Stina Oredsson

2025

High-throughput non-homogenous 3D polycaprolactone scaffold for cancer cell and cancer-associated fibroblast mini-tumors to evaluate drug treatment response

Malakpour-Permlid, A., Rodriguez, M. M., Untracht, G. R., Andersen, P. E., Oredsson, S., Boisen, A. & Zór, K., 2025 Jun, In: Toxicology Reports. 14, 101863.

Research output: Contribution to journal › Article › peer-review

Open Access

2024

Preparation of a universally usable, animal product free, defined medium for 2D and 3D culturing of normal and cancer cells

Weber, T., Bajramovic, J. & Oredsson, S., 2024 Jun, In: MethodsX. 12, 102592.

Research output: Contribution to journal › Article › peer-review

Open Access

2023

A new animal product free defined medium for 2D and 3D culturing of normal and cancer cells to study cell proliferation and migration as well as dose response to chemical treatment

Rafnsdóttir, Ó. B., Kiuru, A., Tebäck, M., Friberg, N., Revstedt, P., Zhu, J., Thomasson, S., Czopek, A., Malakpour-Permlid, A., Weber, T. & Oredsson, S., 2023, In: Toxicology Reports. 10, p. 509-520 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2022

Case Studies Exemplifying the Transition to Animal Component-free Cell Culture

Weber, T., Wiest, J., Oredsson, S. & Bieback, K., 2022 Sept, In: Alternatives to Laboratory Animals. 50, 5, p. 330-338 9 p.

Research output: Contribution to journal › Article › peer-review

Alpha-Amylase Inhibits Cell Proliferation and Glucose Uptake in Human Neuroblastoma Cell Lines

Pierzynowska, K., Thomasson, S. & Oredsson, S., 2022, In: BioMed Research International. 2022, 4271358.

Research output: Contribution to journal › Article › peer-review

Open Access

Cytotoxic and other bioactivities of a novel and known sesquiterpene lactones isolated from Vernonia leopoldi (Sch. Bip. ex Walp.) Vatke in breast cancer cell lines

Tuasha, N., Escobar, Z., Seifu, D., Gadisa, E., Petros, B., Sterner, O. & Oredsson, S., 2022, In: Toxicology Reports. 9, p. 382-392 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2021

Breast cancer cell line toxicity of a flavonoid isolated from Baccharis densiflora

Sotillo, W. S., Tarqui, S., Huang, X., Almanza, G. & Oredsson, S., 2021 Dec 1, In: BMC Complementary Medicine and Therapies. 21, 1, 188.

Research output: Contribution to journal › Article › peer-review

Open Access

Identification of Extracellular Matrix Proteins Secreted by Human Dermal Fibroblasts Cultured in 3D Electrospun Scaffolds

Malakpour Permlid, A., Buzzi, I., Hegardt, C., Johansson, F. & Oredsson, S., 2021 Mar 23, In: Scientific Reports. 11, 18 p., 6655.

Research output: Contribution to journal › Article › peer-review

Open Access

A Novel 3D Polycaprolactone High-Throughput System for Evaluation of Toxicity in Normoxia and Hypoxia

Malakpour Permlid, A. & Oredsson, S., 2021 Mar 20, In: Toxicology Reports. 8, p. 627-635

Research output: Contribution to journal › Article › peer-review

Open Access

2020

Amylase-Dependent Regulation of Glucose Metabolism and Insulin/Glucagon Secretion in the Streptozotocin-Induced Diabetic Pig Model and in a Rat Pancreatic Beta-Cell Line, BRIN-BD11

Pierzynowska, K., Oredsson, S. & Pierzynowski, S., 2020, In: Journal of Diabetes Research. 2020, 2148740.

Research output: Contribution to journal › Article › peer-review

Open Access

Quantifying the rate, degree, and heterogeneity of morphological change during an epithelial to mesenchymal transition using digital holographic cytometry

Kamlund, S., Janicke, B., Alm, K., Judson-Torres, R. L. & Oredsson, S., 2020, In: Applied Sciences (Switzerland). 10, 14, 4726.

Research output: Contribution to journal › Article › peer-review

Open Access

Salinomycin treatment specifically inhibits cell proliferation of cancer stem cells revealed by longitudinal single cell tracking in combination with fluorescence microscopy

Kamlund, S., Janicke, B., Alm, K. & Oredsson, S., 2020, In: Applied Sciences (Switzerland). 10, 14, 4732.

Research output: Contribution to journal › Article › peer-review

Open Access

Solvent fractions of selected Ethiopian medicinal plants used in traditional breast cancer treatment inhibit cancer stem cells in a breast cancer cell line

Tuasha, N., Seifu, D., Gadisa, E., Petros, B. & Oredsson, S., 2020, In: BMC Complementary Medicine and Therapies. 20, 1, 366.

