Tadeusz Wieloch

Search results

• 2022

  Homotopic contralesional excitation suppresses spontaneous circuit repair and global network reconnections following ischemic stroke

  Bice, A. R., Xiao, Q., Kong, J., Yan, P., Rosenthal, Z. P., Kraft, A. W., Smith, K., Wieloch, T., Lee, J. M., Culver, J. P. & Bauer, A. Q., 2022 Jun, In: eLife. 11, e68852.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Plastic Property 100%
  • Asymmetry 91%
  • Biological Marker 77%
  • Stroke 58%
  • Optogenetics 56%
• 2021

  Effect of Anti-inflammatory Treatment with AMD3100 and CX₃CR1 Deficiency on GABA_A Receptor Subunit and Expression of Glutamate Decarboxylase Isoforms After Stroke

  Michalettos, G., Walter, H. L., Antunes, A. R. P., Wieloch, T., Talhada, D. & Ruscher, K., 2021, In: Molecular Neurobiology. 58, 11, p. 5876-5889

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • plerixafor octahydrochloride 100%
  • CC Chemokines 87%
  • Glutamate Decarboxylase 84%
  • Chemokine Receptors 77%
  • GABA-A Receptors 73%

• Plasticity-enhancing effects of levodopa treatment after stroke

  Talhada, D., Marklund, N., Wieloch, T., Kuric, E. & Ruscher, K., 2021 Oct 1, In: International Journal of Molecular Sciences. 22, 19, 10226.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Rats 100%
  • strokes 94%
  • Levodopa 94%
  • rats 85%
  • Plasticity 78%
• 2020

  Enhanced functional recovery by levodopa is associated with decreased levels of synaptogyrin following stroke in aged mice

  Häggman Henrikson, J., Pombo Antunes, A. R., Wieloch, T. & Ruscher, K., 2020, In: Brain Research Bulletin. 155, p. 61-66 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Synaptogyrins 100%
  • Levodopa 55%
  • Stroke 34%
  • Parvalbumins 32%
  • Dopamine Receptors 28%
• 2018

  Changes in resting-state functional connectivity after stroke in a mouse brain lacking extracellular matrix components

  Quattromani, M. J., Hakon, J., Rauch, U., Bauer, A. Q. & Wieloch, T., 2018 Apr 1, In: Neurobiology of Disease. 112, p. 91-105 15 p.

  Research output: Contribution to journal › Article › peer-review

  • Extracellular Matrix 100%
  • Stroke 80%
  • Brain 58%
  • Neuronal Plasticity 37%
  • Sensorimotor Cortex 32%

• Extracellular Matrix Modulation Is Driven by Experience-Dependent Plasticity During Stroke Recovery

  Quattromani, M. J., Pruvost, M., Guerreiro, C., Backlund, F., Englund, E., Aspberg, A., Jaworski, T., Christensen, J. H., Ruscher, K., Kaczmarek, L., Vivien, D. & Wieloch, T., 2018, In: Molecular Neurobiology. 55, 3, p. 2196-2213

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Extracellular Matrix 100%
  • Stroke 80%
  • Protease Inhibitors 52%
  • Parvalbumins 43%
  • Peptide Hydrolases 42%

• Multisensory stimulation improves functional recovery and resting-state functional connectivity in the mouse brain after stroke

  Hakon, J., Quattromani, M. J., Sjölund, C., Tomasevic, G., Carey, L., Lee, J-M., Ruscher, K., Wieloch, T. & Bauer, A. Q., 2018, In: NeuroImage: Clinical. 17, p. 717-730

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Stroke 100%
  • Brain 71%
  • Parvalbumins 53%
  • Neuronal Plasticity 39%
  • Recovery of Function 33%

• Neuroprotective dobutamine treatment upregulates superoxide dismutase 3, anti-oxidant and survival genes and attenuates genes mediating inflammation

  Markus, T., Ley, D., Hansson, S. R., Wieloch, T. & Ruscher, K., 2018 Mar 9, In: BMC Neuroscience. 19, 1, 9.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dobutamine 100%
  • Superoxide Dismutase 75%
  • Antioxidants 60%
  • Up-Regulation 59%
  • Inflammation 48%
• 2017

