Oonagh Shannon

Oonagh Shannon

Affiliated with the university, PhD, Reader in Experimental Infection Medicine

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Immunothrombosis in sepsis

Sepsis is a life-threatening condition that can occur following infection. Multicomponent host-pathogen interactions within the bloodstream contribute to the transition from local infection to the systemic dysregulation of the immune response in sepsis. Molecular and cellular events in the blood generate an immunothrombosis in sepsis. Our research is focused on characterizing these events using a unique combination of in-vitro functional profiling of pathogen activated blood cells with experimental modelling of sepsis in-vivo. We aim to discover and implement biomarker panels to guide diagnosis of sepsis and identify therapeutic targets to predict and prevent organ damage in sepsis.

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

UKÄ subject classification

  • Medical and Health Sciences
  • Microbiology in the medical area
  • Immunology in the medical area

Free keywords

  • sepsis, Platelets, Streptococcus


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Collaborations and top research areas from the last five years

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