Research output: Contribution to journal › Article › peer-review

Open Access

2019

Cytotoxicity of New Damsin Derivatives in Breast Cancer Cells

Lozano , M., Soria , W., Almanza, G. (Contributor), Manner, S., Oredsson, S., Villagomez, J. R. V. & Sterner, O., 2019 Aug 27, In: Journal of Pharmacy & Drug Development. 1, 2, 19 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Unique animal friendly 3D culturing of human cancer and normal cells

Malakpour Permlid, A., Roci, P., Fredlund, E., Fält, F., Önell, E., Johansson, P. F. & Oredsson, S., 2019 May 10, In: Toxicology in Vitro. 60, p. 51-60

Research output: Contribution to journal › Article › peer-review

Open Access

Selective Cytotoxicity of Damsin Derivatives in Breast Cancer Cells

Lozano , M., Soria , W., Almanza, G., Manner, S., Oredsson, S., Villagomez, J. R. V. & Sterner, O., 2019 Apr 19, In: Journal of Advanced Pharmaceutical Science and Technology. 2, 1, p. 23-37

Research output: Contribution to journal › Article › peer-review

Open Access

Extracellular and intracellular small-molecule galectin-3 inhibitors

Stegmayr, J., Zetterberg, F., Carlsson, M. C., Huang, X., Sharma, G., Kahl-Knutson, B., Schambye, H., Nilsson, U. J., Oredsson, S. & Leffler, H., 2019 Feb 18, In: Scientific Reports. 9, 1, 2186.

Research output: Contribution to journal › Article › peer-review

Open Access

2018

Quinoline-galactose hybrids bind selectively with high affinity to a galectin-8 N-terminal domain

Pal, K. B., Mahanti, M., Huang, X., Persson, S., Sundin, A. P., Zetterberg, F. R., Oredsson, S., Leffler, H. & Nilsson, U. J., 2018 Aug 3, In: Organic and Biomolecular Chemistry. 16, 34, p. 6295-6305 11 p.

Research output: Contribution to journal › Article › peer-review

Open Access

The Molecular Basis for Inhibition of Stemlike Cancer Cells by Salinomycin

Huang, X., Borgström, B., Stegmayr, J., Abassi, Y., Kruszyk, M., Leffler, H., Persson, L., Albinsson, S., Massoumi, R., Scheblykin, I. G., Hegardt, C., Oredsson, S. & Strand, D., 2018 Jun 27, In: ACS Central Science. 4, 6, p. 760-767 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Semi-synthetic salinomycin analogs exert cytotoxic activity against human colorectal cancer stem cells

Klose, J., Kattner, S., Borgström, B., Volz, C., Schmidt, T., Schneider, M., Oredsson, S., Strand, D. & Ulrich, A., 2018 Jan, In: Biochemical and Biophysical Research Communications. 495, 1, p. 53-59

Research output: Contribution to journal › Article › peer-review

Aromatic heterocycle galectin-1 interactions for selective single-digit nM affinity ligands

Peterson, K., Collins, P. M., Huang, X., Kahl-Knutsson, B., Essén, S., Zetterberg, F. R., Oredsson, S., Leffler, H., Blanchard, H. & Nilsson, U. J., 2018, In: RSC Advances. 8, 44, p. 24913-24922 10 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Morphology of living cells cultured on nanowire arrays with varying nanowire densities and diameters

Li, Z., Persson, H., Adolfsson, K., Oredsson, S. & Prinz, C. N., 2018, In: Science China Life Sciences. 61, 4, p. 427-435

Research output: Contribution to journal › Article › peer-review

Single cell analysis of proliferation and movement of cancer and normal-like cells on nanowire array substrates

Li, Z., Kamlund, S., Ryser, T., Lard, M., Oredsson, S. & Prinz, C. N., 2018, In: Journal of Materials Chemistry B. 6, 43, p. 7042-7049 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2017

Cellular traction forces: a useful parameter in cancer research

Li, Z., Persson, H., Adolfsson, K., Abariute, L., Borgström, M. T., Hessman, D., Åström, K., Oredsson, S. & Prinz, C. N., 2017 Dec 14, In: Nanoscale. 9, 48, p. 19039-19044 6 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Influence of salinomycin treatment on division and movement of individual cancer cells cultured in normoxia or hypoxia evaluated with time-lapse digital holographic microscopy

Kamlund, S., Strand, D., Janicke, B., Alm, K. & Oredsson, S., 2017 Nov 2, In: Cell Cycle. 16, 21, p. 2128-2138

Research output: Contribution to journal › Article › peer-review

Structure–Activity Relationships in Salinomycin: Cytotoxicity and Phenotype Selectivity of Semi-synthetic Derivatives

Borgström, B., Huang, X., Hegardt, C., Oredsson, S. & Strand, D., 2017 Feb 10, In: Chemistry - A European Journal. 23, 9, p. 2077-2083 7 p.