  CX₃C chemokine receptor 1 deficiency modulates microglia morphology but does not affect lesion size and short-term deficits after experimental stroke

  van der Maten, G., Henck, V., Wieloch, T. & Ruscher, K., 2017 Jan 6, In: BMC Neuroscience. 18, 1, 11.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • CX3C Chemokine Receptor 1 100%
  • Microglia 60%
  • Stroke 40%
  • Infarction 20%
  • Leukocyte Chemotaxis 9%

• Enhancing the alignment of the preclinical and clinical stroke recovery research pipeline: Consensus-based core recommendations from the Stroke Recovery and Rehabilitation Roundtable translational working group

  Corbett, D., Carmichael, S. T., Murphy, T. H., Jones, T. A., Schwab, M. E., Jolkkonen, J., Clarkson, A. N., Dancause, N., Wieloch, T., Johansen-Berg, H., Nilsson, M., McCullough, L. D. & Joy, M. T., 2017 Jul 1, In: International Journal of Stroke. 12, 5, p. 462-471 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Stroke Rehabilitation 100%
  • Stroke 53%
  • Clinical Studies 13%
  • Clinical Trials 12%
  • Guidelines 12%

• Enhancing the Alignment of the Preclinical and Clinical Stroke Recovery Research Pipeline: Consensus-Based Core Recommendations from the Stroke Recovery and Rehabilitation Roundtable Translational Working Group ∗

  Corbett, D., Carmichael, S. T., Murphy, T. H., Jones, T. A., Schwab, M. E., Jolkkonen, J., Clarkson, A. N., Dancause, N., Wieloch, T., Johansen-Berg, H., Nilsson, M., McCullough, L. D. & Joy, M. T., 2017 Aug 1, In: Neurorehabilitation and Neural Repair. 31, 8, p. 699-707 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Stroke Rehabilitation 100%
  • Stroke 53%
  • Clinical Studies 13%
  • Clinical Trials 12%
  • Guidelines 12%

• GISCOME – Genetics of Ischaemic Stroke Functional Outcome network: A protocol for an international multicentre genetic association study

  Maguire, J. M., Bevan, S., Stanne, T. M., Lorenzen, E., Fernandez-Cadenas, I., Hankey, G. J., Jimenez-Conde, J., Jood, K., Lee, J. M., Lemmens, R., Levi, C., Norrving, B., Rannikmae, K., Rost, N., Rosand, J., Rothwell, P. M., Scott, R., Strbian, D., Sturm, J., Sudlow, C., & 8 othersTraylor, M., Thijs, V., Tatlisumak, T., Wieloch, T., Woo, D., Worrall, B. B., Jern, C. & Lindgren, A., 2017 Sep 1, In: European Stroke Journal. 2, 3, p. 229-237 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Genetic Association Studies 100%
  • Stroke 64%
  • Genetic Loci 12%
  • Genome-Wide Association Study 10%
  • Health Care Outcome Assessment 6%
• 2016

  Gephyrin Cleavage in In Vitro Brain Ischemia Decreases GABA_A Receptor Clustering and Contributes to Neuronal Death

  Costa, J. T., Mele, M., Baptista, M. S., Gomes, J. R., Ruscher, K., Nobre, R. J., de Almeida, L. P., Wieloch, T. & Duarte, C. B., 2016 Aug 1, In: Molecular Neurobiology. 53, 6, p. 3513-3527 15 p.

  Research output: Contribution to journal › Article › peer-review

  • gephyrin 100%
  • GABA-A Receptors 65%
  • Brain Ischemia 60%
  • Cluster Analysis 55%
  • In Vitro Techniques 26%
• 2015

  Treatment with AMD3100 attenuates the microglial response and improves outcome after experimental stroke.

