My research focuses on the development of advanced in vitro models of the human intestine to better recapitulate physiological structure and function for biomedical research. By combining intestinal organoids with organ-on-a-chip technologies, I aim to create controllable, reproducible, and biologically relevant platforms that bridge the gap between conventional cell culture and in vivo studies.

A central aspect of my work is the use of microfluidics and microfabrication to engineer microscale environments that mimic key features of the intestinal niche, including dynamic flow, spatial organisation, and tissue-tissue interactions. I explore the integration of biomaterials and droplet microfluidics to fabricate porous scaffolds with tunable mechanical and structural properties, enabling precise control over cell adhesion, differentiation, and tissue architecture in tissue-engineered constructs.

In parallel, I develop endothelial cell models and vascular-like interfaces to study interactions between the intestinal epithelium and the vasculature. By incorporating endothelial components into microengineered systems, my work aims to capture critical aspects of nutrient transport, barrier function, and inflammatory responses that are essential for realistic intestinal models.

Overall, my research combines bioengineering, microtechnology, and cell biology to create next-generation in vitro platforms for studying intestinal physiology, disease mechanisms, and therapeutic responses, with the long-term goal of improving translational relevance and reducing reliance on animal models.