Per Kjellbom

2022

Characterization of the Aquaporin-9 Inhibitor RG100204 In Vitro and in db/db Mice

Florio, M., Engfors, A., Gena, P., Larsson, J., Massaro, A., Timpka, S., Kvist Reimer, M., Kjellbom, P., Beitz, E., Johanson, U., Rützler, M. & Calamita, G., 2022 Oct 4, In: Cells. 11, 19, 11 p., 3118.

Research output: Contribution to journal › Article › peer-review

Open Access

2020

Electrophile-Induced Conformational Switch of the Human TRPA1 Ion Channel Detected by Mass Spectrometry

Moparthi, L., Kjellström, S., Kjellbom, P., Filipovic, M. R., Zygmunt, P. M. & Johanson, U., 2020 Sept 11, In: International Journal of Molecular Sciences. 21, 18, 6667.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors

Sonntag, Y., Gena, P., Maggio, A., Singh, T., Artner, I., Oklinski, M. K., Johanson, U., Kjellbom, P., Nieland, J. D., Nielsen, S., Calamita, G. & Rützler, M., 2019, In: Journal of Biological Chemistry. 294, 18, p. 7377-7387 20 p.

Research output: Contribution to journal › Article › peer-review

2018

A structural preview of aquaporin 8 via homology modeling of seven vertebrate isoforms

Kirscht, A., Sonntag, Y., Kjellbom, P. & Johanson, U., 2018 Feb 17, In: BMC Structural Biology. 18, 1, 81.

Research output: Contribution to journal › Article › peer-review

Open Access

2017

Single amino acid substitutions in the selectivity filter render NbXIP1;1α aquaporin water permeable

Ampah-Korsah, H., Sonntag, Y., Engfors, A., Kirscht, A., Kjellbom, P. & Johanson, U., 2017 Mar 9, In: BMC Plant Biology. 17, 1, p. 61

Research output: Contribution to journal › Article › peer-review

Open Access

2016

The N-terminal Ankyrin Repeat domain is not required for electrophile and heat activation of the purified mosquito TRPA1 receptor

Survery, S., Moparthi, L., Kjellbom, P., Högestätt, E. D., Zygmunt, P. M. & Johanson, U., 2016 Dec 23, In: Journal of Biological Chemistry. 291, 52, p. 26899-26912 14 p.

Research output: Contribution to journal › Article › peer-review

Increased Permeability of the Aquaporin SoPIP2;1 by Mercury and Mutations in Loop A

Kirscht, A., Survery, S., Kjellbom, P. & Johanson, U., 2016 Aug 30, In: Frontiers in Plant Science. 7, p. 1-11 11 p., 1249.

Research output: Contribution to journal › Article › peer-review

Open Access

The aquaporin splice variant NbXIP1;1α is permeable to boric acid and is Phosphorylated in the N-terminal domain

Ampah-Korsah, H., Anderberg, H. I., Engfors, A., Kirscht, A., Nordén, K., Kjellström, S., Kjellbom, P. & Johanson, U., 2016 Jun 16, In: Frontiers in Plant Science. 7, JUNE2016, 862.

Research output: Contribution to journal › Article › peer-review

Open Access

Crystal Structure of an Ammonia-Permeable Aquaporin

Kirscht, A., Kaptan, S. S., Bienert, G. P., Chaumont, F., Nissen, P., de Groot, B. L., Kjellbom, P., Gourdon, P. & Johanson, U., 2016 Mar 30, In: PLoS Biology. 14, 3, e1002411.

Research output: Contribution to journal › Article › peer-review

Open Access

Human TRPA1 is a heat sensor displaying intrinsic U-shaped thermosensitivity

Moparthi, L., Kichko, T. I., Eberhardt, M., Högestätt, E. D., Kjellbom, P., Johanson, U., Reeh, P. W., Leffler, A., Filipovic, M. R. & Zygmunt, P. M., 2016, In: Scientific Reports. 6, 28763.

Research output: Contribution to journal › Article › peer-review

Open Access

2015

Deletion of glycerol channel aquaporin-9 (Aqp9) impairs long-term blood glucose control in C57BL/6 leptin receptor-deficient (db/db) obese mice.

Spégel, P., Chawade, A., Nielsen, S., Kjellbom, P. & Rützler, M., 2015, In: Physiological Reports. 3, 9, e12538.

