Research output per year
Research output per year
- 1 - 50 out of 54 results
Search results
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2025
Copy number signatures in cervical samples enable early detection of high-grade serous ovarian carcinoma
Veerla, S., Martin de la Fuente, L., Li, M., Tang, G., Ebbesson, A., D'Incalci, M., Marchini, S., Mannarino, L., Måsbäck, A., Malander, S., Kannisto, P. & Hedenfalk, I., 2025 May 23.Research output: Contribution to conference › Poster › peer-review
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Global Transcriptional Complexity of Estrogen Receptor Low Positive Breast Cancers in a Prospective Swedish Population-based SCAN-B Cohort
Kimbung, S., Veerla, S., Muhammad, K., Ehinger, A., Vallon-Christersson, J., Malmberg, M. & Loman, N., 2025 Apr 14, (E-pub ahead of print) In: Clinical cancer research : an official journal of the American Association for Cancer Research.Research output: Contribution to journal › Article › peer-review
Open Access -
The DNA methylation landscape of primary triple-negative breast cancer
Aine, M., Nacer, D. F., Arbajian, E., Veerla, S., Karlsson, A., Häkkinen, J., Johansson, H. J., Rosengren, F., Vallon-Christersson, J., Borg, Å. & Staaf, J., 2025 Mar 28, In: Nature Communications. 16, p. 1-23 3041.Research output: Contribution to journal › Article › peer-review
Open Access -
Tertiary lymphoid structures in high-grade serous tubo-ovarian carcinoma: anatomical site matters
Westbom-Fremer, S., Tran, L., Ebbesson, A., Martin de la Fuente, L., Jönsson, J.-M., Kannisto, P., Veerla, S. & Hedenfalk, I., 2025 Jan 3, In: Cancer Immunology Immunotherapy. 74, 56.Research output: Contribution to journal › Article › peer-review
Open Access -
Genomic characterization of the HER2-enriched intrinsic molecular subtype in primary ER-positive HER2-negative breast cancer
Hohmann, L., Sigurjonsdottir, K., Campos, A. B., Nacer, D. F., Veerla, S., Rosengren, F., Reddy, P. T., Häkkinen, J., Nordborg, N., Vallon-Christersson, J., Memari, Y., Black, D., Bowden, R., Davies, H. R., Borg, Å., Nik-Zainal, S. & Staaf, J., 2025, In: Nature Communications. 16, p. 1-17 2208.Research output: Contribution to journal › Article › peer-review
Open Access -
2024
A Versatile and Upgraded Version of the LundTax Classification Algorithm Applied to Independent Cohorts
Cotillas, E. A., Bernardo, C., Veerla, S., Liedberg, F., Sjödahl, G. & Eriksson, P., 2024 Dec, In: Journal of Molecular Diagnostics. 26, 12, p. 1081-1101 21 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Tumor purity estimated from bulk DNA methylation can be used for adjusting beta values of individual samples to better reflect tumor biology
Sasiain, I., Nacer, D. F., Aine, M., Veerla, S. & Staaf, J., 2024 Dec, In: NAR Genomics and Bioinformatics. 6, 4, lqae146.Research output: Contribution to journal › Article › peer-review
Open Access -
Kataegis in clinical and molecular subgroups of primary breast cancer
Veerla, S. & Staaf, J., 2024 Apr 24, In: npj Breast Cancer. 10, 1, p. 1-13 32.Research output: Contribution to journal › Article › peer-review
Open Access -
The role of extracellular vesicle fusion with target cells in triggering systemic inflammation
