Research output per year
Research output per year
- 30 results
Search results
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2022
Safety, Pharmacokinetics, and Pharmacodynamics of the ADAMTS-5 Inhibitor GLPG1972/S201086 in Healthy Volunteers and Participants With Osteoarthritis of the Knee or Hip
van der Aar, E., Deckx, H., Dupont, S., Fieuw, A., Delage, S., Larsson, S., Struglics, A., Lohmander, L. S., Lalande, A., Leroux, E., Amantini, D. & Passier, P., 2022, In: Clinical Pharmacology in Drug Development. 11, 1, p. 112-122 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The alarmins high mobility group box protein 1 and S100A8/A9 display different inflammatory profiles after acute knee injury
Aulin, C., Larsson, S., Vogl, T., Roth, J., Åkesson, A., Swärd, P., Heinbäck, R., Erlandsson Harris, H. & Struglics, A., 2022, In: Osteoarthritis and Cartilage. 30, 9, p. 1198-1209 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
An Anterior Cruciate Ligament Rupture Increases Levels of Urine N-terminal Cross-linked Telopeptide of Type I Collagen, Urine C-terminal Cross-linked Telopeptide of Type II Collagen, Serum Aggrecan ARGS Neoepitope, and Serum Tumor Necrosis Factor–α
Hagemans, F. J. A., Larsson, S., Reijman, M., Frobell, R. B., Struglics, A. & Meuffels, D. E., 2021, In: American Journal of Sports Medicine. 49, 13, p. 3534-3543Research output: Contribution to journal › Article › peer-review
Open Access -
2020
Higher aggrecan 1-F21 epitope concentration in synovial fluid early after anterior cruciate ligament injury is associated with worse knee cartilage quality assessed by gadolinium enhanced magnetic resonance imaging 20 years later
Neuman, P., Larsson, S., Lohmander, L. S. & Struglics, A., 2020, In: BMC Musculoskeletal Disorders. 21, 1, 798.Research output: Contribution to journal › Article › peer-review
Open Access -
Molecular and imaging biomarkers of local inflammation at 2 years after anterior cruciate ligament injury do not associate with patient reported outcomes at 5 years
Struglics, A., Turkiewicz, A., Larsson, S., Lohmander, L. S., Roemer, F. W., Frobell, R. & Englund, M., 2020 Mar 1, In: Osteoarthritis and Cartilage. 28, 3, p. 356-362 7 p.Research output: Contribution to journal › Article › peer-review
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2019
Impact of exercise therapy on molecular biomarkers related to cartilage and inflammation in people at risk of, or with established, knee osteoarthritis: a systematic review and meta-analysis of randomized controlled trials
Bricca, A., Struglics, A., Larsson, S., Steultjens, M., Juhl, C. B. & Roos, E. M., 2019 Nov, In: Arthritis care and research : the official journal of the Arthritis Health Professions Association. 71, 11, p. 1504-1515 12 p.Research output: Contribution to journal › Article › peer-review
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Molecular and Structural Biomarkers of Inflammation at Two Years After Acute Anterior Cruciate Ligament Injury Do Not Predict Structural Knee Osteoarthritis at Five Years
Roemer, F. W., Englund, M., Turkiewicz, A., Struglics, A., Guermazi, A., Lohmander, L. S., Larsson, S. & Frobell, R., 2019, In: Arthritis and Rheumatology. 71, 2, p. 238-243Research output: Contribution to journal › Article › peer-review
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Reply to letter by Deng et al. "Could the levels of inflammation biomarkers predict OA? Comment on the article by Roemer FW et al."