Research output: Contribution to journal › Article › peer-review

Open Access

2014

In Vitro Selection of RNA Aptamers Directed Against Protein E: A Haemophilus influenzae Adhesin. a Haemophilus influenzae adhesin

Barfod, A., Singh, B., Johanson, U., Riesbeck, K. & Kjellbom, P., 2014 Aug, In: Molecular Biotechnology. 56, 8, p. 714-725 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Human TRPA1 is intrinsically cold- and chemosensitive with and without its N-terminal ankyrin repeat domain.

Moparthi, L., Survery, S., Kreir, M., Simonsen, C., Kjellbom, P., Högestätt, E., Johanson, U. & Zygmunt, P., 2014, In: Proceedings of the National Academy of Sciences. 111, 47, p. 16901-16906

Research output: Contribution to journal › Article › peer-review

Open Access

2013

The identification of novel, high affinity AQP9 inhibitors in an intracellular binding site

Wacker, S. J., Aponte-Santamaria, C., Kjellbom, P., Nielsen, S., de Groot, B. L. & Rûtzler, M., 2013, In: Molecular Membrane Biology. 30, 3, p. 246-260

Research output: Contribution to journal › Article › peer-review

2012

Annotation of Selaginella moellendorffii Major Intrinsic Proteins and the Evolution of the Protein Family in Terrestrial Plants.

Anderberg, H., Kjellbom, P. & Johanson, U., 2012, In: Frontiers in Plant Science. 3, 33.

Research output: Contribution to journal › Article › peer-review

Open Access

Reconstitution of water channel function and 2D-crystallization of human aquaporin 8.

Agemark, M., Kowal, J., Kukulski, W., Nordén, K., Gustavsson, N., Johanson, U., Engel, A. & Kjellbom, P., 2012, In: Biochimica et Biophysica Acta. 1818, 3, p. 839-850

Research output: Contribution to journal › Article › peer-review

Open Access

Solute transport on the sub 100 ms scale across the lipid bilayer membrane of individual proteoliposomes

Ohlsson, G., Tabaei, S. R., Beech, J., Kvassman, J., Johanson, U., Kjellbom, P., Tegenfeldt, J. & Höök, F., 2012, In: Lab on a Chip. 12, 22, p. 4635-4643 9 p.

Research output: Contribution to journal › Article › peer-review

2011

Aquaporin-9 Protein Is the Primary Route of Hepatocyte Glycerol Uptake for Glycerol Gluconeogenesis in Mice

Jelen, S., Wacker, S., Aponte-Santamaria, C., Skott, M., Rojek, A., Johanson, U., Kjellbom, P., Nielsen, S., de Groot, B. L. & Ruetzler, M., 2011, In: Journal of Biological Chemistry. 286, 52, p. 44319-44325

Research output: Contribution to journal › Article › peer-review

Open Access

Increasing gene dosage greatly enhances recombinant expression of aquaporins in Pichia pastoris

Nordén, K., Agemark, M., Danielson, J., Alexandersson, E., Kjellbom, P. & Johanson, U., 2011, In: BMC Biotechnology. 11

Research output: Contribution to journal › Article › peer-review

Open Access

Structure and Stability of the Spinach Aquaporin SoPIP2;1 in Detergent Micelles and Lipid Membranes

Plasencia, I., Survery, S., Ibragimova, S., Hansen, J. S., Kjellbom, P., Helix-Nielsen, C., Johanson, U. & Mouritsen, O. G., 2011, In: PLoS ONE. 6, 2

Research output: Contribution to journal › Article › peer-review

Open Access

2010

Transcriptional regulation of aquaporins in accessions of Arabidopsis in response to drought stress.

Alexandersson, E., Danielson, J., Råde, J., Moparthi, V., Fontes, M., Kjellbom, P. & Johanson, U., 2010, In: Plant Journal. 61, p. 650-660

Research output: Contribution to journal › Article › peer-review

2008

Affinity tags can reduce merohedral twinning of membrane protein crystals

Backmark, A., Nyblom, M., Tornroth-Horsefield, S., Kosinska-Eriksson, U., Nordén, K., Agemark, M., Kjellbom, P., Johanson, U., Hedfalk, K., Lindkvist- ersson, K., Neutze, R. & Horsefield, R., 2008, In: Acta Crystallographica. Section D: Biological Crystallography. 64, p. 1183-1186

Research output: Contribution to journal › Article › peer-review

High-resolution x-ray structure of human aquaporin 5

Horsefield, R., Nordén, K., Agemark, M., Backmark, A., Tornroth-Horsefield, S., van Scheltinga, A. C. T., Kvassman, J., Kjellbom, P., Johanson, U. & Neutze, R., 2008, In: Proceedings of the National Academy of Sciences. 105, 36, p. 13327-13332

Research output: Contribution to journal › Article › peer-review

Open Access

Purification and proteomic analysis of plant plasma membranes.