Research output: Contribution to journal › Article › peer-review

Anti-cancer stem cell activity of a sesquiterpene lactone isolated from Ambrosia arborescens and of a synthetic derivative

Sotillo, W. S., Villagomez, R., Smiljanic, S., Huang, X., Malakpour, A., Kempengren, S., Rodrigo, G., Almanza, G., Sterner, O. & Oredsson, S., 2017, In: PLoS ONE. 12, 9, p. e0184304

Research output: Contribution to journal › Article › peer-review

Open Access

Bivalent polyether ionophores: Synthesis and biological evaluation of C₂-symmetric salinomycin dimers

Antoszczak, M., Maj, E., Borgström, B., Oredsson, S., Huczyński, A., Wietrzyk, J. & Strand, D., 2017, In: Tetrahedron Letters. 58, 24, p. 2396-2399 4 p.

Research output: Contribution to journal › Article › peer-review

2016

Determination of free and esterified carotenoid composition in rose hip fruit by HPLC-DAD-APCI⁺-MS

Zhong, L., Gustavsson, K. E., Oredsson, S., Głąb, B., Yilmaz, J. L. & Olsson, M. E., 2016 Nov 1, In: Food Chemistry. 210, p. 541-550 10 p.

Research output: Contribution to journal › Article › peer-review

Development of stable haploid strains and molecular genetic tools for Naumovozyma castellii (Saccharomyces castellii)

Karademir Andersson, A., Oredsson, S. & Cohn, M., 2016 Sept 26, In: Yeast. 33, 12, p. 633–646 14 p.

Research output: Contribution to journal › Article › peer-review

Acrylamide affects proliferation and differentiation of the neural progenitor cell line C17.2 and the neuroblastoma cell line SH-SY5Y

Attoff, K., Kertika, D., Lundqvist, J., Oredsson, S. & Forsby, A., 2016 Sept 1, In: Toxicology in Vitro. 35, p. 100-111 12 p.

Research output: Contribution to journal › Article › peer-review

Open Access

Salinomycin Hydroxamic Acids: Synthesis, Structure, and Biological Activity of Polyether Ionophore Hybrids

Borgström, B., Huang, X., Chygorin, E., Oredsson, S. & Strand, D., 2016 Apr 25, In: ACS Medicinal Chemistry Letters. 7, 6, p. 635-640 6 p.

Research output: Contribution to journal › Article › peer-review

Apparent exchange rate for breast cancer characterization.

Lasič, S., Oredsson, S., Partridge, S. C., Saal, L., Topgaard, D., Nilsson, M. & Bryskhe, K., 2016, In: NMR in Biomedicine. 29, 5, p. 631–639

Research output: Contribution to journal › Article › peer-review

Open Access

Breast cancer stem cell selectivity of synthetic nanomolar-active salinomycin analogs.

Huang, X., Borgström, B., Kempengren, S., Persson, L., Hegardt, C., Strand, D. & Oredsson, S., 2016, In: BMC Cancer. 16, 1, 145.

Research output: Contribution to journal › Article › peer-review

Open Access

Galectin-3-Binding Glycomimetics that Strongly Reduce Bleomycin-Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition

Delaine, T., Collins, P., Mackinnon, A., Sharma, G., Stegmayr, J., Rajput, V. K., Mandal, S., Cumpstey, I., Larumbe, A., Salameh, B. A., Kahl Knutson, B., vanHattum, H., van Scherpenzeel, M., Pieters, R. J., Sethi, T., Schambye, H., Oredsson, S., Leffler, H., Blanchard, H. & Nilsson, U., 2016, In: ChemBioChem. 17, 18, p. 1759-1770

Research output: Contribution to journal › Article › peer-review

Open Access

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Low or No Inhibitory Potency of the Canonical Galectin Carbohydrate-binding Site by Pectins and Galactomannans

Stegmayr, J., Lepur, A., Kahl Knutson, B., Aguilar-Moncayo, M., Klyosov, A. A., Field, R. A., Oredsson, S., Nilsson, U. & Leffler, H., 2016, In: Journal of Biological Chemistry. 291, 25, p. 13318-13334 17 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2015

A role for antizyme inhibitor in cell proliferation.

