Expression and Purification. 203, 106213.Research output: Contribution to journal › Article › peer-review
Open Access -
Cryo-EM structure supports a role of AQP7 as a junction protein
Huang, P., Venskutonytė, R., Prasad, R. B., Ardalani, H., de Maré, S. W., Fan, X., Li, P., Spégel, P., Yan, N., Gourdon, P., Artner, I. & Lindkvist-Petersson, K., 2023, In: Nature Communications. 14, p. 1-12 600.Research output: Contribution to journal › Article › peer-review
Open Access -
The intracellular helical bundle of human glucose transporter GLUT4 is important for complex formation with ASPL
Huang, P., Åbacka, H., Varela, D., Venskutonytė, R., Happonen, L., Bogan, J. S., Gourdon, P., Amiry-Moghaddam, M. R., André, I. & Lindkvist-Petersson, K., 2023, In: FEBS Open Bio. 13, 11, p. 2094-2107Research output: Contribution to journal › Article › peer-review
Open Access -
The structure of songbird MHC class I reveals antigen binding that is flexible at the N-terminus and static at the C-terminus
Eltschkner, S., Mellinger, S., Buus, S., Nielsen, M., Paulsson, K. M., Lindkvist-Petersson, K. & Westerdahl, H., 2023, In: Frontiers in Immunology. 14, 14 p., 1209059.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Structures of Atm1 provide insight into [2Fe-2S] cluster export from mitochondria
Li, P., Hendricks, A. L., Wang, Y., Villones, R. L. E., Lindkvist-Petersson, K., Meloni, G., Cowan, J. A., Wang, K. & Gourdon, P., 2022 Dec, In: Nature Communications. 13, 1, 4339.Research output: Contribution to journal › Article › peer-review
Open Access -
Microfluidic-Derived Detection of Protein-Facilitated Copper Flux Across Lipid Membranes
Górecki, K., Hansen, J. S., Li, P., Nayeri, N., Lindkvist-Petersson, K. & Gourdon, P., 2022 Aug 30, In: Analytical Chemistry. 94, 34, p. 11831-11837 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
PcoB is a defense outer membrane protein that facilitates cellular uptake of copper
Li, P., Nayeri, N., Górecki, K., Becares, E. R., Wang, K., Mahato, D. R., Andersson, M., Abeyrathna, S. S., Lindkvist-Petersson, K., Meloni, G., Missel, J. W. & Gourdon, P., 2022 Jul, In: Protein Science. 31, 7, e4364.Research output: Contribution to journal › Article › peer-review
Open Access -
Aquaglyceroporins and orthodox aquaporins in human adipocytes
Huang, P., Hansen, J. S., Saba, K. H., Bergman, A., Negoita, F., Gourdon, P., Hagström-Andersson, A. & Lindkvist-Petersson, K., 2022 Feb 1, In: Biochimica et Biophysica Acta - Biomembranes. 1864, 1, 183795.Research output: Contribution to journal › Article › peer-review
Open Access -
Activation of human γδ T cells and NK cells by Staphylococcal enterotoxins requires both monocytes and conventional T cells
Mata Forsberg, M., Arasa, C., van Zwol, W., Uzunçayir, S., Schönbichler, A., Regenthal, P., Schelin, J., Lindkvist-Petersson, K., Björkander, S. & Sverremark-Ekström, E., 2022, In: Journal of Leukocyte Biology. 111, 3, p. 597-609Research output: Contribution to journal › Article › peer-review
Open Access -
Analyses of the complex formation of staphylococcal enterotoxin A and the human gp130 cytokine receptor
Uzuncayir, S., Vera-Rodriguez, A., Regenthal, P., Åbacka, H., Emanuelsson, C., Bahl, C. D. & Lindkvist-Petersson, K., 2022, In: FEBS Letters. 596, 7, p. 910-923Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Structural characterization of the microbial enzyme urocanate reductase mediating imidazole propionate production
Venskutonytė, R., Koh, A., Stenström, O., Khan, M. T., Lundqvist, A., Akke, M., Bäckhed, F. & Lindkvist-Petersson, K., 2021, In: Nature Communications. 12, 1, p. 1347Research output: Contribution to journal › Article › peer-review
Open Access -
Targeting GLUT1 in acute myeloid leukemia to overcome cytarabine resistance
Åbacka, H., Hansen, J. S., Huang, P., Venskutonytė, R., Hyrenius-Wittsten, A., Poli, G., Tuccinardi, T., Granchi, C., Minutolo, F., Hagström-Andersson, A. K. & Lindkvist-Petersson, K., 2021, In: Haematologica. 106, 4, p. 1163-1166Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Peptide-Oleate Complexes Create Novel Membrane-Bound Compartments