Alexandersson, E., Gustavsson, N., Bernfur, K., Karlsson, A., Kjellbom, P. & Larsson, C., 2008, In: Methods in Molecular Biology. 432, p. 161-173

Research output: Contribution to journal › Article › peer-review

The effects of the loss of TIP1;1 and TIP1;2 aquaporins in Arabidopsis thaliana

Schussler, M. D., Alexandersson, E., Bienert, G. P., Kichey, T., Laursen, K. H., Johanson, U., Kjellbom, P., Schjoerring, J. K. & Jahn, T. P., 2008, In: Plant Journal. 56, 5, p. 756-767

Research output: Contribution to journal › Article › peer-review

2007

HvPIP1;6, a barley (Hordeum vulgare L.) plasma membrane water channel particularly expressed in growing compared with non-growing leaf tissues

Wei, W., Alexandersson, E., Golldack, D., Miller, A. J., Kjellbom, P. & Fricke, W., 2007, In: Plant and Cell Physiology. 48, 8, p. 1132-1147

Research output: Contribution to journal › Article › peer-review

2006

Purification and characterization of two protein kinases acting on the aquaporin SoPIP2; 1

Sjövall Larsen, S., Alexandersson, E., Johansson, I., Karlsson, M., Johanson, U. & Kjellbom, P., 2006, In: Biochimica et Biophysica Acta - Biomembranes. 1758, 8, p. 1157-1164

Research output: Contribution to journal › Article › peer-review

Open Access

Structural mechanism of plant aquaporin gating

Tornroth-Horsefield, S., Wang, Y., Hedfalk, K., Johanson, U., Karlsson, M., Tajkhorshid, E., Neutze, R. & Kjellbom, P., 2006, In: Nature. 439, 7077, p. 688-694

Research output: Contribution to journal › Article › peer-review

The short-term growth response to salt of the developing barley leaf

Fricke, W., Akhiyarova, G., Wei, W., Alexandersson, E., Miller, A., Kjellbom, P., Richardson, A., Wojciechowski, T., Schreiber, L., Veselov, D., Kudoyarova, G. & Volkov, V., 2006, In: Journal of Experimental Botany. 57, 5, p. 1079-1095

Research output: Contribution to journal › Article › peer-review

Open Access

2005

Specific plasma membrane aquaporins of the PIP1 subfamily are expressed in sieve elements and guard cells

Fraysse, L., Wells, B., McCann, M. C. & Kjellbom, P., 2005, In: Biology of the Cell. 97, 7, p. 519-534

Research output: Contribution to journal › Article › peer-review

The 5 angstrom structure of heterologously expressed plant aquaporin SoPIP2;1

Kukulski, W., Schenk, A. D., Johanson, U., Braun, T., de Groot, B. L., Fotiadis, D., Kjellbom, P. & Engel, A., 2005, In: Journal of Molecular Biology. 350, 4, p. 611-616

Research output: Contribution to journal › Article › peer-review

Whole gene family expression and drought stress regulation of aquaporins

Alexandersson, E., Fraysse, L., Sjövall Larsen, S., Gustavsson, S., Agemark, M., Karlsson, M., Johanson, U. & Kjellbom, P., 2005, In: Plant Molecular Biology. 59, 3, p. 469-484

Research output: Contribution to journal › Article › peer-review

2004

Arabidopsis Plasma Membrane Proteomics Identifies Components of Transport, Signal Transduction and Membrane Trafficking

Alexandersson, E., Saalbach, G., Larsson, C. & Kjellbom, P., 2004, In: Plant and Cell Physiology. 45, 11, p. 1543-1556

Research output: Contribution to journal › Article › peer-review

Structural studies on PM28A, an aquaporin from spinach

Törnroth, S., Karlsson, M., Hedfalk, K., Kjellbom, P. & Neutze, R., 2004, In: Biochimica et Biophysica Acta - Bioenergetics. 1658, Supplement 1, p. 187-187

Research output: Contribution to journal › Article › peer-review

2003

Reconstitution of water channel function of an aquaporin overexpressed and purified from Pichia pastoris.

