Pontus Dunér

Search results

• 2023

  Ablation of GPR56 Causes β-Cell Dysfunction by ATP Loss through Mistargeting of Mitochondrial VDAC1 to the Plasma Membrane

  Mohammad Al-Amily, I., Sjögren, M., Duner, P., Tariq, M., Wollheim, C. B. & Salehi, A., 2023, In: Biomolecules. 13, 3, 557.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Voltage-Dependent Anion Channel 1 100%
  • Ablation 66%
  • G-Protein-Coupled Receptors 58%
  • Adenosine Triphosphate 44%
  • Cell Membrane 42%

• Transforming growth factor-β2 is associated with atherosclerotic plaque stability and lower risk for cardiovascular events

  Edsfeldt, A., Singh, P., Matthes, F., Tengryd, C., Cavalera, M., Bengtsson, E., Dunér, P., Volkov, P., Karadimou, G., Gisterå, A., Orho-Melander, M., Nilsson, J., Sun, J. & Gonçalves, I., 2023 Aug, In: Cardiovascular Research. 119, 11, p. 2061-2073

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Transforming Growth Factors 100%
  • Atherosclerotic Plaques 99%
  • Transforming Growth Factor beta 87%
  • Protein Isoforms 25%
  • Chemokine CCL2 14%
• 2021

  Antibodies against apoB100 peptide 210 inhibit atherosclerosis in apoE^-/- mice

  Dunér, P., Mattisson, I. Y., Fogelstrand, P., Glise, L., Ruiz, S., Farina, C., Borén, J., Nilsson, J. & Bengtsson, E., 2021 Dec 1, In: Scientific Reports. 11, 1, 9022.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apolipoprotein B-100 100%
  • Apolipoproteins E 73%
  • PADRE 45 57%
  • Atherosclerosis 56%
  • oxidized low density lipoprotein 55%
• 2020

  An osteopontin-derived peptide inhibits human hair growth at least in part by decreasing fibroblast growth factor-7 production in outer root sheath keratinocytes

  Alam, M., Bertolini, M., Gherardini, J., Keren, A., Ponce, L., Chéret, J., Alenfall, J., Dunér, P., Hultgårdh, A., Gilhar, A. & Paus, R., 2020 Jun, In: British Journal of Dermatology. 182, 6, p. 1404-1414 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Fibroblast Growth Factor 7 100%
  • Osteopontin 82%
  • Hair 68%
  • Keratinocytes 67%
  • Peptides 44%

• Inhibitory effect of UDP-glucose on cAMP generation and insulin secretion

  Parandeh, F., Amisten, S., Verma, G., Mohammed Al-Amily, I., Dunér, P. & Salehi, A., 2020, In: The Journal of biological chemistry. 295, 45, p. 15245-15252 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Uridine Diphosphate Glucose 100%
  • Insulin Derivative 68%
  • Insulin Secretion 66%
  • Glucose 49%
  • Type 2 Diabetes Mellitus 15%

• Orphan G-protein coupled receptor 183 (GPR183) potentiates insulin secretion and prevents glucotoxicity-induced β-cell dysfunction

  Taneera, J., Mohammed, I., Mohammed, A. K., Hachim, M., Dhaiban, S., Malek, A., Dunér, P., Elemam, N. M., Sulaiman, N., Hamad, M. & Salehi, A., 2020, In: Molecular and Cellular Endocrinology. 499, 110592.

  Research output: Contribution to journal › Article › peer-review

  • Insulin Derivative 100%
  • G-Protein-Coupled Receptors 98%
  • Insulin Secretion 97%
  • Microarrays 52%
  • Agonist 46%

• Syndecan-4 Protects the Heart From the Profibrotic Effects of Thrombin-Cleaved Osteopontin

  Herum, K. M., Romaine, A., Wang, A., Melleby, A. O., Strand, M. E., Pacheco, J., Braathen, B., Dunér, P., Tønnessen, T., Lunde, I. G., Sjaastad, I., Brakebusch, C., McCulloch, A. D., Gomez, M. F., Carlson, C. R. & Christensen, G., 2020 Feb 4, In: Journal of the American Heart Association. 9, 3, p. e013518