Papareddy, P., Tapken, I., Kroh, K., Varma Bhongir, R. K., Rahman, M., Baumgarten, M., Cim, E. I., Györffy, L., Smeds, E., Neumann, A., Veerla, S., Olinder, J., Thorlacus, H., Ryden, C., Bartakova, E., Holub, M. & Herwald, H., 2024 Feb 7, In: Nature Communications. 15, 1150.Research output: Contribution to journal › Article › peer-review
Open Access -
Genomic alterations in ovarian endometriosis and subsequently diagnosed ovarian carcinoma
Linder, A., Westbom-Fremer, S., Mateoiu, C., Olsson Widaja, A., Österlund, T., Veerla, S., Ståhlberg, A., Ulfenborg, B., Hedenfalk, I. & Sundfeldt, K., 2024, In: Human Reproduction. 39, 5, p. 1141-1154Research output: Contribution to journal › Article › peer-review
Open Access -
Kataegis in clinical and molecular subgroups of primary breast cancer
Veerla, S. & Staaf, J., 2024.Research output: Contribution to conference › Poster › peer-review
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2023
CD169+ Macrophages in Primary Breast Tumors Associate with Tertiary Lymphoid Structures, Tregs and a Worse Prognosis for Patients with Advanced Breast Cancer
Briem, O., Källberg, E., Kimbung, S., Veerla, S., Stenström, J., Hatschek, T., Hagerling, C., Hedenfalk, I. & Leandersson, K., 2023, In: Cancers. 15, 4, 1262.Research output: Contribution to journal › Article › peer-review
Open Access -
Deciphering the normal-like molecular subtype of breast cancer
Veerla, S., Kimbung, S., Vallon-Christersson, J., Ebbesson, A. & Hedenfalk, I., 2023.Research output: Contribution to conference › Poster
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Perturbation and stability of PAM50 subtyping in population-based primary invasive breast cancer
Veerla, S., Hohmann, L., Nacer, D. F., Vallon-Christersson, J. & Staaf, J., 2023, In: npj Breast Cancer. 9, 1, 83.Research output: Contribution to journal › Article › peer-review
Open Access -
Perturbation and stability of PAM50 subtyping in population-based primary invasive breast cancer
Veerla, S., Hohmann, L., Nacer, D. F., Vallon-Christersson, J. & Staaf, J., 2023.Research output: Contribution to conference › Poster
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2022
How Reliable Are Gene Expression-Based and Immunohistochemical Biomarkers Assessed on a Core-Needle Biopsy? A Study of Paired Core-Needle Biopsies and Surgical Specimens in Early Breast Cancer
Saghir, H., Veerla, S., Malmberg, M., Rydén, L., Ehinger, A., Saal, L. H., Vallon-Christersson, J., Borg, Å., Hegardt, C., Larsson, C., Haidar, A., Hedenfalk, I., Loman, N. & Kimbung, S., 2022 Aug 18, In: Cancers. 14, 16, p. 1-16 4000.Research output: Contribution to journal › Article › peer-review
Open Access -
Interferon Alpha-Inducible Protein 27 Expression Is Linked to Disease Severity in Chronic Infection of Both HIV-1 and HIV-2
Palm, A. A., Veerla, S., Lindman, J., Isberg, P.-E., Johansson, E., Biague, A., Månsson, F., Norrgren, H., Esbjörnsson, J., Medstrand, P. & Jansson, M., 2022 Jun 1, In: Frontiers in Virology. 2Research output: Contribution to journal › Article › peer-review
Open Access -
SRIQ clustering: A fusion of Random Forest, QT clustering, and KNN concepts
Karlström, J., Aine, M., Staaf, J. & Veerla, S., 2022, In: Computational and Structural Biotechnology Journal. 20, p. 1567-1579 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Detection of Copy Number Aberration and Tumor Fraction in Archival Cervical Specimens from Ovarian Cancer Patients using Shallow Whole Genome Sequencing.