Hansen, J. S., Tran, T. H., Cavalera, M., Paul, S., Chaudhuri, A., Lindkvist-Petersson, K., Ho, J. C. S. & Svanborg, C., 2020 Nov 1, In: Molecular biology and evolution. 37, 11, p. 3083-3093 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural Basis for Glycerol Efflux and Selectivity of Human Aquaporin 7
de Maré, S. W., Venskutonytė, R., Eltschkner, S., de Groot, B. L. & Lindkvist-Petersson, K., 2020 Feb 4, In: Structure. 28, 2, p. 215-222.e3Research output: Contribution to journal › Article › peer-review
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2018
De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia
Hyrenius-Wittsten, A., Pilheden, M., Sturesson, H., Hansson, J., Walsh, M. P., Song, G., Kazi, J. U., Liu, J., Ramakrishan, R., Garcia-Ruiz, C., Nance, S., Gupta, P., Zhang, J., Rönnstrand, L., Hultquist, A., Downing, J. R., Lindkvist-Petersson, K., Paulsson, K., Järås, M. & Gruber, T. A. & 2 others, , 2018 Dec 1, In: Nature Communications. 9, 1, 1770.Research output: Contribution to journal › Article › peer-review
Open Access -
Protein Engineering Allows for Mild Affinity-based Elution of Therapeutic Antibodies
Kanje, S., Venskutonytė, R., Scheffel, J., Nilvebrant, J., Lindkvist-Petersson, K. & Hober, S., 2018, In: Journal of Molecular Biology. 430, 18, p. 3427-3438Research output: Contribution to journal › Article › peer-review
Open Access -
2017
Quantification of the Intracellular Life Time of Water Molecules to Measure Transport Rates of Human Aquaglyceroporins
Palmgren, M., Hernebring, M., Eriksson, S., Elbing, K., Geijer, C., Lasič, S., Dahl, P., Söndergaard Hansen, J., Topgaard, D. & Lindkvist-Petersson, K., 2017 Dec, In: Journal of Membrane Biology. 250, 6, p. 629-639Research output: Contribution to journal › Article › peer-review
Open Access -
Visualization of lipid directed dynamics of perilipin 1 in human primary adipocytes
Hansen, J. S., De Maré, S., Jones, H. A., Göransson, O. & Lindkvist-Petersson, K., 2017 Nov 8, In: Scientific Reports. 7, 1, 15011.Research output: Contribution to journal › Article › peer-review
Open Access -
NMR quantification of diffusional exchange in cell suspensions with relaxation rate differences between intra and extracellular compartments
Eriksson, S., Elbing, K., Söderman, O., Lindkvist-Petersson, K., Topgaard, D. & Lasič, S., 2017 May 1, In: PLoS ONE. 12, 5, e0177273.Research output: Contribution to journal › Article › peer-review
Open Access -
Frequent low-level mutations of Protein Kinase D2 in angiolipoma
Hofvander, J., Arbajian, E., G Stenkula, K., Lindkvist-Petersson, K., Larsson, M., Nilsson, J., Magnusson, L., von Steyern, F. V., Rissler, P., L Hornick, J. & Mertens, F., 2017, In: Journal of Pathology. 241, 5, p. 578-582Research output: Contribution to journal › Article › peer-review
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Thermal stability and structural changes in bacterial toxins responsible for food poisoning
Regenthal, P., Söndergaard Hansen, J., André, I. & Lindkvist-Petersson, K., 2017, In: PLoS ONE. 12, 2, e0172445.Research output: Contribution to journal › Article › peer-review
Open Access -
2016
Branched short-chain fatty acids modulate glucose and lipid metabolism in primary adipocytes
Heimann, E., Nyman, M., Holmén-Pålbrink, A.-K., Lindkvist-Petersson, K. & Degerman, E., 2016 Dec 21, In: Adipocyte. 5, 4, p. 359-368Research output: Contribution to journal › Article › peer-review
Open Access -
Perilipin 1 binds to aquaporin 7 in human adipocytes and controls its mobility via protein kinase A mediated phosphorylation
Söndergaard Hansen, J., Krintel, C., Hernebring, M., Haataja, T. J. K., de Marè, S., Wasserstrom, S., Kosinska-Eriksson, U., Palmgren, M., Holm, C., Stenkula, K. G., Jones, H. A. & Lindkvist-Petersson, K., 2016 Dec 1, In: Metabolism, Clinical and Experimental. 65, 12, p. 1731-1742 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Two common structural motifs for TCR recognition by staphylococcal enterotoxins
Rödström, K. E. J., Regenthal, P., Bahl, C., Ford, A., Baker, D. & Lindkvist-Petersson, K., 2016 May 16, In: Scientific Reports. 6Research output: Contribution to journal › Article › peer-review
Open Access -
Crystallization and Structure Determination of Superantigens and Immune Receptor Complexes.
