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Personal profile

Research

Functional genomics - Gene-Environment interactions on obesity and type 2 diabetes. In the post-GWAS era, to understand how the DNA variations affect metabolic disease development is crucial for precision medicine. My research interests are using CRISPR technology in adipose cell models and in combination in silicon functional annotation to revel the causal DNA variants in obesity and further understanding the biological mechanisms behind gene and environment interaction in weight loss and regain.

UKÄ subject classification

  • Cell and Molecular Biology
  • Endocrinology and Diabetes

Keywords

  • CRISPR/Cas9
  • GWAS
  • Obesity, Type 2 Diabetes, polyphenols, berries
  • alleles
  • Gene-environment interaction
  • brown adipocytes
  • white adipocytes
  • genome editing

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