Martin de la Fuente, L., Li, M., Veerla, S. & Hedenfalk, I., 2021 May 11, (Accepted/In press).Research output: Contribution to conference › Poster
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Distinct mechanisms of resistance to fulvestrant treatment dictate level of ER independence and selective response to CDK inhibitors in metastatic breast cancer
Kaminska, K., Akrap, N., Staaf, J., Alves, C. L., Ehinger, A., Ebbesson, A., Hedenfalk, I., Beumers, L., Veerla, S., Harbst, K., Ehmsen, S., Borgquist, S., Borg, Å., Pérez-Fidalgo, A., Ditzel, H. J., Bosch, A. & Honeth, G., 2021 Feb 18, In: Breast cancer research : BCR. 23, 1, p. 26Research output: Contribution to journal › Article › peer-review
Open Access -
2019
A human antithrombin isoform dampens inflammatory responses and protects from organ damage during bacterial infection
Papareddy, P., Rossnagel, M., Doreen Hollwedel, F., Kilic, G., Veerla, S., Naudin, C., Smeds, E., Westman, J., Martinez-Martinez, I., Egesten, A., de la Morena-Barrio, M. E., Corral, J., Linder, A., Artoni, A., Abbattista, M., Novembrino, C., Herbert Brakebusch, C., Martinelli, I., Kasetty, G. & Herwald, H., 2019, In: Nature Microbiology. 4, 12, p. 2442-2455Research output: Contribution to journal › Article › peer-review
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2018
Promoter-associated proteins of EPAS1 identified by enChIP-MS – A putative role of HDX as a negative regulator
Hamidian, A., Vaapil, M., von Stedingk, K., Fujita, T., Persson, C. U., Eriksson, P., Veerla, S., De Preter, K., Speleman, F., Fujii, H., Påhlman, S. & Mohlin, S., 2018 May 5, In: Biochemical and Biophysical Research Communications. 499, 2, p. 291-298 8 p.Research output: Contribution to journal › Article › peer-review
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Assessment of early response biomarkers in relation to long-term survival in patients with HER2-negative breast cancer receiving neoadjuvant chemotherapy plus bevacizumab: Results from the Phase II PROMIX trial
Kimbung, S., Markholm, I., Bjöhle, J., Lekberg, T., Wachenfeldt, V. A., Azavedo, E., Saracco, A., Hellström, M., Veerla, S., Paquet, E., Bendahl, P. O., Fernö, M., Bergh, J., Loman, N., Hatschek, T. & Hedenfalk, I., 2018, In: International Journal of Cancer. 142, 3, p. 618-628Research output: Contribution to journal › Article › peer-review
Open Access -
2017
Cell-Type-Specific Gene Programs of the Normal Human Nephron Define Kidney Cancer Subtypes
Lindgren, D., Eriksson, P., Krawczyk, K., Nilsson, H., Hansson, J., Veerla, S., Sjölund, J., Höglund, M., Johansson, M. E. & Axelson, H., 2017 Aug 8, In: Cell Reports. 20, 6, p. 1476-1489 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Gene expression profiling of large cell lung cancer links transcriptional phenotypes to the new histological WHO2015 classification
Karlsson, A., Brunnström, H., Micke, P., Veerla, S., Mattsson, J. M., La Fleur, L., Botling, J., Jönsson, M., Reuterswärd, C., Planck, M. & Staaf, J., 2017, In: Journal of Thoracic Oncology. 12, 8, p. 1257-1267Research output: Contribution to journal › Article › peer-review
Open Access -
2016
CYP1A2 - a novel genetic marker for early aromatase inhibitor response in the treatment of breast cancer patients
Simonsson, M., Veerla, S., Markkula, A., Rose, C., Ingvar, C. & Jernström, H., 2016, In: BMC Cancer. 16, 1, 256.Research output: Contribution to journal › Article › peer-review
Open Access -
Transcriptional profiling of breast cancer metastases identifies liver metastasis-selective genes associated with adverse outcome in luminal A primary breast cancer.
Kimbung, S., Johansson, I., Danielsson, A., Veerla, S., Brage, S. E., Frostvik Stolt, M., Skoog, L., Carlsson, L., Einbeigi, Z., Lidbrink, E., Linderholm, B. K., Loman, N., Malmström, P., Söderberg, M., Walz, T. M., Fernö, M., Hatschek, T. & Hedenfalk, I., 2016, In: Clinical Cancer Research. 22, 1, p. 146-157Research output: Contribution to journal › Article › peer-review
File306 Downloads (Pure) -
2015
Genetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia.
Safavi, S., Olsson, L., Biloglav, A., Veerla, S., Blendberg, M., Tayebwa, J., Behrendtz, M., Castor, A., Hansson, M., Johansson, B. & Paulsson, K., 2015, In: Oncotarget. 6, 40Research output: Contribution to journal › Article › peer-review
Open Access -
Global transcriptional changes following statin treatment in breast cancer.
Bjarnadottir, O., Kimbung, S., Johansson, I., Veerla, S., Jönsson, M., Bendahl, P.-O., Grabau, D., Hedenfalk, I. & Borgquist, S., 2015, In: Clinical Cancer Research. 21, 15, p. 3402-3411Research output: Contribution to journal › Article › peer-review
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Integrative epigenomic analysis of differential DNA methylation in urothelial carcinoma.
