Research output per year
Research output per year
- 11 results
Search results
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2024
Single-cell genomics details the maturation block in BCP-ALL and identifies therapeutic vulnerabilities in DUX4-r cases
Thorsson, H., Henningsson, R., Puente-Moncada, N., Peña-Martínez, P., Sjöström, L., Ågerstam, H., Sandén, C., Rissler, M., Castor, A., Marquart, H., Modvig, S., Paulsson, K., Pronk, C. J., Schmiegelow, K., Hyrenius-Wittsten, A., Orsmark-Pietras, C., Lilljebjörn, H. & Fioretos, T., 2024 Sept 26, In: Blood. 144, 13, p. 1399-1411Research output: Contribution to journal › Article › peer-review
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2023
Combined GLUT1 and OXPHOS inhibition eliminates acute myeloid leukemia cells by restraining their metabolic plasticity
Rodriguez-Zabala, M., Ramakrishnan, R., Reinbach, K., Ghosh, S., Oburoglu, L., Falqués-Costa, A., Bellamkonda, K., Ehinger, M., Peña-Martínez, P., Puente-Moncada, N., Lilljebjörn, H., Cammenga, J., Pronk, C. J., Lazarevic, V., Fioretos, T., Hagström-Andersson, A. K., Woods, N. B. & Järås, M., 2023 Sept 26, In: Blood Advances. 7, 18, p. 5382-5395Research output: Contribution to journal › Article › peer-review
Open Access -
The complement receptor C3AR constitutes a novel therapeutic target in NPM1-mutated AML
von Palffy, S., Thorsson, H., Peña-Martínez, P., Puente-Moncada, N., Sandén, C., Blom, A. M., Henningsson, R., Juliusson, G., King, B., Landberg, N., Lazarevic, V. L., Orsmark-Pietras, C., Rissler, M., Rissler, V., Ågerstam, H., Järås, M., Lilljebjörn, H. & Fioretos, T., 2023, In: Blood Advances. 7, 7, p. 1204-1218Research output: Contribution to journal › Article › peer-review
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2022
Interleukin 4 promotes phagocytosis of murine leukemia cells counteracted by CD47 upregulation
Peña-Martínez, P., Ramakrishnan, R., Högberg, C., Jansson, C., Nord, D. G. & Järås, M., 2022 Apr, In: Haematologica. 107, 4, p. 816-824 9 p.Research output: Contribution to journal › Article › peer-review
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2021
Sister chromatid cohesion defects are associated with chromosomal copy number heterogeneity in high hyperdiploid childhood acute lymphoblastic leukemia
Moura-Castro, L. H., Peña-Martínez, P., Castor, A., Galeev, R., Larsson, J., Järås, M., Yang, M. & Paulsson, K., 2021 Jun 1, In: Genes Chromosomes and Cancer. 60, 6, p. 410-417 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2020
CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia
Ramakrishnan, R., Peña-Martínez, P., Agarwal, P., Rodriguez-Zabala, M., Chapellier, M., Högberg, C., Eriksson, M., Yudovich, D., Shah, M., Ehinger, M., Nilsson, B., Larsson, J., Hagström-Andersson, A., Ebert, B. L., Bhatia, R. & Järås, M., 2020 May 26, In: Cell Reports. 31, 8, 107684.Research output: Contribution to journal › Article › peer-review
Open Access -
Clonal competition within complex evolutionary hierarchies shapes AML over time
Sandén, C., Lilljebjörn, H., Orsmark Pietras, C., Henningsson, R., Saba, K. H., Landberg, N., Thorsson, H., von Palffy, S., Peña-Martinez, P., Högberg, C., Rissler, M., Gisselsson, D., Lazarevic, V., Juliusson, G., Ågerstam, H. & Fioretos, T., 2020, In: Nature Communications. 11, 1, 579.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Arrayed molecular barcoding identifies TNFSF13 as a positive regulator of acute myeloid leukemia-initiating cells
Chapellier, M., Peña-Martínez, P., Ramakrishnan, R., Eriksson, M., Safaee-Talkhoncheh, M., Orsmark-Pietras, C., Lilljebjörn, H., Högberg, C., Hagström-Andersson, A., Fioretos, T., Larsson, J. & Järås, M., 2019, In: Haematologica. 104, 10, p. 2006-2016Research output: Contribution to journal › Article › peer-review
Open Access -
2018
Interleukin 4 induces apoptosis of acute myeloid leukemia cells in a Stat6 dependent manner
Peña, P., Eriksson, M., Ramakrishnan, R., Chapellier, M., Högberg, C., Orsmark-Pietras, C., Richter, J., Andersson, A., Fioretos, T. & Järås, M., 2018, In: Leukemia. 32, 3, p. 588-596Research output: Contribution to journal › Article › peer-review
Open Access -
2017
Agonistic targeting of TLR1/TLR2 induces p38 MAPK-dependent apoptosis and NFκB-dependent differentiation of AML cells
Eriksson, M., Peña-Martínez, P., Ramakrishnan, R., Chapellier, M., Högberg, C., Glowacki, G., Orsmark-Pietras, C., Velasco-Hernández, T., Lazarević, V. L., Juliusson, G., Cammenga, J., Mulloy, J. C., Richter, J., Fioretos, T., Ebert, B. L. & Järås, M., 2017 Oct 24, In: Blood Advances. 1, 23, p. 2046-2057 12 p.Research output: Contribution to journal › Article › peer-review
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2014
Csnk1a1 inhibition has p53-dependent therapeutic efficacy in acute myeloid leukemia
Järås, M., Miller, P. G., Chu, L. P., Puram, R. V., Fink, E. C., Schneider, R. K., Al-Shahrour, F., Peña, P., Breyfogle, L. J., Hartwell, K. A., McConkey, M. E., Cowley, G. S., Root, D. E., Kharas, M. G., Mullally, A. & Ebert, B. L., 2014, In: Journal of Experimental Medicine. 211, 4, p. 605-612Research output: Contribution to journal › Article › peer-review