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Syndecan-4 100%
  • Osteopontin 73%
  • Thrombin 61%
  • Heart 40%
  • Fibrosis 13%

• The proteoglycan mimecan is associated with carotid plaque vulnerability and increased risk of future cardiovascular death

  Tengryd, C., Nielsen, S. H., Cavalera, M., Bengtsson, E., Genovese, F., Karsdal, M., Dunér, P., Orho-Melander, M., Nilsson, J., Edsfeldt, A. & Gonçalves, I., 2020 Nov, In: Atherosclerosis. 313, p. 88-95 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Proteoglycans 100%
  • Macrophages 64%
  • Atherosclerotic Plaques 47%
  • Matrix Metalloproteinases 43%
  • Smooth Muscle Myocytes 40%
• 2019

  Activation of immune responses against the basement membrane component collagen type IV does not affect the development of atherosclerosis in ApoE-deficient mice

  Vallejo, J., Dunér, P., To, F., Engelbertsen, D., Gonçalves, I., Nilsson, J. & Bengtsson, E., 2019 Apr 12, In: Scientific Reports. 9, 1, 5964.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Collagen Type IV 100%
  • Apolipoproteins E 88%
  • Atherosclerosis 67%
  • Collagen Type XII 44%
  • Autoantibodies 44%

• Associations of Interleukin-5 With Plaque Development and Cardiovascular Events

  Knutsson, A., Björkbacka, H., Dunér, P., Engström, G., Binder, C. J., Nilsson, A. H. & Nilsson, J., 2019, In: JACC: Basic to Translational Science. 4, 8, p. 891-902 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Interleukin-5 100%
  • Apolipoproteins E 19%
  • Immunoglobulin M 15%
  • Diet 12%
  • Stroke 12%

• Cartilage Oligomeric Matrix Protein Associates With a Vulnerable Plaque Phenotype in Human Atherosclerotic Plaques

  Hultman, K., Edsfeldt, A., Björkbacka, H., Dunér, P., Sundius, L., Nitulescu, M., Persson, A., Boyle, J. J., Nilsson, J., Hultgårdh-Nilsson, A., Bengtsson, E. & Gonçalves, I., 2019, In: Stroke. 50, 11, p. 3289-3292 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Cartilage Oligomeric Matrix Protein 100%
  • Atherosclerotic Plaques 68%
  • Phenotype 39%
  • human COMP protein 13%
  • Smooth Muscle Myocytes 11%

• ILC2 transfers to apolipoprotein E deficient mice reduce the lipid content of atherosclerotic lesions

  Mantani, P. T., Dunér, P., Ljungcrantz, I., Nilsson, J., Björkbacka, H. & Fredrikson, G. N., 2019 Dec 10, In: BMC Immunology. 20, 47.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • NK Cell Lectin-Like Receptors 100%
  • Apolipoproteins E 96%
  • Lipids 59%
  • Interleukin-17 57%
  • Phosphorylcholine 47%

• The functional impact of G protein-coupled receptor 142 (Gpr142) on pancreatic β-cell in rodent

  Al-Amily, I. M., Dunér, P., Groop, L. & Salehi, A., 2019, In: Pflügers Archiv. 471, 4, p. 633-645

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Insulin Derivative 100%
  • G-Protein-Coupled Receptors 98%
  • Rodentia 81%
  • Agonist 56%
  • Insulin Secretion 24%
• 2018

  Activation of imidazoline receptor I₂, and improved pancreatic β-cell function in human islets

  Amisten, S., Duner, P., Asplund, O., Mohammed Al-Amily, I., Groop, L. & Salehi, A., 2018 Sept, In: Journal of Diabetes and its Complications. 32, 9, p. 813-818

  Research output: Contribution to journal › Article › peer-review

  • BL 11282 100%
  • imidazoline receptor 2 78%
  • Insulin Secretion 18%
  • Glucose 15%
  • RNA Sequence Analysis 13%

• Hyperglycemia does not affect tissue repair responses in shear stress-induced atherosclerotic plaques in ApoE-/-mice