Silva, T., Cirenajwis, H., Wallace, H. M., Oredsson, S. & Persson, L., 2015, In: Amino Acids. 47, 7, p. 1341-1352

Research output: Contribution to journal › Article › peer-review

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From immobilized cells to motile cells on a bed-of-nails: effects of vertical nanowire array density on cell behaviour.

Persson, H., Li, Z., Tegenfeldt, J. O., Oredsson, S. & Prinz, C., 2015, In: Scientific Reports. 5, 18535.

Research output: Contribution to journal › Article › peer-review

Open Access

2014

A novel cytotoxic terpenoid from the flowers of Kaunia lasiophthalma Griseb

Maldonado, E., Svensson, D., Oredsson, S. & Sterner, O., 2014, In: Phytochemistry Letters. 8, p. 105-108

Research output: Contribution to journal › Article › peer-review

Cytotoxic Sesquiterpene Lactones from Kauna lasiophthalma Griseb.

Maldonado, E., Svensson, D., Oredsson, S. & Sterner, O., 2014, In: Scientia Pharmaceutica. 82, 1, p. 147-160

Research output: Contribution to journal › Article › peer-review

Open Access

Increased breast cancer cell toxicity by palladination of the polyamine analogue N-1,N-11-bis(ethyl)norspermine

Silva, T. M., Fiuza, S. M., Marques, M. P. M., Persson, L. & Oredsson, S., 2014, In: Amino Acids. 46, 2, p. 339-352

Research output: Contribution to journal › Article › peer-review

Open Access

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Semisynthesis of SY-1 for Investigation of Breast Cancer Stem Cell Selectivity of C-Ring-Modified Salinomycin Analogues.

Huang, X., Borgström, B., Månsson, L., Persson, L., Oredsson, S., Hegardt, C. & Strand, D., 2014, In: ACS Chemical Biology. 9, 7, p. 1587-1594

Research output: Contribution to journal › Article › peer-review

Open Access

2013

Fibroblasts Cultured on Nanowires Exhibit Low Motility, Impaired Cell Division, and DNA Damage.

Persson, H., Købler, C., Mølhave, K., Samuelson, L., Tegenfeldt, J., Oredsson, S. & Prinz, C., 2013, In: Small. 9, 23, p. 4006-4016

Research output: Contribution to journal › Article › peer-review

Fluorescent Nanowire Heterostructures as a Versatile Tool for Biology Applications

Adolfsson, K., Persson, H., Wallentin, J., Oredsson, S., Samuelson, L., Tegenfeldt, J., Borgström, M. & Prinz, C., 2013, In: Nano Letters. 13, 10, p. 4728-4732

Research output: Contribution to journal › Article › peer-review

Norspermidine and Novel Pd(II) and Pt(II) Polynuclear Complexes of Norspermidine as Potential Antineoplastic Agents Against Breast Cancer.

Silva, T. M., Andersson, S., Sukumaran, S. K., Marques, M. P., Persson, L. & Oredsson, S., 2013, In: PLoS ONE. 8, 2, e55651.

Research output: Contribution to journal › Article › peer-review

Open Access

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Spiro-bicyclo[2.2.2]octane derivatives as paclitaxel mimetics. Synthesis and toxicity evaluation in breast cancer cell lines.

Manner, S., Oltner, V., Oredsson, S., Ellervik, U. & Frejd, T., 2013, In: Organic and Biomolecular Chemistry. 11, 41, p. 7134-7144

Research output: Contribution to journal › Article › peer-review

Synthetic modification of salinomycin: selective O-acylation and biological evaluation

Borgström, B., Huang, X., Posta, M., Hegardt, C., Oredsson, S. & Strand, D., 2013, In: Chemical Communications. 49, 85, p. 9944-9946 3 p.

Research output: Contribution to journal › Article › peer-review

Open Access

2012

Increased toxicity of a trinuclear Pt-compound in a human squamous carcinoma cell line by polyamine depletion

Kjellström, J., Oredsson, S. & Wennerberg, J., 2012, In: Cancer Cell International. 12

Research output: Contribution to journal › Article › peer-review

Open Access

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Novel anti-apoptotic effect of the retinoblastoma protein: implications for polyamine analogue toxicity.

Johansson, V., Thuvesson, I., Alm, K. & Oredsson, S., 2012, In: Amino Acids. 42, p. 929-937

Research output: Contribution to journal › Article › peer-review

Novel Pt(II) and Pd(II) complexes with polyamine analogues: Synthesis and vibrational analysis.

Silva, T., Oredsson, S., Persson, L., Woster, P. & Marques, M. P. M., 2012, In: Journal of Inorganic Biochemistry. 108, March, p. 1-7

Research output: Contribution to journal › Article › peer-review

Stina Oredsson

Research output

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