Pablo Peña - Research output - Lund University

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11 Article
1 Doctoral Thesis (compilation)

12 results

2024
Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4-r cases
Thorsson, H., Henningsson, R., Puente-Moncada, N., Peña-Martínez, P., Sjöström, L., Ågerstam, H., Sandén, C., Rissler, M., Castor, A., Marquart, H., Modvig, S., Paulsson, K., Pronk, C. J., Schmiegelow, K., Hyrenius-Wittsten, A., Orsmark-Pietras, C., Lilljebjörn, H. & Fioretos, T., 2024 Sept 26, In: Blood. 144, 13, p. 1399-1411
Research output: Contribution to journal › Article › peer-review
2023
Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity
Rodriguez-Zabala, M., Ramakrishnan, R., Reinbach, K., Ghosh, S., Oburoglu, L., Falqués-Costa, A., Bellamkonda, K., Ehinger, M., Peña-Martínez, P., Puente-Moncada, N., Lilljebjörn, H., Cammenga, J., Pronk, C. J., Lazarevic, V., Fioretos, T., Hagström-Andersson, A. K., Woods, N. B. & Järås, M., 2023 Sept 26, In: Blood Advances. 7, 18, p. 5382-5395
Research output: Contribution to journal › Article › peer-review

Open Access
The complement receptor C3AR constitutes a novel therapeutic target in NPM1-mutated AML
von Palffy, S., Thorsson, H., Peña-Martínez, P., Puente-Moncada, N., Sandén, C., Blom, A. M., Henningsson, R., Juliusson, G., King, B., Landberg, N., Lazarevic, V. L., Orsmark-Pietras, C., Rissler, M., Rissler, V., Ågerstam, H., Järås, M., Lilljebjörn, H. & Fioretos, T., 2023, In: Blood Advances. 7, 7, p. 1204-1218
Research output: Contribution to journal › Article › peer-review
2022
Interleukin 4 promotes phagocytosis of murine leukemia cells counteracted by CD47 upregulation
Peña-Martínez, P., Ramakrishnan, R., Högberg, C., Jansson, C., Nord, D. G. & Järås, M., 2022 Apr, In: Haematologica. 107, 4, p. 816-824 9 p.
Research output: Contribution to journal › Article › peer-review
2021
Sister chromatid cohesion defects are associated with chromosomal copy number heterogeneity in high hyperdiploid childhood acute lymphoblastic leukemia
Moura-Castro, L. H., Peña-Martínez, P., Castor, A., Galeev, R., Larsson, J., Järås, M., Yang, M. & Paulsson, K., 2021 Jun 1, In: Genes Chromosomes and Cancer. 60, 6, p. 410-417 8 p.
Research output: Contribution to journal › Article › peer-review

Open Access
2020
CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia
Ramakrishnan, R., Peña-Martínez, P., Agarwal, P., Rodriguez-Zabala, M., Chapellier, M., Högberg, C., Eriksson, M., Yudovich, D., Shah, M., Ehinger, M., Nilsson, B., Larsson, J., Hagström-Andersson, A., Ebert, B. L., Bhatia, R. & Järås, M., 2020 May 26, In: Cell Reports. 31, 8, 107684.
Research output: Contribution to journal › Article › peer-review

Open Access
Clonal competition within complex evolutionary hierarchies shapes AML over time
Sandén, C., Lilljebjörn, H., Orsmark Pietras, C., Henningsson, R., Saba, K. H., Landberg, N., Thorsson, H., von Palffy, S., Peña-Martinez, P., Högberg, C., Rissler, M., Gisselsson, D., Lazarevic, V., Juliusson, G., Ågerstam, H. & Fioretos, T., 2020, In: Nature Communications. 11, 1, 579.
Research output: Contribution to journal › Article › peer-review

Open Access
2019
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells
Chapellier, M., Peña-Martínez, P., Ramakrishnan, R., Eriksson, M., Safaee-Talkhoncheh, M., Orsmark-Pietras, C., Lilljebjörn, H., Högberg, C., Hagström-Andersson, A., Fioretos, T., Larsson, J. & Järås, M., 2019, In: Haematologica. 104, 10, p. 2006-2016
Research output: Contribution to journal › Article › peer-review

Open Access
2018
Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6 dependent manner
Peña, P., Eriksson, M., Ramakrishnan, R., Chapellier, M., Högberg, C., Orsmark-Pietras, C., Richter, J., Andersson, A., Fioretos, T. & Järås, M., 2018, In: Leukemia. 32, 3, p. 588-596
Research output: Contribution to journal › Article › peer-review

Open Access
Studies of Ligands and Receptors Regulating Acute Myeloid Leukemia
Peña, P., 2018, Lund: Lund University: Faculty of Medicine. 72 p.
Research output: Thesis › Doctoral Thesis (compilation)

Open Access
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2017
Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells
Eriksson, M., Peña-Martínez, P., Ramakrishnan, R., Chapellier, M., Högberg, C., Glowacki, G., Orsmark-Pietras, C., Velasco-Hernández, T., Lazarević, V. L., Juliusson, G., Cammenga, J., Mulloy, J. C., Richter, J., Fioretos, T., Ebert, B. L. & Järås, M., 2017 Oct 24, In: Blood Advances. 1, 23, p. 2046-2057 12 p.
Research output: Contribution to journal › Article › peer-review
2014
Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia
Järås, M., Miller, P. G., Chu, L. P., Puram, R. V., Fink, E. C., Schneider, R. K., Al-Shahrour, F., Peña, P., Breyfogle, L. J., Hartwell, K. A., McConkey, M. E., Cowley, G. S., Root, D. E., Kharas, M. G., Mullally, A. & Ebert, B. L., 2014, In: Journal of Experimental Medicine. 211, 4, p. 605-612
Research output: Contribution to journal › Article › peer-review