Research output per year
Research output per year
- 33 results
Search results
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2024
Inflammatory bowel disease induces pathological α-synuclein aggregation in the human gut and brain
Espinosa-Oliva, A. M., Ruiz, R., Soto, M. S., Boza-Serrano, A., Rodriguez-Perez, A. I., Roca-Ceballos, M. A., García-Revilla, J., Santiago, M., Serres, S., Economopoulus, V., Carvajal, A. E., Vázquez-Carretero, M. D., García-Miranda, P., Klementieva, O., Oliva-Martín, M. J., Deierborg, T., Rivas, E., Sibson, N. R., Labandeira-García, J. L. & Machado, A. & 4 others, , 2024 Feb, In: Neuropathology and Applied Neurobiology. 50, 1, e12962.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Label-FreeHigh-ResolutionPhotothermalOpticalInfraredSpectroscopyfor Spatiotemporal Chemica lAnalysis in Fresh, Hydrated Living Tissues and Embryos
Gvazava, N., Konings, S., Cepeda-Prado, E., Skoryk, V., Harrison Umeano, C., Dong, J., Augusto Silva, I., Rylander Ottosson , D., Leigh, N., Wagner, D. & Klementieva, O., 2023 Nov 2, In: Journal of the American Chemical Society.Research output: Contribution to journal › Article › peer-review
Open Access -
Maternal separation differentially modulates early pathology by sex in 5xFAD Alzheimer’s disease-transgenic mice
Garcia, M. G., Paulus, A., Vázquez-Reyes, S., Klementieva, O., Gouras, G. K., Bachiller, S. & Deierborg, T., 2023 Oct, In: Brain, Behavior, & Immunity - Health. 32, 10 p., 100663.Research output: Contribution to journal › Article › peer-review
Open Access -
Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer's disease pathogenesis
Pomeshchik, Y., Velasquez, E., Gil, J., Klementieva, O., Gidlöf, R., Sydoff, M., Bagnoli, S., Nacmias, B., Sorbi, S., Westergren-Thorsson, G., Gouras, G. K., Rezeli, M. & Roybon, L., 2023 Sept 15, In: Acta Neuropathologica Communications. 11, 150.Research output: Contribution to journal › Article › peer-review
Open Access -
Apolipoprotein E intersects with amyloid-β within neurons
Konings, S. C., Nyberg, E., Martinsson, I., Torres-Garcia, L., Klementieva, O., Guimas Almeida, C. & Gouras, G. K., 2023 Aug, In: Life Science Alliance. 6, 8, e202201887.Research output: Contribution to journal › Article › peer-review
Open Access -
Galectin-3 shapes toxic alpha-synuclein strains in Parkinson’s disease
García-Revilla, J., Boza-Serrano, A., Jin, Y., Vadukul, D. M., Soldán-Hidalgo, J., Camprubí-Ferrer, L., García-Cruzado, M., Martinsson, I., Klementieva, O., Ruiz, R., Aprile, F. A., Deierborg, T. & Venero, J. L., 2023 Jul, In: Acta Neuropathologica. 146, 1, p. 51-75 25 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Formalin-free fixation and xylene-free tissue processing preserves cell-hydrogel interactions for histological evaluation of 3D calcium alginate tissue engineered constructs
Augusto Silva, I., Gvazava, N., Wendi, I. P., Guinea Ordonez, R. J., Garcia Gimenez, F., Stegmayr, J., Klementieva, O. & Wagner, D., 2023 Apr 17, In: Frontiers in Biomaterials Science. 2-2023, 1155919Research output: Contribution to journal › Article › peer-review
Open Access -
Bioactive Suture with Added Innate Defense Functionality for the Reduction of Bacterial Infection and Inflammation
Puthia, M., Petrlova, J., Petruk, G., Butrym, M., Samsudin, F., Andersson, M. Å., Strömdahl, A.-C., Wasserstrom, S., Hartman, E., Kjellström, S., Caselli, L., Klementieva, O., Bond, P. J., Malmsten, M., Raina, D. & Schmidtchen, A., 2023, In: Advanced healthcare materials. 12, 31Research output: Contribution to journal › Article › peer-review
Open Access -
Fluorescently Guided Optical Photothermal Infrared Microspectroscopy for Protein-Specific Bioimaging at Subcellular Level
Prater, C., Bai, Y., Konings, S. C., Martinsson, I., Swaminathan, V. S., Nordenfelt, P., Gouras, G., Borondics, F. & Klementieva, O., 2023, In: Journal of Medicinal Chemistry. 66, 4, p. 2542-2549Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Early-life stress elicits peripheral and brain immune activation differently in wild type and 5xFAD mice in a sex-specific manner
Bachiller, S., Hidalgo, I., Garcia, M. G., Boza-Serrano, A., Paulus, A., Denis, Q., Haikal, C., Manouchehrian, O., Klementieva, O., Li, J. Y., Pronk, C. J., Gouras, G. K. & Deierborg, T., 2022 Jun 15, In: Journal of Neuroinflammation. 19, 151.Research output: Contribution to journal › Article › peer-review
Open Access -
Recommendations for addressing the translational gap between experimental and clinical research on amyloid diseases
