Research output per year
Research output per year
Personal profile
Research
My research focuses on Huntington´s disease and peripheral disease manifestations, how these affects brain pathology, how these could translate into biomarker possibilities and how these could potentially lead to therapeutic avenues.
The neurodegenerative disease, Huntington’s disease, is caused by a mutation in the gene that codes for the protein huntingtin. Huntingtin is expressed throughout the whole body.
My overarching hypothesis is that effects of mutant huntingtin within peripheral cells and tissue, mirror neuronal pathology and therefore peripheral manifestations can be a tool to model disease. We aim to identify disease related dysfunction in Huntington´s disease in order to find biomarkers of patholgogical processes and new therapeutic strategies.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Subject classification (UKÄ)
- Medical and Health Sciences
- Basic Medicine
- Pharmacology and Toxicology
- Neurosciences
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Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
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Centrally and peripherally altered glucose transporters: is it time to revisit energy deficiency as a potential treatment strategy in Huntington's disease?
Björkqvist, M., 2023 Dec, In: EBioMedicine. 98, 104882.Research output: Contribution to journal › Debate/Note/Editorial › peer-review
Open Access -
Altered Adipocyte Cell Size Distribution Prior to Weight Loss in the R6/2 Model of Huntington's Disease
Dickson, E., Fryklund, C., Soylu-Kucharz, R., Sjögren, M., Stenkula, K. G. & Björkqvist, M., 2023 Oct 3, In: Journal of Huntington's disease. 12, 3, p. 253-266 14 p.Research output: Contribution to journal › Article › peer-review
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Mutant huntingtin expression in the hypothalamus promotes ventral striatal neuropathology
Soylu Kucharz, R., Adlesic, N., Davidsson, M., Björklund, T., Björkqvist, M. & Petersén, Å., 2023 Mar 4, bioRxiv.Research output: Working paper/Preprint › Preprint (in preprint archive)
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Inflammation Biomarkers in Huntington’s Disease
Björkqvist, M., 2023, Contemporary Clinical Neuroscience. Springer Nature, p. 277-304 28 p. (Contemporary Clinical Neuroscience; vol. Part F1569).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Preserved blood-brain barrier and neurovascular coupling in female 5xFAD model of Alzheimer's disease
Zhukov, O., He, C., Soylu-Kucharz, R., Cai, C., Lauritzen, A. D., Aldana, B. I., Björkqvist, M., Lauritzen, M. & Kucharz, K., 2023, In: Frontiers in Aging Neuroscience. 15, 1089005.Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 2 Finished
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Exploring the Role of Meningeal Immune Alteration in Huntington's Disease
Björkqvist, M. (PI)
2024/05/01 → 2025/05/31
Project: Research
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BAGADILICO: Bagadilico – a joint initiative for the development of novel therapies for basal ganglia disorders
Björklund, A. (PI), Björklund, T. (PI), Björkqvist, M. (PI), Cenci Nilsson, A. (PI), Deierborg, T. (PI), Hansen, C. (PI), Hansson, O. (PI), Hansson, K. (PI), Jakobsson, J. (PI), Kirkeby, A. (PI), Laurell, T. (PI), Li, J.-Y. (PI), Liljefors, M. (PI), Londos, E. (PI), Lundberg, C. (PI), Lundin, S. (PI), Nilsson, C. (PI), Snogerup-Linse, S. (PI), Odin, P. (PI), Parmar, M. (PI), Paul-Visse, G. (PI), Rosenblad, C. (PI), Roybon, L. (PI), Swanberg, M. (PI), van Westen, D. (PI), Wictorin, K. (PI), Widner, H. (PI), van Westen, D. (PI) & Wictorin, K. (PI)
2008/07/01 → 2018/06/30
Project: Research
Activities
- 1 Supervision of PhD students
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Supervision of PhD student: Liana Fasching
Jakobsson, J. (First/primary/lead supervisor), Parmar, M. (Second supervisor), Björkqvist, M. (Commissioned member of Examining committee), Larsson, J. (Commissioned member of Examining committee) & Hedlund, E. (Commissioned member of Examining committee)
2012 → 2015 Oct 23Activity: Examination and supervision › Supervision of PhD students
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