  Hsiung, S., Knutsson, A., Vallejo, J., Dunér, P., Heinonen, S. E., Jönsson-Rylander, A. C., Bengtsson, E., Nilsson, J. & Hultgårdh-Nilsson, A., 2018 Dec 1, In: Scientific Reports. 8, 1, 7530.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apolipoproteins E 100%
  • Atherosclerotic Plaques 98%
  • Hyperglycemia 85%
  • Smooth Muscle Myocytes 41%
  • Scleroproteins 38%

• Interleukin-25 (IL-25) has a protective role in atherosclerosis development in the aortic arch in mice

  Mantani, P. T., Dunér, P., Bengtsson, E., Ljungcrantz, I., Sundius, L., To, F., Nilsson, J., Björkbacka, H. & Fredrikson, G. N., 2018 Jan 1, In: Journal of Biological Chemistry. 293, 18, p. 6791-6801 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Interleukin-17 100%
  • Thoracic Aorta 94%
  • Protective 78%
  • Atherosclerosis 76%
  • Apolipoproteins E 36%
• 2017

  ADAMTS-7 is associated with a high-risk plaque phenotype in human atherosclerosis

  Bengtsson, E., Hultman, K., Dunér, P., Asciutto, G., Almgren, P., Orho-Melander, M., Melander, O., Nilsson, J., Hultgårdh, A. & Gonçalves, I., 2017 Dec 1, In: Scientific Reports. 7, 1, 3753.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Atherosclerosis 100%
  • Phenotype 74%
  • Thrombospondin 1 55%
  • Disintegrins 54%
  • Neointima 53%

• Autoantibodies against aldehyde-modified collagen type IV are associated with risk of development of myocardial infarction

  Vallejo, J., Dunér, P., Fredrikson, G. N., Nilsson, J. & Bengtsson, E., 2017 Dec, In: Journal of Internal Medicine. 282, 6, p. 496-507

  Research output: Contribution to journal › Article › peer-review

  • Aldehydes 100%
  • Collagen Type IV 99%
  • Malondialdehyde 81%
  • Autoantibodies 77%
  • Myocardial Infarction 60%

• β-Sarcoglycan Deficiency Reduces Atherosclerotic Plaque Development in ApoE-Null Mice

  Murugesan, V., Degerman, E., Knutsson, A., Dunér, P., Holmén-Pålbrink, A-K., Hultgårdh, A. & Rauch, U., 2017 Jul 29, In: Journal of Vascular Research. 54, p. 235-245

  Research output: Contribution to journal › Article › peer-review

  • Sarcoglycans 100%
  • Apolipoproteins E 69%
  • Atherosclerotic Plaques 67%
  • Dystrophin 23%
  • Smooth Muscle Myocytes 16%
• 2016

  Adhesion G protein-coupled receptor G1 (ADGRG1/GPR56) and pancreatic β-cell function

  Dunér, P., Mohammed, I., Soni, A., Asplund, O., Safi, F., Storm, P., Groop, L., Amisten, S. & Salehi, S. A., 2016 Dec 1, In: Journal of Clinical Endocrinology and Metabolism. 101, 12, p. 4637-4645 9 p.

  Research output: Contribution to journal › Article › peer-review

  • RNA Sequencing 100%
  • Insulin Derivative 61%
  • G-Protein-Coupled Receptors 60%
  • Collagen 57%
  • Pharmacologic Agent 43%

• Glucose-Dependent Insulinotropic Polypeptide (GIP) Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.

  Berglund, L., Lyssenko, V., Ladenvall, C., Kotova, O., Edsfeldt, A., Pilgaard, K., Alkayyali, S., Brøns, C., Forsblom, C., Jonsson, A., Zetterqvist, A., Nitulescu, M., Ruiz McDavitt, C., Dunér, P., Stancáková, A., Kuusisto, J., Ahlqvist, E., Lajer, M., Tarnow, L., Madsbad, S., & 13 othersRossing, P., Kieffer, T. J., Melander, O., Orho-Melander, M., Nilsson, P., Groop, P-H., Vaag, A., Lindblad, B., Gottsäter, A., Laakso, M., Goncalves, I., Groop, L. & Gomez, M., 2016, In: Diabetes. 65, 1, p. 239-254

  Research output: Contribution to journal › Article › peer-review

  File

  • Cyclic AMP Response Element-Binding Protein 100%
  • Osteopontin 94%
  • Endothelin-1 85%
  • gastric inhibitory polypeptide receptor 79%
  • Peptides 50%
  283 Downloads (Pure)

• High levels of cathepsin D and cystatin B are associated with increased risk of coronary events.