Solomon, M., Fodera, V., Langkilde, A. E., Elliott, P., Tagliavini, F., Forsyth, T., Klementieva, O. & Bellotti, V., 2022 May 13, In: Journal of Translational Medicine. 20, 213, p. 1-7 7 p., 213.Research output: Contribution to journal › Article › peer-review
Open Access -
Correlative imaging to resolve molecular structures in individual cells: Substrate validation study for super-resolution infrared microspectroscopy
Paulus, A., Yogarasa, S., Kansiz, M., Martinsson, I., Gouras, G. K., Deierborg, T., Engdahl, A., Borondics, F. & Klementieva, O., 2022, In: Nanomedicine: Nanotechnology, Biology and Medicine. 43, p. 102563 102563.Research output: Contribution to journal › Article › peer-review
Open Access -
Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties
Azevedo, C., Teku, G., Pomeshchik, Y., Reyes, J. F., Chumarina, M., Russ, K., Savchenko, E., Hammarberg, A., Lamas, N. J., Collin, A., Gouras, G. K., Klementieva, O., Hallbeck, M., Taipa, R., Vihinen, M. & Roybon, L., 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 12, e2111405119.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Correlative optical photothermal infrared and X-ray fluorescence for chemical imaging of trace elements and relevant molecular structures directly in neurons
Gustavsson, N., Paulus, A., Martinsson, I., Engdahl, A., Medjoubi, K., Klementiev, K., Somogyi, A., Deierborg, T., Borondics, F., Keppler Gouras, G. & Klementieva, O., 2021 Jul 22, In: Light, science & applications. 10, p. 1-10 10 p., 151.Research output: Contribution to journal › Article › peer-review
Open Access -
Amyloid Structural Changes Studied by Infrared Microspectroscopy in Bigenic Cellular Models of Alzheimer’s Disease
Paulus, A., Engdahl, A., Yang, Y., Boza Serrano, A., Bachiller, S., Torres-Garcia, L., Svanbergsson, A., Garcia, M., Keppler Gouras, G., Li, J.-Y., Deierborg, T. & Klementieva, O., 2021 Mar 26, In: International Journal of Molecular Sciences. 22, 7, 3430.Research output: Contribution to journal › Article › peer-review
Open Access -
In situ identification and G4-PPI-His-Mal-dendrimer-induced reduction of early-stage amyloid aggregates in Alzheimer’s disease transgenic mice using synchrotron-based infrared imaging
Benseny-Cases, N., Álvarez-Marimon, E., Aso, E., Carmona, M., Klementieva, O., Appelhans, D., Ferrer, I. & Cladera, J., 2021, In: Scientific Reports. 11, 1, 18368.Research output: Contribution to journal › Article › peer-review
Open Access -
Nano-Infrared Imaging of Primary Neurons
O. Freitas, R., Cernescu , A., Engdahl, A., Paulus, A., E. Levandoski , J., Martinsson, I., Hebisch, E., Sandt, C., Keppler Gouras, G., Prinz, C., Deierborg, T., Borondics, F. & Klementieva, O., 2021, In: Cells. 10, 10, p. 1-15 2559.Research output: Contribution to journal › Article › peer-review
Open Access -
The intracellular milieu of Parkinson’s disease patient brain cells modulates alpha-synuclein protein aggregation
Gustavsson, N., Savchenko, E., Klementieva, O. & Roybon, L., 2021, In: Acta Neuropathologica Communications. 9, 1, 153.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Super‐Resolution Infrared Imaging of Polymorphic Amyloid Aggregates Directly in Neurons
Klementieva, O., Sandt, C., Martinsson, I., Kansiz, M., Keppler Gouras, G. & Borondics, F., 2020 Feb 7, In: Advanced Science. 9 p., 1903004.Research output: Contribution to journal › Article › peer-review
Open Access -
Human iPSC-Derived Hippocampal Spheroids: An Innovative Tool for Stratifying Alzheimer Disease Patient-Specific Cellular Phenotypes and Developing Therapies
Pomeshchik, Y., Klementieva, O., Gil, J., Martinsson, I., Hansen, M. G., de Vries, T., Sancho-Balsells, A., Russ, K., Savchenko, E., Collin, A., Vaz, A. R., Bagnoli, S., Nacmias, B., Rampon, C., Sorbi, S., Brites, D., Marko-Varga, G., Kokaia, Z., Rezeli, M. & Gouras, G. K. & 1 others, , 2020, In: Stem Cell Reports. 15, 1, p. 256-273 18 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Generation of an induced pluripotent stem cell line (CSC-46) from a patient with Parkinson's disease carrying a novel p.R301C mutation in the GBA gene
Gustavsson, N., Marote, A., Pomeshchik, Y., Russ, K., Azevedo, C., Chumarina, M., Goldwurm, S., Collin, A., Pinto, L., Salgado, A. J., Klementieva, O., Roybon, L. & Savchenko, E., 2019, In: Stem Cell Research. 34, 101373.Research output: Contribution to journal › Article › peer-review
Open Access -
Poly(propylene imine) dendrimers with histidine-maltose shell as novel type of nanoparticles for synapse and memory protection.