  Walter, H. L., van der Maten, G., Antunes, A., Wieloch, T. & Ruscher, K., 2015, In: Journal of Neuroinflammation. 12, 24, p. 1-15

  Research output: Contribution to journal › Article › peer-review

  File

  • CX3C Chemokine Receptor 1 100%
  • plerixafor octahydrochloride 87%
  • Chemokine CX3CL1 50%
  • Stroke 40%
  • Microglia 34%
  144 Downloads (Pure)
• 2014

  Can diffusion kurtosis imaging improve the sensitivity and specificity of detecting microstructural alterations in brain tissue chronically after experimental stroke? Comparisons with diffusion tensor imaging and histology.

  Rudrapatna, S. U., Wieloch, T., Beirup, K., Ruscher, K., Mol, W., Yanev, P., Leemans, A., van der Toorn, A. & Dijkhuizen, R. M., 2014, In: NeuroImage. 97, Apr 15, p. 363-373

  Research output: Contribution to journal › Article › peer-review

  • Diffusion Tensor Imaging 100%
  • Histology 69%
  • Sensitivity and Specificity 65%
  • Stroke 60%
  • Brain 43%

• Enriched housing down-regulates the Toll-like receptor 2 response in the mouse brain after experimental stroke.

  Quattromani, M., Cordeau, P., Ruscher, K., Kriz, J. & Wieloch, T., 2014, In: Neurobiology of Disease. 66, Mar 6, p. 66-73

  Research output: Contribution to journal › Article › peer-review

  • Toll-Like Receptor 2 100%
  • Down-Regulation 55%
  • Stroke 53%
  • Brain 38%
  • Infarction 33%

• Enriched housing enhances recovery of limb placement ability and reduces aggrecan-containing perineuronal nets in the rat somatosensory cortex after experimental stroke.

  Madinier, A., Quattromani, M., Sjölund, C., Ruscher, K. & Wieloch, T., 2014, In: PLoS ONE. 9, 3, e93121.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Aggrecans 100%
  • Somatosensory Cortex 89%
  • Extremities 57%
  • Stroke 53%
  • Interneurons 23%
  485 Downloads (Pure)

• GABAA receptor dephosphorylation followed by internalization is coupled to neuronal death in in vitro ischemia.

  Mele, M., Ribeiro, L., Inacio, A., Wieloch, T. & Duarte, C. B., 2014, In: Neurobiology of Disease.

  Research output: Contribution to journal › Article › peer-review

  • GABA-A Receptors 100%
  • Ischemia 70%
  • Brain Ischemia 46%
  • In Vitro Techniques 40%
  • Synaptic Transmission 21%

• Impact of estrogen receptor beta activation on functional recovery after experimental stroke.

  Madinier, A., Wieloch, T., Olsson, R. & Ruscher, K., 2014, In: Behavioural Brain Research. 261, p. 282-288

  Research output: Contribution to journal › Article › peer-review

  • 4-(1-phenylcyclohexyl)phenol 100%
  • Estrogen Receptor beta 69%
  • Stroke 37%
  • Phenol 16%
  • Behavior Rating Scale 15%

• Pharmacological stimulation of sigma-1 receptors has neurorestorative effects in experimental parkinsonism.

  Francardo, V., Bez, F., Wieloch, T., Nissbrandt, H., Ruscher, K. & Cenci Nilsson, A., 2014, In: Brain. 137, Apr 22, p. 1998-2014

  Research output: Contribution to journal › Article › peer-review

  • sigma-1 receptor 100%
  • 2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate 97%
  • Parkinsonian Disorders 69%
  • Pharmacology 42%
  • Oxidopamine 29%

• Variations in apolipoprotein D and sigma non-opioid intracellular receptor 1 genes with relation to risk, severity and outcome of ischemic stroke

  Lövkvist, H., Jönsson, A-C., Luthman, H., Jood, K., Jern, C., Wieloch, T. & Lindgren, A., 2014, In: BMC Neurology. 14, 191.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Apolipoproteins D 100%
  • Stroke 40%
  • Genes 23%
  • Single Nucleotide Polymorphism 21%
  • sigma-1 receptor 20%
  158 Downloads (Pure)
• 2013

  A functional role of the cyclin-dependent kinase inhibitor 1 (p21(WAF1/CIP1)) for neuronal preconditioning