  Goncalves, I., Hultman, K., Dunér, P., Edsfeldt, A., Hedblad, B., Nordin Fredrikson, G., Björkbacka, H., Nilsson, J. & Bengtsson, E., 2016, In: Open Heart. 3, 1, p. e000353

  Research output: Contribution to journal › Article › peer-review

  • Cystatin B 100%
  • Cathepsin D 76%
  • Rupture 49%
  • Peptide Hydrolases 49%
  • Cathepsins 39%

• High Plasma Levels of Galectin-3 Are Associated with Increased Risk for Stroke after Carotid Endarterectomy.

  Edsfeldt, A., Bengtsson, E., Asciutto, G., Dunér, P., Björkbacka, H., Nordin Fredrikson, G., Nilsson, J. & Goncalves, I., 2016, In: Cerebrovascular Diseases. 41, 3-4, p. 199-203

  Research output: Contribution to journal › Article › peer-review

  • Galectin 3 100%
  • Carotid Endarterectomy 88%
  • Stroke 51%
  • Carotid Artery Diseases 23%

• Proinflammatory Role of Sphingolipids and Glycosphingolipids in the Human Atherosclerotic Plaque

  Edsfeldt, A., Dunér, P., Ståhlman, M., Mollet, I. G., Asciutto, G., GRUFMAN, ANNA. HELENA. MARIA., Nitulescu, M., Persson, A. F., Fisher, R. M., Melander, O., Orho-Melander, M., Borén, J., Nilsson, J. & Gonçalves, I., 2016, In: Arteriosclerosis, Thrombosis and Vascular Biology. 36, 6, p. 1132-1140

  Research output: Contribution to journal › Article › peer-review

  • Glycosphingolipids 100%
  • Sphingolipids 93%
  • Atherosclerotic Plaques 79%
  • CDw17 antigen 45%
  • Glucosylceramides 41%
• 2015

  Autoantibodies against basement membrane collagen type IV are associated with myocardial infarction

  McLeod, O., Dunér, P., Samnegård, A., Tornvall, P., Nilsson, J., Hamsten, A. & Bengtsson, E., 2015 Mar 1, In: IJC Heart and Vasculature. 6, p. 42-47 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Collagen Type IV 100%
  • Autoantibodies 77%
  • Myocardial Infarction 60%
  • Aldehydes 40%
  • Immunoglobulin G 25%

• Dystrophin deficiency reduces atherosclerotic plaque development in ApoE-null mice.

  Shami, A., Knutsson, A., Dunér, P., Rauch, U., Bengtsson, E., Tengryd, C., Murugesan, V., Durbeej-Hjalt, M., Goncalves, I., Nilsson, J. & Hultgårdh, A., 2015, In: Scientific Reports. 5, 13904.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dystrophin 100%
  • Apolipoproteins E 85%
  • Atherosclerotic Plaques 83%
  • Inbred mdx Mouse 55%
  • Smooth Muscle Myocytes 35%

• Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes.

  Goncalves, I., Bengtsson, E., Colhoun, H. M., Shore, A. C., Palombo, C., Natali, A., Edsfeldt, A., Dunér, P., Nordin Fredrikson, G., Björkbacka, H., Östling, G., Aizawa, K., Casanova, F., Persson, M., Gooding, K., Strain, D., Kahn, F., Looker, H. C., Adams, F., Belch, J., & 6 othersPinnoli, S., Venturi, E., Kozakova, M., Gan, L-M., Schnecke, V. & Nilsson, J., 2015, In: Arteriosclerosis, Thrombosis and Vascular Biology. 35, 7, p. 1723-1731

  Research output: Contribution to journal › Article › peer-review

  • Matrix Metalloproteinase 12 100%
  • Matrix Metalloproteinases 61%
  • Atherosclerosis 51%
  • Type 2 Diabetes Mellitus 48%
  • Cardiovascular Diseases 46%

• High Plasma Levels of Heparin-Binding Epidermal Growth Factor Are Associated With a More Stable Plaque Phenotype and Reduced Incidence of Coronary Events.