Aso, E., Martinsson, I., Appelhans, D., Effenberg, C., Benseny-Cases, N., Gouras, G., Ferrer, I. & Klementieva, O., 2019, In: Nanomedicine: Nanotechnology, Biology, and Medicine. p. 198-209Research output: Contribution to journal › Article › peer-review
Open Access -
2018
Prion-like seeding and nucleation of intracellular amyloid-β
Olsson, T. T., Klementieva, O. & Gouras, G. K., 2018 May 1, In: Neurobiology of Disease. 113, p. 1-10 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
S100A9-Driven Amyloid-Neuroinflammatory Cascade in Traumatic Brain Injury as a Precursor State for Alzheimer’s Disease
Wang, C., Iashchishyn, I. A., Pansieri, J., Nyström, S., Klementieva, O., Kara, J., Horvath, I., Moskalenko, R., Rofougaran, R., Gouras, G., Kovacs, G. G., Shankar, S. K. & Morozova-Roche, L. A., 2018, In: Scientific Reports. 8, 1, 12836.Research output: Contribution to journal › Article › peer-review
Open Access -
2017
3D membrane segmentation and quantification of intact thick cells using cryo soft X-ray transmission microscopy: A pilot study
Cárdenes, R., Zhang, C., Klementieva, O., Werner, S., Guttmann, P., Pratsch, C., Cladera, J. & Bijnens, B. H., 2017 Apr 1, In: PLoS ONE. 12, 4, e0174324.Research output: Contribution to journal › Article › peer-review
Open Access -
Pre-plaque conformational changes in Alzheimer's disease-linked Aβ and APP
Klementieva, O., Willén, K., Martinsson, I., Israelsson, B., Engdahl, A., Cladera, J., Uvdal, P. & Gouras, G. K., 2017 Mar 13, In: Nature Communications. 8, 14726.Research output: Contribution to journal › Article › peer-review
Open Access -
2014
Microspectroscopy (μFTIR) reveals co-localization of lipid oxidation and amyloid plaques in human Alzheimer disease brains
Benseny-Cases, N., Klementieva, O., Cotte, M., Ferrer, I. & Cladera, J., 2014 Dec 16, In: Analytical Chemistry. 86, 24, p. 12047-54Research output: Contribution to journal › Article › peer-review
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Detection of pre-plaque amyloid aggregation using FTIR
Klementieva, O., Engdahl, A., Faideau, M., Willén, K., Uvdal, P. & Keppler Gouras, G., 2014 Jul 1, In: Alzheimer's and Dementia. 10, 4Research output: Contribution to journal › Article › peer-review
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2013
Effect of poly(propylene imine) glycodendrimers on β-amyloid aggregation in vitro and in APP/PS1 transgenic mice, as a model of brain amyloid deposition and Alzheimer's disease
Klementieva, O., Aso, E., Filippini, D., Benseny-Cases, N., Carmona, M., Juvés, S., Appelhans, D., Cladera, J. & Ferrer, I., 2013 Oct 14, In: Biomacromolecules. 14, 10, p. 3570-80Research output: Contribution to journal › Article › peer-review
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2012
Granular non-fibrillar aggregates and toxicity in Alzheimer's disease
Benseny-Cases, N., Klementieva, O., Malý, J. & Cladera, J., 2012 Oct, In: Current Alzheimer Research. 9, 8, p. 962-71 10 p.Research output: Contribution to journal › Article › peer-review
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Phosphorus dendrimers affect Alzheimer's (Aβ 1-28) peptide and MAP-Tau protein aggregation
Wasiak, T., Ionov, M., Nieznanski, K., Nieznanska, H., Klementieva, O., Granell, M., Cladera, J., Majoral, J. P., Caminade, A. M. & Klajnert, B., 2012 Mar 5, In: Molecular Pharmaceutics. 9, 3, p. 458-469 12 p.Research output: Contribution to journal › Article › peer-review
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Dendrimers antiamyloidogenic potential in neurodegenerative diseases
Benseny-Cases, N., Klementieva, O. & Cladera, J., 2012 Feb 1, In: New Journal of Chemistry. 36, 2, p. 211-216 6 p.Research output: Contribution to journal › Article › peer-review
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2011
Dense shell glycodendrimers as potential nontoxic anti-amyloidogenic agents in Alzheimer's disease. Amyloid-dendrimer aggregates morphology and cell toxicity
Klementieva, O., Benseny-Cases, N., Gella, A., Appelhans, D., Voit, B. & Cladera, J., 2011 Nov 14, In: Biomacromolecules. 12, 11, p. 3903-9Research output: Contribution to journal › Article › peer-review