  Mergenthaler, P., Muselmann, C., Suenwoldt, J., Isaev, N. K., Wieloch, T., Dirnagl, U., Meisel, A. & Ruscher, K., 2013, In: Journal of Cerebral Blood Flow and Metabolism. 33, 3, p. 351-355

  Research output: Contribution to journal › Article › peer-review

  • CDC2 Protein Kinase 100%
  • Cyclin-Dependent Kinase Inhibitor p21 99%
  • Hypoxia-Inducible Factor 1 87%
  • Deferoxamine 43%
  • Neurons 42%

• Dopamine receptor activation increases glial cell line-derived neurotrophic factor in experimental stroke.

  Kuric, E., Wieloch, T. & Ruscher, K., 2013, In: Experimental Neurology. 247, May,9, p. 202-208

  Research output: Contribution to journal › Article › peer-review

  • Glial Cell Line-Derived Neurotrophic Factor 100%
  • Dopamine Receptors 85%
  • Stroke 51%
  • Dopamine 28%
  • levodopa drug combination benserazide 28%

• Fission and Fusion of the Neuronal Endoplasmic Reticulum

  Kucharz, K., Wieloch, T. & Toresson, H., 2013, In: Translational Stroke Research. 4, 6, p. 652-662

  Research output: Contribution to journal › Article › peer-review

  • Endoplasmic Reticulum 100%
  • N-Methyl-D-Aspartate Receptors 20%
  • Neurosciences 11%
  • In Vitro Techniques 9%
  • Microscopy 8%

• Inhibition of CXCL12 signaling attenuates the postischemic immune response and improves functional recovery after stroke.

  Ruscher, K., Kuric, E., Liu, Y., Walter, H. L., Issazadeh, S., Englund, E. & Wieloch, T., 2013, In: Journal of Cerebral Blood Flow and Metabolism. 33, 8, p. 1225-1234

  Research output: Contribution to journal › Article › peer-review

  • Stroke 100%
  • plerixafor octahydrochloride 60%
  • Infarction 34%
  • Nervous System 34%
  • Chemokine CXCL12 26%

• Post-ischemic continuous infusion of erythropoeitin enhances recovery of lost memory function after global cerebral ischemia in the rat.

  Undén, J., Sjölund, C., Länsberg, J-K., Wieloch, T., Ruscher, K. & Romner, B., 2013, In: BMC Neuroscience. 14, Mars,12, 27.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Erythropoietin 100%
  • Brain Ischemia 94%
  • Memory 69%
  • Intravenous Infusions 46%
  • Brain Diseases 45%
  135 Downloads (Pure)
• 2012

  Delayed neuromotor recovery and increased memory acquisition dysfunction following experimental brain trauma in mice lacking the DNA repair gene XPA.

  Tomasevic, G., Laurer, H. L., Mattiasson, G., Steeg, H., Wieloch, T. & McIntosh, T. K., 2012, In: Journal of Neurosurgery. 116, 6, p. 1368-1378

  Research output: Contribution to journal › Article › peer-review

  • Xeroderma Pigmentosum 100%
  • Traumatic Brain Injury 73%
  • DNA Repair 68%
  • Memory 54%
  • Genes 29%

• Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke.

  Ruscher, K., Inacio, A., Valind, K., Rowshan Ravan, A., Kuric, E. & Wieloch, T., 2012, In: PLoS ONE. 7, 9, e45118.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • SA 4503 100%
  • sigma-1 receptor 83%
  • Piperazine 75%
  • Chlorides 56%
  • Infarction 44%
  150 Downloads (Pure)

• Excitotoxicity Downregulates TrkB.FL Signaling and Upregulates the Neuroprotective Truncated TrkB Receptors in Cultured Hippocampal and Striatal Neurons.

  Rodrigues Gomes, J. C., Costa, J. T., Melo, C. V., Felizzi, F., Monteiro, P., Pinto, M. J., Inacio, A., Wieloch, T., Almeida, R. D., Grãos, M. & Duarte, C. B., 2012, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 32, 13, p. 4610-4622

  Research output: Contribution to journal › Article › peer-review

  • trkB Receptor 100%
  • Brain-Derived Neurotrophic Factor 75%
  • Corpus Striatum 69%
  • Up-Regulation 51%
  • Down-Regulation 50%

• Levodopa Treatment Improves Functional Recovery After Experimental Stroke.