  Rattik, S., Wigren, M., Björkbacka, H., Nordin Fredrikson, G., Hedblad, B., Siegbahn, A., Bengtsson, E., Schiopu, A., Edsfeldt, A., Dunér, P., Grufman, H., Goncalves, I. & Nilsson, J., 2015, In: Arteriosclerosis, Thrombosis and Vascular Biology. 35, 1, p. 222-228

  Research output: Contribution to journal › Article › peer-review

  • Atherosclerotic Plaques 100%
  • Epidermal Growth Factor 93%
  • Heparin 86%
  • Smooth Muscle Myocytes 84%
  • Phenotype 57%

• IL-25 Inhibits Atherosclerosis Development in Apolipoprotein E Deficient Mice.

  Mantani, P., Dunér, P., Bengtsson, E., Alm, R., Ljungcrantz, I., Söderberg, I., Sundius, L., To, F., Nilsson, J., Björkbacka, H. & Nordin Fredrikson, G., 2015, In: PLoS ONE. 10, 1, e0117255.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Health Services Needs and Demand 100%
  • Apolipoproteins E 95%
  • Autoimmune Diseases 77%
  • Immunity 73%
  • Atherosclerosis 72%
  265 Downloads (Pure)

• Increased aldehyde-modification of collagen type IV in symptomatic plaques - A possible cause of endothelial dysfunction.

  Dunér, P., Goncalves, I., Grufman, H., Edsfeldt, A., To, F., Nitulescu, M., Nilsson, J. & Bengtsson, E., 2015, In: Atherosclerosis. 240, 1, p. 26-32

  Research output: Contribution to journal › Article › peer-review

  File

  • Aldehydes 100%
  • Collagen Type IV 99%
  • oxidized low density lipoprotein 83%
  • Apolipoproteins 32%
  • Extracellular Matrix Proteins 31%
  205 Downloads (Pure)

• Low elastin content of carotid plaques is associated with increased risk of ipsilateral stroke.

  Asciutto, G., Dias, N., Edsfeldt, A., Nitulescu, M., Persson, A., Nilsson, M. MN., Dunér, P., Nilsson, J. & Goncalves, I., 2015, In: PLoS ONE. 10, 3, e0121086.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Matrix Metalloproteinase 3 100%
  • Matrix Metalloproteinase 1 96%
  • Elastin 92%
  • Atherosclerotic Plaques 82%
  • Connective Tissue 74%
  157 Downloads (Pure)
• 2014

  Impaired Fibrous Repair: A Possible Contributor to Atherosclerotic Plaque Vulnerability in Patients With Type II Diabetes.

  Edsfeldt, A., Goncalves, I., Grufman, H., Nitulescu, M., Dunér, P., Bengtsson, E., Mollet, I., Persson, A., Nilsson, M. MN., Orho-Melander, M., Melander, O., Björkbacka, H. & Nilsson, J., 2014, In: Arteriosclerosis, Thrombosis and Vascular Biology. 34, 9, p. 2143-2150

  Research output: Contribution to journal › Article › peer-review

  • Atherosclerotic Plaques 100%
  • Diabetes Mellitus 76%
  • Type 2 Diabetes Mellitus 71%
  • Inflammation 37%

• Plasma S100A8/A9 Correlates With Blood Neutrophil Counts, Traditional Risk Factors, and Cardiovascular Disease in Middle-Aged Healthy Individuals.

