Research output per year
Research output per year
Personal profile
Research
In my research I am combining advanced analytical techniques, mainly based on mass spectrometry, to solve challenging biological questions. I am particularly interested in metabolism and metabolic diseases. Metabolism is a complex network involving thousands of enzymes and metabolites - the metabolome. We use metabolomics, i.e. the determination of as many metabolites as possible in a tissue, to study metabolic diseases.
I develop analytical methods based on chromatography and mass spectrometry for analysis of metabolites in various tissue. We also apply these methods in studies aiming to increase our understanding of metabolism. Our main focus is on metabolism in enteroendocrine cells, endocrine cells and in blood, and its association with metabolic diseases, primarily type 2 diabetes mellitus.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
UKÄ subject classification
- Medical and Health Sciences
- Engineering and Technology
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Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Examining functional group-dependent effects on the ionization of lignin monomers using supercritical fluid chromatography/electrospray ionization mass spectrometry
Prothmann, J., Molins-Delgado, D., Braune, A., Sandahl, M., Turner, C. & Spégel, P., 2024 Jul, In: Analytical and Bioanalytical Chemistry. 416, 18, p. 4007-4014 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A protein-rich meal provides beneficial glycemic and hormonal responses as compared to meals enriched in carbohydrate, fat or fiber, in individuals with or without type-2 diabetes
Ekberg, N. R., Catrina, S. B. & Spégel, P., 2024, In: Frontiers in Nutrition. 11, 1395745.Research output: Contribution to journal › Article › peer-review
Open Access -
Genetic deletion of hormone-sensitive lipase in mice reduces cerebral blood flow but does not aggravate the impact of diet-induced obesity on memory
Skoug, C., Rogova, O., Spégel, P., Holm, C. & Duarte, J. M. N., 2024, In: Journal of Neurochemistry. 168, 5, p. 781-800Research output: Contribution to journal › Article › peer-review
Open Access -
Native lignin extraction from soft- and hardwood by green and benign sub/supercritical fluid extraction methodologies
Nardella, F., Prothmann, J., Sandahl, M., Spégel, P., Ribechini, E. & Turner, C., 2023 Jul, In: RSC Advances. 13, 32, p. 21945-21953 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification of a weight loss-associated causal eQTL in MTIF3 and the effects of MTIF3 deficiency on human adipocyte function
Huang, M., Coral, D., Ardalani, H., Spégel, P., Saadat, A., Claussnitzer, M., Mulder, H., Franks, P. W. & Kalamajski, S., 2023 Mar 6, In: eLife. 12:e84168.Research output: Contribution to journal › Article › peer-review
Open Access
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Quantitative fingerprinting of chemical contaminants in pollinating insects – Green unified chromatography and advanced detection techniques supported by machine learning
Turner, C. (PI), Hansson, M. (Researcher), Rigosi, E. (Researcher), Rundlöf, M. (Researcher), Sandahl, M. (Researcher) & Spégel, P. (Researcher)
FORMAS, The Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning
2023/01/01 → 2025/12/31
Project: Research
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Metabolic signaling from the liver in type 2 diabetes
Kaldis, P. (PI) & Spégel, P. (Researcher)
2022/01/01 → 2024/12/31
Project: Research
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iENT: Neuroenvironmental toxicity: a new synergistic approach to quantify acute and chronic sublethal effects of commonly-used pesticides on insects
Rigosi, E. (PI), Turner, C. (CoI), Rundlöf, M. (CoI), Herbertsson, L. (CoI), O'carroll, D. (CoI), Stensmyr, M. (CoI), Spégel, P. (CoI), Palmer, S. (Research student), Miegel, E. (Research student), Rönnau, S. (Research student), Davila, N. (Research student) & Fathi, M. (Research assistant)
2022/01/01 → 2027/12/31
Project: Research
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Adipocyte plasma membrane composition and its role in insulin sensitivity
Kopietz, F. (Researcher), Stenkula, K. (PI) & Spégel, P. (PI)
2021/12/01 → …
Project: Research
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ChemFreeGarden: ChemFreeGarden: Reducing chemicals in urban private gardens to promote biodiversity, health and ecosystem services
Hansson, M. (Researcher), Molbert, N. (Researcher), Turner, C. (Researcher), Spégel, P. (Researcher), Molins Delgado, D. (Research assistant), Öckinger, E. (Researcher), van Praagh, M. (Researcher) & Alkan Olsson, J. (Researcher)
2020/01/01 → 2026/12/31
Project: Research
Activities
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DPLU Postgraduate Diabetes Course 2021
King, B. (Organiser), Bacos, K. (Organiser), Spégel, P. (Organiser) & Filipsson, K. (Organiser)
2021 Oct 25 → 2021 Oct 29Activity: Participating in or organising an event › Participation in workshop/ seminar/ course
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Exodiab mini-symposium
Spégel, P. (Invited speaker), King, B. (Invited speaker), Salehi, S. A. (Invited speaker), Fex, M. (Invited speaker) & Gomez, M. (Chair)
2018 Nov 27Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
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Världsdiabetesdagen i Skåne 2018
Landén, T. (Chair), Löndahl, F. (Invited speaker), Lindberg, A. (Invited speaker), Bällsten, Å. (Invited speaker), Vigård, T. (Invited speaker), Elding Larsson, H. (Invited speaker), Spégel, P. (Invited speaker), Brunkwall, L. (Invited speaker), Virdeborn, C. (Invited speaker), Melander, O. (Invited speaker), Bennet, L. (Invited speaker), Rosman, S. (Invited speaker), Artner, I. (Invited speaker), Blom-Nilsson, U. (Organiser) & Liedholm, S. (Organiser)
2018 Nov 10Activity: Participating in or organising an event › Organisation of public lecture/debate/seminar
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Diabetes research day
Krus, U. (Organiser), Blom-Nilsson, U. (Organiser), Spégel, P. (Organiser), Esguerra, J. (Organiser), Todd, J. A. (Invited speaker), Duarte, J. (Invited speaker), Ahlqvist, E. (Invited speaker), Brunkwall, L. (Invited speaker) & Lira Ruas, J. (Invited speaker)
2018 Feb 13Activity: Participating in or organising an event › Organisation of conference
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Post graduate course in diabetes research
Krus, U. (Organiser), Spégel, P. (Organiser), Esguerra, J. (Organiser), Filipsson, K. (Organiser), Cilio, C. (Invited speaker), Nilsson, P. (Invited speaker), Wierup, N. (Invited speaker), Mulder, H. (Invited speaker), Groop, L. (Invited speaker), Gustavsson, C. (Invited speaker), Shaat, N. (Invited speaker), Göransson, O. (Invited speaker), Degerman, E. (Invited speaker), Sandberg, A. (Invited speaker), Renström, E. (Invited speaker), V. Varga, T. (Invited speaker), Hansson, O. (Invited speaker), Ling, C. (Invited speaker), Berger, K. (Invited speaker), Skog, O. (Invited speaker), Eliasson, L. (Invited speaker), Blixt, M. (Invited speaker), Fagher, K. (Invited speaker), Artner, I. (Invited speaker), Edsfeldt, A. (Invited speaker), Löndahl, M. (Invited speaker) & Strevens, H. (Invited speaker)
2017 Apr 3 → 2017 Apr 7Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course
Prizes and Distinction
Infrastructure
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KILU/CAS Mass spectrometry infrastructure
Krais, A. (Manager) & Ellervik, U. (Manager)
Centre for Analysis and SynthesisInfrastructure
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