Personal profile
Research
My research focus is on preeclampsia. Based on findings from protein- and gene array studies, free fetal hemoglobin has been shown to be a potential new predictive- and diagnostic marker for preeclampsia. We are now focusing on a new potential treatment for preeclampsia based on a free hemoglobin scavenger, alpha-1-microglobulin (A1M).
Societal impact
Free fetal hemoglobin as a potential new predictive- and diagnostic marker for preeclampsia is further developed in a biotech company, Preelumina Diagnostics, that I am cofounder of. I am also cofunder of A1M Pharma, a company that is developing a new potential therapeutic drug for preeclampsia.
Subject classification (UKÄ)
- Gynaecology, Obstetrics and Reproductive Medicine
Free keywords
- Preeclampsia
- free fetal hemoglobin
- alpha-1-microglubin
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
-
SDG 3 Good Health and Well-being -
SDG 11 Sustainable Cities and Communities
Fingerprint
- 1 Similar Profiles
Collaborations the last five years
Research output
-
Inventory of Novel Animal Models Addressing Etiology of Preeclampsia in the Development of New Therapeutic/Intervention Opportunities.
Erlandsson, L., Nääv, Å., Hennessy, A., Vaiman, D., Gram, M., Åkerström, B. & Hansson, S., 2016, In: American Journal of Reproductive Immunology. 75, 3, p. 402-410Research output: Contribution to journal › Review article › peer-review
Open AccessFile343 Downloads (Pure) -
Fetal hemoglobin in preeclampsia: a new causative factor, a tool for prediction/diagnosis and a potential target for therapy.
Hansson, S., Gram, M. & Åkerström, B., 2013, In: Current Opinion in Obstetrics & Gynecology. 25, 6, p. 448-455Research output: Contribution to journal › Review article › peer-review
-
A1M Ameliorates Preeclampsia-Like Symptoms in Placenta and Kidney Induced by Cell-Free Fetal Hemoglobin in Rabbit.
Nääv, Å., Erlandsson, L., Axelsson, J., Larsson, I., Johansson, M., Wester Rosenlöf, L., Mörgelin, M., Casslén, V., Gram, M., Åkerström, B. & Hansson, S., 2015, In: PLoS ONE. 10, 5, e0125499.Research output: Contribution to journal › Article › peer-review
Open AccessFile495 Downloads (Pure) -
A1M/α1-Microglobulin Protects from Heme-Induced Placental and Renal Damage in a Pregnant Sheep Model of Preeclampsia.
Wester Rosenlöf, L., Casslén, V., Axelsson, J., Edström, A., Gram, M., Holmqvist, M., Johansson, M., Larsson, I., Ley, D., Marsal, K., Mörgelin, M., Rippe, B., Rutardottir, S., Shohani, B., Åkerström, B. & Hansson, S., 2014, In: PLoS ONE. 9, 1, e86353.Research output: Contribution to journal › Article › peer-review
Open AccessFile335 Downloads (Pure) -
Extracellular fetal hemoglobin induces increases in glomerular permeability: inhibition with alfa-1-microglobulin and tempol
Sverrisson, K., Axelsson, J., Rippe, A., Gram, M., Åkerström, B., Hansson, S. & Rippe, B., 2014, In: American Journal of Physiology-Renal Physiology. 306, 4, p. F442-F448Research output: Contribution to journal › Article › peer-review
-
Minskning och tidig diagnos av anastomosläckage efter tarmkirurgi för gynekologisk cancer
Teurneau-Hermansson, V. (Research student), Asp, M. (Assistant supervisor) & Hansson, S. (Supervisor)
2024/03/01 → 2032/03/01
Project: Dissertation
-
PE in A1Mko: Pathological findings in A1M ko/STOX-1 preeclampsia: mouse-model study
Aleksenko, L. (PI), Erlandsson, L. (Assistant supervisor) & Hansson, S. (Supervisor)
European Commission - övriga program, ej FP7
2017/02/20 → …
Project: Research
-
Gravida kvinnor och smutsig luft
Hansson, S. (Researcher) & Isaxon, C. (Researcher)
Swedish Council for Working Life and Social Research (Forte)
2017/01/01 → …
Project: Research
-
Cardiovascular risk factors during pregnancy: Mechanisms explaining utero-placental, fetal and maternal cardiovascular function in normal and complicated pregnancies
Hedström, E. (PI), Hansson, S. (PI), Ley, D. (PI), Morsing, E. (PI) & Liuba, P. (PI)
2015/02/01 → …
Project: Research
Activities
- 1 Organisation of workshop/ seminar/ course
-
SAFT "Obstetrik och anestesi"
Thomas, O. (Organiser), Persson, K. (Chair), Tranberg Lindqvist, A. (Chair), Levin, K. (Session chair), Karlsson, O. (Invited speaker), Lykke, J. (Invited speaker), Hansson, S. (Invited speaker), Hörsel, E. (Invited speaker), Thorlacius, K. (Invited speaker) & Strevens, H. (Invited speaker)
2019 Sept 8Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course