Aine, M., Sjödahl, G., Eriksson, P., Veerla, S., Lindgren, D., Ringnér, M. & Höglund, M., 2015, In: Genome Medicine. 7, 1, 23.Research output: Contribution to journal › Article › peer-review
Open AccessFile401 Downloads (Pure) -
Molecular subtypes of urothelial carcinoma are defined by specific gene regulatory systems.
Eriksson, P., Aine, M., Veerla, S., Liedberg, F., Sjödahl, G. & Höglund, M., 2015, In: BMC Medical Genomics. 8, 1, 25.Research output: Contribution to journal › Article › peer-review
Open AccessFile395 Downloads (Pure) -
Statin-induced anti-proliferative effects via cyclin D1 and p27 in a window-of-opportunity breast cancer trial.
Feldt, M., Bjarnadottir, O., Kimbung, S., Jirström, K., Bendahl, P.-O., Veerla, S., Grabau, D., Hedenfalk, I. & Borgquist, S., 2015, In: Journal of Translational Medicine. 13, 133Research output: Contribution to journal › Article › peer-review
Open AccessFile293 Downloads (Pure) -
2014
Transcription Factor Binding Site Analysis Identifies FOXO Transcription Factors as Regulators of the Cutaneous Wound Healing Process.
Roupé, K. M., Veerla, S., Olson, J., Stone, E. L., Sørensen, O. E., Hedrick, S. M. & Nizet, V., 2014, In: PLoS ONE. 9, 2, e89274.Research output: Contribution to journal › Article › peer-review
Open AccessFile187 Downloads (Pure) -
2013
Constitutional trisomy 8 mosaicism as a model for epigenetic studies of aneuploidy.
Davidsson, J., Veerla, S. & Johansson, B., 2013, In: Epigenetics & Chromatin. 6, 1, 18.Research output: Contribution to journal › Article › peer-review
Open AccessFile149 Downloads (Pure) -
Distinct gene expression signatures in lynch syndrome and familial colorectal cancer type x.
Dominguez, M., Therkildsen, C., Veerla, S., Jönsson, M., Bernstein, I., Borg, Å. & Nilbert, M., 2013, In: PLoS ONE. 8, 8, e71755.Research output: Contribution to journal › Article › peer-review
Open AccessFile558 Downloads (Pure) -
Identification of transcriptional subgroups in EGFR-mutated and EGFR/KRAS-wild type lung adenocarcinoma reveals gene signatures associated with patient outcome.
Planck, M., Isaksson, S., Veerla, S. & Staaf, J., 2013, In: Clinical Cancer Research. 19, 18, p. 5116-5126Research output: Contribution to journal › Article › peer-review
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Prognostic Significance in Breast Cancer of a Gene Signature Capturing Stromal PDGF Signaling
Frings, O., Augsten, M., Tobin, N. P., Carlson, J., Paulsson, J., Pena, C., Olsson, E., Veerla, S., Bergh, J., Ostman, A. & Sonnhammer, E. L. L., 2013, In: American Journal of Pathology. 182, 6, p. 2037-2047Research output: Contribution to journal › Article › peer-review
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STC1 Expression By Cancer-Associated Fibroblasts Drives Metastasis of Colorectal Cancer
Pena, C., Virtudes Cespedes, M., Lindh, M. B., Kiflemariam, S., Mezheyeuski, A., Edqvist, P.-H., Hagglof, C., Birgisson, H., Bojmar, L., Jirström, K., Sandstrom, P., Olsson, E., Veerla, S., Gallardo, A., Sjoblom, T., Chang, A. C.-M., Reddel, R. R., Mangues, R., Augsten, M. & Ostman, A., 2013, In: Cancer Research. 74, 4, p. 1287-1297Research output: Contribution to journal › Article › peer-review
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2012
A Molecular Taxonomy for Urothelial Carcinoma.
Sjödahl, G., Lauss, M., Lövgren, K., Chebil, G., Gudjonsson, S., Veerla, S., Hultman Patschan, O., Aine, M., Fernö, M., Ringnér, M., Månsson, W., Liedberg, F., Lindgren, D. & Höglund, M., 2012, In: Clinical Cancer Research. 18, 12, p. 3377-3386Research output: Contribution to journal › Article › peer-review
Open AccessFile493 Downloads (Pure) -
DNA methylation analyses of urothelial carcinoma reveal distinct epigenetic subtypes and an association between gene copy number and methylation status.