Roemer, F. W., Englund, M., Turkiewicz, A., Struglics, A., Guermazi, A., Lohmander, L. S., Larsson, S. & Frobell, R., 2019, In: Arthritis & Rheumatology. 71, 9, p. 1588-1588Research output: Contribution to journal › Letter
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2018
Changes in synovial fluid and serum concentrations of cartilage oligomeric matrix protein over 5 years after anterior cruciate ligament rupture: an exploratory analysis in the KANON trial
Struglics, A., Larsson, S., Pramhed, A., Frobell, R. & Swärd, P., 2018 Jan, In: Osteoarthritis and Cartilage. 26, 10, p. 1351-1358Research output: Contribution to journal › Article › peer-review
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Dickkopf-related protein 1 and gremlin 1 show different response than frizzled-related protein in human synovial fluid following knee injury and in patients with osteoarthritis
Huang, X., Post, J. N., Zhong, L., Leijten, J., Larsson, S., Karperien, M. & Struglics, A., 2018 Jun, In: Osteoarthritis and Cartilage. 26, 6, p. 834-843Research output: Contribution to journal › Article › peer-review
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Time between anterior cruciate ligament injury and reconstruction and cartilage metabolism six-months following reconstruction
Davis, H. C., Spang, J. T., Loeser, R. F., Larsson, S., Ulici, V., Troy Blackburn, J., Creighton, R. A., Kamath, G. M., Jordan, J. M., Marshall, S. W. & Pietrosimone, B., 2018 Mar, In: Knee. 25, 2, p. 296-305Research output: Contribution to journal › Article › peer-review
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α1-microglobulin protects against bleeding-induced oxidative damage in knee arthropathies
Larsson, S., Åkerström, B., Gram, M., Stefan Lohmander, L. & Struglics, A., 2018 Nov 16, In: Frontiers in Physiology. 9, NOV, 1596.Research output: Contribution to journal › Article › peer-review
Open Access -
2017
Surgical reconstruction of ruptured anterior cruciate ligament prolongs trauma-induced increase of inflammatory cytokines in synovial fluid: An exploratory analysis in the KANON trial
Larsson, S., Struglics, A., Lohmander, L. S. & Frobell, R., 2017 Sep, In: Osteoarthritis and Cartilage. 25, 9, p. 1443-1451Research output: Contribution to journal › Article › peer-review
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2015
Changes in synovial fluid and serum cytokines and ARGS-aggrecan, and urine CTX-II and NTX-I over five years after anterior cruciate ligament rupture: An exploratory analysis in the KANON trial.
Struglics, A., Larsson, S., Kumahashi, N., Frobell, R. & Lohmander, S., 2015, In: Arthritis & Rheumatology. 67, 7, p. 1816-1825Research output: Contribution to journal › Article › peer-review
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Interleukin-6 and tumor necrosis factor alpha in synovial fluid are associated with progression of radiographic knee osteoarthritis in subjects with previous meniscectomy.
Larsson, S., Englund, M., Struglics, A. & Lohmander, S., 2015, In: Osteoarthritis and Cartilage. 23, 11, p. 1906-1914Research output: Contribution to journal › Article › peer-review
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Type II collagen C2C epitope in human synovial fluid and serum after knee injury - associations with molecular and structural markers of injury.
Kumahashi, N., Swärd, P., Larsson, S., Lohmander, S., Frobell, R. & Struglics, A., 2015, In: Osteoarthritis and Cartilage. 23, 9, p. 1506-1512Research output: Contribution to journal › Article › peer-review
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2014
An ARGS-aggrecan assay for analysis in blood and synovial fluid.
Larsson, S., Lohmander, S. & Struglics, A., 2014, In: Osteoarthritis and Cartilage. 22, 2, p. 242-249Research output: Contribution to journal › Article › peer-review
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2012
The association between changes in synovial fluid levels of ARGS-aggrecan fragments, progression of radiographic osteoarthritis and self-reported outcomes: a cohort study.
Larsson, S., Englund, M., Struglics, A. & Lohmander, S., 2012, In: Osteoarthritis and Cartilage. 20, 5, p. 388-395Research output: Contribution to journal › Article › peer-review
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2011
Elevated aggrecanase activity in a rat model of joint injury is attenuated by an aggrecanase specific inhibitor
Chockalingam, P. S., Sun, W., Rivera-Bermudez, M. A., Zeng, W., Dufield, D. R., Larsson, S., Lohmander, S., Flannery, C. R., Glasson, S. S., Georgiadis, K. E. & Morris, E. A., 2011, In: Osteoarthritis and Cartilage. 19, 3, p. 315-323Research output: Contribution to journal › Article › peer-review
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2010
A comparison of different purification methods of aggrecan fragments from human articular cartilage and synovial fluid.