Karlsson, M., Fotiadis, D., Sjövall Larsen, S., Johansson, I., Hedfalk, K., Engel, A. & Kjellbom, P., 2003, In: FEBS Letters. 537, 1-3, p. 68-72

Research output: Contribution to journal › Article › peer-review

2002

Rhizobium colonization induced changes in membrane-bound and soluble hydroxyproline-rich glycoprotein composition in pea.

Olsson, P. A., Kjellbom, P. & Rosendahl, L., 2002, In: Physiologia Plantarum. 114, 4, p. 652-660

Research output: Contribution to journal › Article › peer-review

2001

Structural characterization of two aquaporins isolated from native spinach leaf plasma membranes

Fotiadis, D., Jenö, P., Mini, T., Wirtz, S., Müller, S. A., Fraysse, L., Kjellbom, P. & Engel, A., 2001, In: Journal of Biological Chemistry. 276, 3, p. 1707-1714 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

The complete set of genes encoding major intrinsic proteins in Arabidopsis provides a framework for a new nomenclature for major intrinsic proteins in plants

Johanson, U., Karlsson, M., Johansson, I., Gustavsson, S., Sjövall Larsen, S., Fraysse, L., Weig, A. R. & Kjellbom, P., 2001, In: Plant Physiology. 126, 4, p. 1358-1369

Research output: Contribution to journal › Article › peer-review

Open Access

2000

An abundant TIP expressed in mature highly vacuolated cells

Karlsson, M., Johansson, I., Bush, M., McCann, M. C., Larsson, C. & Kjellbom, P., 2000 Jan, In: Plant Journal. 21, 1, p. 83-90 8 p.

Research output: Contribution to journal › Article › peer-review

1998

Molecular characterization of a new type of receptor-like kinase (wlrk) gene family in wheat

Feuillet, C., Reuzeau, C., Kjellbom, P. & Keller, B., 1998 Aug, In: Plant Molecular Biology. 37, 6, p. 943-953 11 p.

Research output: Contribution to journal › Article › peer-review

Water transport activity of the plasma membrane aquaporin PM28A is regulated by phosphorylation

Johansson, I., Karlsson, M., Shukla, V. K., Chrispeels, M. J., Larsson, C. & Kjellbom, P., 1998 Mar, In: Plant Cell. 10, p. 451-459 9 p.

Research output: Contribution to journal › Article › peer-review

1997

Oxidative cross-linking of plasma membrane arabinogalactan proteins

Kjellbom, P., Snogerup, L., Stöhr, C., Reuzeau, C., McCabe, P. F. & Pennell, R. I., 1997 Feb 5, In: Plant Journal. 12, 5, p. 1189-1196 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

1996

The major integral proteins of spinach leaf plasma membranes are putative aquaporins and are phosphorylated in response to Ca2+ and apoplastic water potential

Johansson, I., Larsson, C., Ek, B. & Kjellbom, P., 1996 Jul, In: Plant Cell. 8, 7, p. 1181-1191 11 p.

Research output: Contribution to journal › Article › peer-review

An agarose gel electrophoresis method for the separation of arabinogalactan proteins.

Stöhr, C., Snogerup, L., Pennell, R. & Kjellbom, P., 1996, In: Plant Journal. 10, 5, p. 943-948

Research output: Contribution to journal › Article › peer-review

1995

Cell-context signalling

Pennell, R. I., Cronk, Q. C. B., Forsberg, L. S., Stöhr, C., Snogerup, L., Kjellbom, P. & McCabe, P. F., 1995, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 350, 1331, p. 87-93 7 p.

Research output: Contribution to journal › Article › peer-review

Identification of cDNA clones encoding vasolin-containing protein and other plant plasma membrane-associated proteins by a general immuno-screening strategy.

Shi, J., Dixon, R. A., Gonzales, R. A., Kjellbom, P. & Bhattacharyya, M. K., 1995, In: Proceedings of the National Academy of Sciences. 92, p. 4457-4461 5 p.

Research output: Contribution to journal › Article › peer-review