Lauss, M., Aine, M., Sjödahl, G., Veerla, S., Hultman Patschan, O., Gudjonsson, S., Chebil, G., Lövgren, K., Fernö, M., Månsson, W., Liedberg, F., Ringnér, M., Lindgren, D. & Höglund, M., 2012, In: Epigenetics. 7, 8, p. 858-867Research output: Contribution to journal › Article › peer-review
Open AccessFile274 Downloads (Pure) -
Retained heterodisomy is associated with high gene expression in hyperhaploid inflammatory leiomyosarcoma.
Hansén Nord, K., Paulsson, K., Veerla, S., Wejde, J., Brosjö, O., Mandahl, N. & Mertens, F., 2012, In: Neoplasia. 14, 9, p. 807-812Research output: Contribution to journal › Article › peer-review
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2011
FUS-CREB3L2/L1-Positive Sarcomas Show a Specific Gene Expression Profile with Upregulation of CD24 and FOXL1.
Möller, E., Hornick, J. L., Magnusson, L., Veerla, S., Domanski, H. & Mertens, F., 2011, In: Clinical Cancer Research. 17, 9, p. 2646-2656Research output: Contribution to journal › Article › peer-review
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2010
Combined gene expression and genomic profiling define two intrinsic molecular subtypes of urothelial carcinoma and gene signatures for molecular grading and outcome.
Lindgren, D., Frigyesi, A., Gudjonsson, S., Sjödahl, G., Halldén, C., Chebil, G., Veerla, S., Ryden, T., Månsson, W., Liedberg, F. & Höglund, M., 2010, In: Cancer Research. 70, 9, p. 3463-3472Research output: Contribution to journal › Article › peer-review
Open Access -
Genome-wide transcription factor binding site/promoter databases for the analysis of gene sets and co-occurrence of transcription factor binding motifs.
Veerla, S., Ringnér, M. & Höglund, M., 2010, In: BMC Genomics. 11, 145.Research output: Contribution to journal › Article › peer-review
Open AccessFile377 Downloads (Pure) -
2009
MiRNA expression in urothelial carcinomas: Important roles of miR-10a, miR-222, miR-125b, miR-7 and miR-452 for tumor stage and metastasis, and frequent homozygous losses of miR-31.
Veerla, S., Lindgren, D., Kvist, A., Frigyesi, A., Staaf, J., Persson, H., Liedberg, F., Chebil, G., Gudjonsson, S., Borg, Å., Månsson, W., Rovira, C. & Höglund, M., 2009, In: International Journal of Cancer. 124, p. 2236-2242Research output: Contribution to journal › Article › peer-review
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The DNA methylome of pediatric acute lymphoblastic leukemia.
Davidsson, J., Lilljebjörn, H., Andersson, A., Veerla, S., Heldrup, J., Behrendtz, M., Fioretos, T. & Johansson, B., 2009, In: Human Molecular Genetics. Aug 13, p. 4054-4065Research output: Contribution to journal › Article › peer-review
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2008
CANCER-RELATED GENE REGULATION MECHANISMS
Veerla, S., 2008, Department of Clinical Genetics, Lund University. 104 p.Research output: Thesis › Doctoral Thesis (compilation)
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Promoter analysis of epigenetically controlled genes in bladder cancer.
Veerla, S., Panagopoulos, I., Jin, Y., Lindgren, D. & Höglund, M., 2008, In: Genes, Chromosomes and Cancer. 47, p. 368-378Research output: Contribution to journal › Article › peer-review
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The hypermethylome of pediatric acute lymphoblastic leukemia
Davidsson, J., Lilljebjörn, H., Andersson, A., Veerla, S., Heldrup, J., Behrendtz, M., Fioretos, T. & Johansson, B., 2008, In: Cellular Oncology. 30, 3, p. 252-252Research output: Contribution to journal › Published meeting abstract › peer-review
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Tiling resolution array CGH and high density expression profiling of urothelial carcinomas delineate genomic amplicons and candidate target genes specific for advanced tumors.
Heidenblad, M., Lindgren, D., Jonson, T., Liedberg, F., Veerla, S., Chebil, G., Gudjonsson, S., Borg, Å., Månsson, W. & Höglund, M., 2008, In: BMC Medical Genomics. 1, Jan 31, 3.Research output: Contribution to journal › Article › peer-review
File248 Downloads (Pure)