Struglics, A. & Larsson, S., 2010, In: Matrix Biology. 29, p. 74-83Research output: Contribution to journal › Article › peer-review
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Aggrecan fragments as biomarkers in osteoarthritis
Larsson, S., 2010, Lund Univerity, Faculty of Medicine, Clinical Sciences Lund, Department of Orthopaedics, SE-221 84 Lund, Sweden. 130 p.Research output: Thesis › Doctoral Thesis (compilation)
File870 Downloads (Pure) -
Association between synovial fluid levels of aggrecan ARGS fragments and radiographic progression in knee osteoarthritis.
Larsson, S., Englund, M., Struglics, A. & Lohmander, S., 2010, In: Arthritis Research and Therapy. 12, 6, R230.Research output: Contribution to journal › Article › peer-review
File158 Downloads (Pure) -
The association between synovial fluid levels of aggrecan ARGS fragments and radiographic progression of knee osteoarthritis
Larsson, S., Englund, M., Struglics, A. & Lohmander, S., 2010, In: Osteoarthritis and Cartilage. 18, Supplement 2, p. S59-S60Research output: Contribution to journal › Published meeting abstract
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2009
Synovial fluid level of aggrecan ARGS fragments is a more sensitive marker of joint disease than glycosaminoglycan or aggrecan levels: a cross-sectional study
Larsson, S., Lohmander, S. & Struglics, A., 2009, In: Arthritis Research and Therapy. 11, 3Research output: Contribution to journal › Article › peer-review
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Western blot quantification of aggrecan fragments in human synovial fluid indicates differences in fragment patterns between joint diseases.
Struglics, A., Larsson, S., Björklund, M. & Lohmander, S., 2009, In: Osteoarthritis and Cartilage. 17, p. 497-506Research output: Contribution to journal › Article › peer-review
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2006
Development and characterization of a highly specific and sensitive sandwich ELISA for detection of aggrecanase-generated aggrecan fragments
Pratta, M. A., Su, J. L., Leesnitzer, M. A., Struglics, A., Larsson, S., Lohmander, S. & Kumar, S., 2006, In: Osteoarthritis and Cartilage. 14, 7, p. 702-713Research output: Contribution to journal › Article › peer-review
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Estimation of the identity of proteolytic aggrecan fragments using PAGE migration and Western immunoblot.
Struglics, A., Larsson, S. & Lohmander, S., 2006, In: Osteoarthritis and Cartilage. 14, 9, p. 898-905Research output: Contribution to journal › Article › peer-review
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Human osteoarthritis synovial fluid and joint cartilage contain both aggrecanase- and matrix metalloproteinase-generated aggrecan fragments.
Struglics, A., Larsson, S., Pratta, M. A., Kumar, S., Lark, M. W. & Lohmander, S., 2006, In: Osteoarthritis and Cartilage. 14, 2, p. 101-113Research output: Contribution to journal › Article › peer-review
File164 Downloads (Pure) -
2005
Use of the plasma stromelysin (matrix metalloproteinase 3) concentration to predict joint space narrowing in knee osteoarthritis.
Lohmander, S., Brandt, K. D., Mazzuca, S. A., Katz, B. P., Larsson, S., Struglics, A. & Lane, K. A., 2005, In: Arthritis and Rheumatism. 52, 10, p. 3160-3167Research output: Contribution to journal › Article › peer-review
Open Access -
2003
Human CD34+ hematopoietic stem cells capable of multilineage engrafting NOD/SCID mice express flt3: distinct flt3 and c-kit expression and response patterns on mouse and candidate human hematopoietic stem cells.
Sitnicka Quinn, E., Buza-Vidas, N., Larsson, S., Nygren, J., Liuba, K. & Jacobsen, S. E. W., 2003, In: Blood. 102, 3, p. 881-886Research output: Contribution to journal › Article › peer-review
Open Access