Research output per year
Research output per year
Personal profile
Research
Specialized in discovery, development and translational science of mono and bispecific antibodies, with a particular focus on leveraging antigen presenting cells within immuno-oncology. Extensive experience with co-stimulatory receptors, such as CD40 and 4-1BB, as well as with immune checkpoint inhibitors. Taken 4 antibody based drug candidates from invention to clinical development.
Subject classification (UKÄ)
- Engineering and Technology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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First-in-human study of intravenous bispecific CTLA-4 × OX40 antibody (ATOR-1015) in advanced solid malignancies
Ekström-Rydén, V., Carneiro, A., Yachnin, J., Staal Rohrberg, K., Enell Smith, K., Ellmark, P., Løvendahl Eefsen, R. & Ullenhag, G. J., 2026 May, In: ESMO Open. 11, 5, 10 p., 106068.Research output: Contribution to journal › Article › peer-review
Open Access -
REACtiVe-2: phase I evaluation of dendritic cell vaccination and agonistic CD40 therapy following (m)FOLFIRINOX in metastatic pancreatic cancer
Kucukcelebi, S., van 't Land, F. R., van der Burg, S. H., Eskens, F. A. L. M., Homs, M. Y. V., Willemsen, M., Onrust-van Schoonhoven, A., Rozendaal, N. E. M., Fellah, A., Vadgama, D., Moskie, M., Bezemer, K., Doukas, M., van Eijck, C. W. F., Stadhouders, R., de Vos-Geelen, J., van Diepen, A. E., Enninga, I., Meijer, R. & Ambarkhane, S. V. & 4 others, , 2025 Nov 28, In: Nature Communications. 16, 15 p., 10609.Research output: Contribution to journal › Article › peer-review
Open Access -
CD40 agonist mitazalimab with mFOLFIRINOX in untreated metastatic pancreatic cancer: Biomarkers associated with outcomes from OPTIMIZE-1
Van Laethem, J.-L., Geboes, K., Borbath, I., Macarulla Mercade, T., Lambert, A., Cassier, P., Prenen, H., Mitry, E., Blanc, J.-F., Pilla, L., Feliu, J., Rodriguez Garrote, M., Pazo-Cid, R. A., Gallego, I., Smith, K. E., Nordbladh, K., Jimenez, D. G., Ellmark, P., Pico de Coaña, Y. & Ambarkhane, S. V. & 2 others, , 2025 Oct 21, In: Cell Reports Medicine. 6, 10, 102407.Research output: Contribution to journal › Article › peer-review
Open Access -
First-in-human, multicenter, open-label, phase I study of ATOR-1017 (evunzekibart), a 4-1BB antibody, in patients with advanced solid malignancies
Carneiro, A., Hahn, A., Ellmark, P., Enell Smith, K., Schultz, L., Ambarkhane, S., Yachnin, J. & Ullenhag, G. J., 2025 Jan 22, In: Journal for ImmunoTherapy of Cancer. 13Research output: Contribution to journal › Article › peer-review
Open Access -
Antigenic peptide delivery to antigen-presenting cells using a CD40-coiled coil affinity-based platform
Nyesiga, B., Hägerbrand, K., Varas, L., Gjörloff Wingren, A., Ohlin, M., Ellmark, P. & von Schantz, L., 2025, In: Drug delivery. 32, 1, 2486340.Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 1 Active
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Impact of CD40 therapies on the tumor microenvironment
Andersson, H. (Research student), Lindstedt, M. (PI), Ellmark, P. (Assistant supervisor), Sakellariou, C. (Assistant supervisor) & Hägerbrand, K. (Assistant supervisor)
2023/04/01 → 2027/03/31
Project: Research
Activities
- 1 Organisation of workshop/ seminar/ course
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LUCC - Clinical Trials & Diagnostics: Kick off meeting half day
Saal, L. (Organiser), Jerkeman, M. (Organiser), Alkner, S. (Presenter), Heidenblad, M. (Presenter), Ellmark, P. (Presenter) & Jerkeman, M. (Presenter)
2025 Nov 27Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course