Rödström, K. & Lindkvist, K., 2016, In: Methods in Molecular Biology. 1396, p. 51-65Research output: Contribution to journal › Article › peer-review
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2015
Glucose transport machinery reconstituted in cell models.
Söndergaard Hansen, J., Elbing, K., Thompson, J. R., Malmstadt, N. & Lindkvist, K., 2015, In: Chemical Communications. 51, 12, p. 2316-2319Research output: Contribution to journal › Article › peer-review
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Structure of Staphylococcal Enterotoxin E in Complex with TCR Defines the Role of TCR Loop Positioning in Superantigen Recognition.
Rödström, K., Regenthal, P. & Lindkvist, K., 2015, In: PLoS ONE. 10, 7, e0131988.Research output: Contribution to journal › Article › peer-review
Open Access -
2014
Structure of the Superantigen Staphylococcal Enterotoxin B in Complex with TCR and Peptide-MHC Demonstrates Absence of TCR-Peptide Contacts.
Rödström, K., Elbing, K. & Lindkvist, K., 2014, In: Journal of Immunology. 193, 4, p. 1998-2004Research output: Contribution to journal › Article › peer-review
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Superantigen activates the gp130 receptor on adipocytes resulting in altered adipocyte metabolism.
Banke, E., Rödström, K., Ekelund, M., Dalla-Riva, J., Lagerstedt, J., Nilsson, S., Degerman, E., Lindkvist, K. & Nilson, B., 2014, In: Metabolism, Clinical and Experimental. 63, 6, p. 831-840Research output: Contribution to journal › Article › peer-review
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2013
The Tumor Targeted Superantigen ABR-217620 Selectively Engages TRBV7-9 and Exploits TCR-pMHC Affinity Mimicry in Mediating T Cell Cytotoxicity.
Hedlund, G., Eriksson, H., Sundstedt, A., Forsberg, G., Jakobsen, B. K., Pumphrey, N., Rödström, K., Lindkvist, K. & Björk, P., 2013, In: PLoS ONE. 8, 10, e79082.Research output: Contribution to journal › Article › peer-review
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2012
Yeast Aquaglyceroporins Use the Transmembrane Core to Restrict Glycerol Transport
Geijer, C., Ahmadpour, D., Palmgren, M., Filipsson, C., Klein, D. M., Tamas, M. J., Hohmann, S. & Lindkvist, K., 2012, In: Journal of Biological Chemistry. 287, 28, p. 23562-23570Research output: Contribution to journal › Article › peer-review
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2010
Backbone resonance assignment of Staphylococcal Enterotoxin H
Saline, M., Orekhov, V. Y., Lindkvist-Petersson, K. & Karlsson, B. G., 2010 Apr, In: Biomolecular NMR Assignments. 4, 1, p. 1-4Research output: Contribution to journal › Article › peer-review
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The structure of superantigen complexed with TCR and MHC reveals novel insights into superantigenic T cell activation
Saline, M., Rodstrom, K. E. J., Fischer, G., Orekhov, V. Y., Karlsson, B. G. & Lindkvist, K., 2010, In: Nature Communications. 1, 119.Research output: Contribution to journal › Article › peer-review
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2009
Crystal structure of a yeast aquaporin at 1.15 Å reveals a novel gating mechanism
Fischer, G., Kosinska-Eriksson, U., Aponte-Santamaría, C., Palmgren, M., Geijer, C., Hedfalk, K., Hohmann, S., de Groot, B. L., Neutze, R. & Lindkvist-Petersson, K., 2009 Jun, In: PLoS Biology. 7, 6, p. 1-13 e1000130.Research output: Contribution to journal › Article › peer-review
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2008
Affinity tags can reduce merohedral twinning of membrane protein crystals
Backmark, A., Nyblom, M., Tornroth-Horsefield, S., Kosinska-Eriksson, U., Nordén, K., Agemark, M., Kjellbom, P., Johanson, U., Hedfalk, K., Lindkvist- ersson, K., Neutze, R. & Horsefield, R., 2008, In: Acta Crystallographica. Section D: Biological Crystallography. 64, p. 1183-1186Research output: Contribution to journal › Article › peer-review
