Research output per year
Research output per year
Personal profile
Research
I am currently a member of the Neuroendocrine Cell Biology Group headed by Nils Wierup in Lund University Diabetes Centre. My research focuses on single-cell sequencing of the small intestinal epithelium. My previous research focused on the mechanisms of remission of Type 2 Diabetes after gastric bypass surgery. I am particularly interested in the differences in small intestinal biology between diabetics and non diabetics and would like to further understand these differences in order to develop better treatments for Type 2 Diabetes.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
UKÄ subject classification
- Cell and Molecular Biology
Free keywords
- GLP-1
- GIP
- incretin
- gastric bypass
- RYGB
- Type 2 diabetes
- remission
- Obesity, Type 2 Diabetes, polyphenols, berries
- LUDC
- Lund University Diabetes Centre
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Collaborations the last five years
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Research output
- 5 Article
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RNA sequencing unravels novel L cell constituents and mechanisms of GLP-1 secretion in human gastric bypass-operated intestine
Miskelly, M. G., Lindqvist, A., Piccinin, E., Hamilton, A., Cowan, E., Nergård, B. J., Del Giudice, R., Ngara, M., Cataldo, L. R., Kryvokhyzha, D., Volkov, P., Engelking, L., Artner, I., Lagerstedt, J. O., Eliasson, L., Ahlqvist, E., Moschetta, A., Hedenbro, J. & Wierup, N., 2024, In: Diabetologia. 67, 2, p. 356–370 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Metabolic remission precedes possible weight regain after gastric bypass surgery
Rogova, O., Herzog, K., Al-Majdoub, M., Miskelly, M., Lindqvist, A., Bennet, L., Hedenbro, J. L., Wierup, N. & Spégel, P., 2023, In: Obesity. 31, 10, p. 2530-2542Research output: Contribution to journal › Article › peer-review
Open Access -
In vivo drug discovery for increasing incretin-expressing cells identifies DYRK inhibitors that reinforce the enteroendocrine system
Chu, L., Terasaki, M., Mattsson, C. L., Teinturier, R., Charbord, J., Dirice, E., Liu, K. C., Miskelly, M. G., Zhou, Q., Wierup, N., Kulkarni, R. N. & Andersson, O., 2022 Sept 15, In: Cell Chemical Biology. 29, 9, p. 1368-1380.e5Research output: Contribution to journal › Article › peer-review
Open Access -
GK-rats respond to gastric bypass surgery with improved glycemia despite unaffected insulin secretion and beta cell mass
Miskelly, M. G., Shcherbina, L., Thorén Fischer, A. H., Abels, M., Lindqvist, A. & Wierup, N., 2021, In: Peptides. 136, 170445.Research output: Contribution to journal › Article › peer-review
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Ghrelin suppresses insulin secretion in human islets and type 2 diabetes patients have diminished islet ghrelin cell number and lower plasma ghrelin levels
Lindqvist, A., Shcherbina, L., Prasad, R. B., Miskelly, M. G., Abels, M., Martínez-Lopéz, J. A., Fred, R. G., Nergård, B. J., Hedenbro, J., Groop, L., Hjerling-Leffler, J. & Wierup, N., 2020, In: Molecular and Cellular Endocrinology. 511, 110835.Research output: Contribution to journal › Article › peer-review
Open Access