  Cotoi, O., Dunér, P., Ko, N., Hedblad, B., Nilsson, J., Björkbacka, H. & Schiopu, A., 2014, In: Arteriosclerosis, Thrombosis and Vascular Biology. 34, 1, p. 202

  Research output: Contribution to journal › Article › peer-review

  File

  • Alarmins 100%
  • Carotid Artery Diseases 80%
  • Monocytes 55%
  • Atherosclerosis 53%
  • Neutrophils 52%
  265 Downloads (Pure)
• 2013

  Inhibition of nuclear factor of activated T-cells (NFAT) suppresses accelerated atherosclerosis in diabetic mice.

  Zetterqvist, A., Berglund, L., Blanco, F., Garcia Vaz, E., Wigren, M., Dunér, P., Dutius Andersson, A-M., To, F., Spégel, P., Nilsson, J., Bengtsson, E. & Gomez, M., 2013, In: PLoS ONE. 8, 6, e65020.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • NFATC Transcription Factors 100%
  • Atherosclerosis 60%
  • Osteopontin 44%
  • Peripheral Vascular Diseases 44%
  • Hyperglycemia 34%
  342 Downloads (Pure)
• 2012

  Increased Inflammation in Atherosclerotic Lesions of Diabetic Akita-LDLr(-/-) Mice Compared to Nondiabetic LDLr(-/-) Mice.

  Engelbertsen, D., To, F., Dunér, P., Kotova, O., Söderberg, I., Alm, R., Gomez, M., Nilsson, J. & Bengtsson, E., 2012, In: Experimental Diabetes Research. 2012, Nov.,28, 176162.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Mouse 100%
  • Inflammation 90%
  • Lesion 70%
  • Atherosclerosis 32%
  • Plasma 27%
  169 Downloads (Pure)

• Plasma fibronectin deficiency impedes atherosclerosis progression and fibrous cap formation

  Rohwedder, I., Montanez, E., Beckmann, K., Bengtsson, E., Dunér, P., Nilsson, J., Soehnlein, O. & Faessler, R., 2012, In: EMBO Molecular Medicine. 4, 7, p. 564-576

  Research output: Contribution to journal › Article › peer-review

  • Fibronectins 100%
  • Atherosclerosis 82%
  • Blood Vessels 44%
  • Rupture 43%
  • Atherogenic Diet 37%
• 2011

  Evidence for a role of regulatory T cells in mediating the atheroprotective effect of apolipoprotein B peptide vaccine.

  Wigren, M., Kolbus, D., Dunér, P., Ljungcrantz, I., Söderberg, I., Björkbacka, H., Nordin Fredrikson, G. & Nilsson, J., 2011, In: Journal of Internal Medicine. 269, p. 546-556

  Research output: Contribution to journal › Article › peer-review

  • Subunit Vaccines 100%
  • Apolipoproteins B 91%
  • Regulatory T-Lymphocytes 82%
  • Atherosclerosis 66%
  • Autoimmunity 34%

• Immunization of apoE-/- mice with aldehyde-modified fibronectin inhibits the development of atherosclerosis.

  Dunér, P., To, F., Beckmann, K., Björkbacka, H., Nordin Fredrikson, G., Nilsson, J. & Bengtsson, E., 2011, In: Cardiovascular Research. 91, 3, p. 528-536

  Research output: Contribution to journal › Article › peer-review

  File

  • Aldehydes 100%
  • Apolipoproteins E 88%
  • Fibronectins 82%
  • Malondialdehyde 81%
  • Immunization 70%
  177 Downloads (Pure)

• Pleiotropic Effects of GIP on Islet Function Involve Osteopontin

  Lyssenko, V., Eliasson, L., Kotova, O., Pilgaard, K., Wierup, N., Salehi, S. A., Wendt, A., Jonsson, A., De Marinis, Y. Z., Berglund, L., Taneera, J., Balhuizen, A., Hansson, O., Osmark, P., Dunér, P., Brons, C., Stancakova, A., Kuusisto, J., Bugliani, M., Saxena, R., & 19 othersAhlqvist, E., Kieffer, T. J., Tuomi, T., Isomaa, B., Melander, O., Sonestedt, E., Orho-Melander, M., Nilsson, P., Bonetti, S., Bonadonna, R., Miccoli, R., DelPrato, S., Marchetti, P., Madsbad, S., Poulsen, P., Vaag, A., Laakso, M., Gomez, M. & Groop, L., 2011, In: Diabetes. 60, 9, p. 2424-2433

  Research output: Contribution to journal › Article › peer-review

  • Osteopontin 100%
  • Peptides 53%
  • Glucose 53%
  • gastric inhibitory polypeptide receptor 51%
  • Insulin Secretion 38%
• 2010

  Fc{gamma}RIIB Inhibits the Development of Atherosclerosis in Low-Density Lipoprotein Receptor-Deficient Mice.