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2007
Exceptional overproduction of a functional human membrane protein
Nyblom, M., Öberg, F., Lindkvist-Petersson, K., Hallgren, K., Findlay, H., Wikström, J., Karlsson, A., Hansson, Ö., Booth, P. J., Bill, R. M., Neutze, R. & Hedfalk, K., 2007 Nov, In: Protein Expression and Purification. 56, 1, p. 110-120 11 p.Research output: Contribution to journal › Article › peer-review
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Cutting edge: Evidence of direct TCR α-chain interaction with superantigen
Pumphrey, N., Vuidepot, A., Jakobsen, B. K., Forsberg, G., Walse, B. & Lindkvist-Petersson, K., 2007 Sept 1, In: Journal of Immunology. 179, 5, p. 2700-2704Research output: Contribution to journal › Article › peer-review
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2005
High-level bacterial secretion of single-chain αβ T-cell receptors
Maynard, J., Adams, E. J., Krogsgaard, M., Lindkvist, K., Liu, C. W. & Garcia, K. C., 2005 Nov 30, In: Journal of Immunological Methods. 306, 1-2, p. 51-67 17 p.Research output: Contribution to journal › Article › peer-review
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Structure of an autoimmune T cell receptor complexed with class II peptide-MHC: Insights into MHC bias and antigen specificity
Maynard, J., Lindkvist, K., Wilson, D. H., Adams, E. J., Blondelle, S. E., Boulanger, M. J., Wilson, D. B. & Garcia, K. C., 2005 Jan, In: Immunity. 22, 1, p. 81-92 12 p.Research output: Contribution to journal › Article › peer-review
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Dental pulp capping: effect of Emdogain Gel on experimentally exposed human pulps.
Olsson, H., Davies, J. R., Holst, K. E., Schröder, U. & Lindkvist, K., 2005, In: International Endodontic Journal. 38, 3, p. 186-94Research output: Contribution to journal › Article › peer-review
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2003
Spectrophotometric methods for the determination of superantigen structure and stability.
Cavallin, A., Lindkvist, K. & Forsberg, G., 2003, In: Methods in Molecular Biology. 214, p. 55-63Research output: Contribution to journal › Article › peer-review
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Staphylococcal enterotoxin H induces V alpha-specific expansion of T cells.
Lindkvist, K., Pettersson, H., Skartved, N. J., Walse, B. & Forsberg, G., 2003, In: Journal of Immunology. 170, 8, p. 4148-4154Research output: Contribution to journal › Article › peer-review
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2002
Crystal structure of a SEA variant in complex with MHC class II reveals the ability of SEA to crosslink MHC molecules
Lindkvist, K., Thunnissen, M., Forsberg, G. & Walse, B., 2002, In: Structure. 10, 12, p. 1619-1626Research output: Contribution to journal › Article › peer-review
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2001
Crystal structure of a superantigen bound to MHC class II displays zinc and peptide dependence
Petersson, K., Håkansson, M., Nilsson, H., Forsberg, G., Svensson, L. A., Liljas, A. & Walse, B., 2001 Jul 2, In: EMBO Journal. 20, 13, p. 3306-3312 7 p.Research output: Contribution to journal › Article › peer-review
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2000
The crystal structure of staphylococcal enterotoxin H: Implications for binding properties to MHC class II and TcR molecules
Håkansson, M., Lindkvist, K., Nilsson, H., Forsberg, G., Björk, P., Antonsson, P. & Svensson, L., 2000 Sept 22, In: Journal of Molecular Biology. 302, 3, p. 527-537 11 p.Research output: Contribution to journal › Article › peer-review