  Zhao, M., Wigren, M., Dunér, P., Kolbus, D., Berg, K., Björkbacka, H., Nilsson, J. & Nordin Fredrikson, G., 2010, In: Journal of Immunology. 184, 5, p. 2253-2260

  Research output: Contribution to journal › Article › peer-review

  • Fc gamma receptor IIB 100%
  • LDL Receptors 55%
  • Atherosclerosis 38%
  • IgG Receptors 21%
  • Thoracic Aorta 15%

• Immune responses against aldehyde-modified laminin accelerate atherosclerosis in Apoe(-/-) mice.

  Dunér, P., To, F., Berg, K., Alm, R., Björkbacka, H., Engelbertsen, D., Nordin Fredrikson, G., Nilsson, J. & Bengtsson, E., 2010, In: Atherosclerosis. 212, 2, p. 457-465

  Research output: Contribution to journal › Article › peer-review

  File

  • Aldehydes 100%
  • Laminin 91%
  • Apolipoproteins E 88%
  • Malondialdehyde 74%
  • Atherosclerosis 67%
  171 Downloads (Pure)
• 2009

  Atheroprotective Effects of Alum Are Associated With Capture of Oxidized LDL Antigens and Activation of Regulatory T Cells.

  Wigren, M., Kolbus, D., Dunér, P., Berg, K., Björkbacka, H., Bengtsson, E., Nordin Fredrikson, G. & Nilsson, J., 2009, In: Circulation Research. 104, p. E62-E70

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • aluminum sulfate 100%
  • oxidized low density lipoprotein 73%
  • Regulatory T-Lymphocytes 72%
  • Apolipoproteins E 55%
  • Antigens 46%

• Evidence Of A Role Of T Regulatory Cells Mediating Atheroprotection By APO B 100 Peptide Immunization

  Wigren, M., Kolbus, D., Dunér, P., Björkbacka, H., Nordin Fredrikson, G. & Nilsson, J., 2009, In: Atherosclerosis Supplements. 10, 2, p. e885-e885

  Research output: Contribution to journal › Published meeting abstract › peer-review

• Immune responses against fibronectin modified by lipoprotein oxidation and their association with cardiovascular disease.

  Dunér, P., To, F., Alm, R., Goncalves, I., Nordin Fredrikson, G., Hedblad, B., Berglund, G., Nilsson, J. & Bengtsson, E., 2009, In: Journal of Internal Medicine. Feb 14., p. 593-603

  Research output: Contribution to journal › Article › peer-review

  • Aldehydes 100%
  • Fibronectins 82%
  • Lipoproteins 79%
  • Cardiovascular Diseases 60%
  • low density lipoprotein inhibitor 34%

• Immune Responses Aginst Aldehyde Modified Extracellular Matrix in Atherosclerosis

  Dunér, P., 2009, Department of Clinical Sciences, Lund University. 113 p.

  Research output: Thesis › Doctoral Thesis (compilation)

  File

  • Aldehydes 100%
  • Malondialdehyde 81%
  • Extracellular Matrix 70%
  • Atherosclerosis 67%
  • oxidized low density lipoprotein 33%
  347 Downloads (Pure)
• 2007

  A constitutive endogenous osteopontin production is important for macrophage function and differentiation.

  Nyström, T., Dunér, P. & Hultgårdh, A., 2007, In: Experimental Cell Research. 313, 6, p. 1149-1160

  Research output: Contribution to journal › Article › peer-review

  • Osteopontin 100%
  • Macrophages 59%
  • Phenotype 13%
  • Scavenger Receptors 9%
  • Apoptosis 9%