  Ruscher, K., Kuric, E. & Wieloch, T., 2012, In: Stroke: a journal of cerebral circulation. 43, p. 507-513

  Research output: Contribution to journal › Article › peer-review

  • levodopa drug combination benserazide 100%
  • Levodopa 88%
  • Middle Cerebral Artery Infarction 87%
  • Astrocytes 73%
  • Dopamine Receptors 67%
• 2011

  Cleavage of the Vesicular GABA Transporter under Excitotoxic Conditions Is Followed by Accumulation of the Truncated Transporter in Nonsynaptic Sites.

  Rodrigues Gomes, J. C., Lobo, A. C., Melo, C. V., Inacio, A., Takano, J., Iwata, N., Saido, T. C., de Almeida, L. P., Wieloch, T. & Duarte, C. B., 2011, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 31, 12, p. 4622-4635

  Research output: Contribution to journal › Article › peer-review

  File

  • vesicular GABA transporter 100%
  • Calpain 27%
  • Synaptic Vesicles 17%
  • gamma-Aminobutyric Acid 14%
  • Synaptic Transmission 13%
  165 Downloads (Pure)

• Cleavage of the vesicular glutamate transporters under excitotoxic conditions

  Lobo, A. C., Gomes, J. R., Catarino, T., Mele, M., Fernandez, P., Inacio, A., Bahr, B. A., Santos, A. E., Wieloch, T., Carvalho, A. L. & Duarte, C. B., 2011, In: Neurobiology of Disease. 44, 3, p. 292-303

  Research output: Contribution to journal › Article › peer-review

  • Vesicular Glutamate Transport Proteins 100%
  • Calpain 77%
  • Synaptic Vesicles 36%
  • Down-Regulation 33%
  • Glutamic Acid 27%

• Effect of 3,4-Methylenedioxyamphetamine on Dendritic Spines Dynamics in Rat Neocortical Neurons - Involvement of Heat Shock Protein 27.

  Ruscher, K., Fernandes, E., Capela, J. P., Bastos, M. D. L., Wieloch, T., Dirnagl, U., Meisel, A. & Carvalho, F., 2011, In: Brain Research. 1370, p. 43-52

  Research output: Contribution to journal › Article › peer-review

  • 3,4-Methylenedioxyamphetamine 100%
  • HSP27 Heat-Shock Proteins 79%
  • Dendritic Spines 67%
  • Small Heat-Shock Proteins 40%
  • Neurons 34%

• Enriched environment downregulates macrophage migration inhibitory factor and increases parvalbumin in the brain following experimental stroke

  Inacio, A., Ruscher, K. & Wieloch, T., 2011, In: Neurobiology of Disease. 41, 2, p. 270-278

  Research output: Contribution to journal › Article › peer-review

  • Macrophage Migration-Inhibitory Factors 100%
  • Parvalbumins 93%
  • Middle Cerebral Artery Infarction 80%
  • Interneurons 51%
  • Down-Regulation 51%

• Potassium-induced structural changes of the endoplasmic reticulum in pyramidal neurons in murine organotypic hippocampal slices.

  Kucharz, K., Wieloch, T. & Toresson, H., 2011, In: Journal of Neuroscience Research. 89, 8, p. 1150-1159

  Research output: Contribution to journal › Article › peer-review

  • Pyramidal Cells 100%
  • Endoplasmic Reticulum 91%
  • Potassium 85%
  • N-Methyl-D-Aspartate Receptors 12%
  • Potassium-50 11%

• Rapid fragmentation of the endoplasmic reticulum in cortical neurons of the mouse brain in situ following cardiac arrest.

  Kucharz, K., Wieloch, T. & Toresson, H., 2011, In: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 31, p. 1663-1667

  Research output: Contribution to journal › Article › peer-review

  File

  • Heart Arrest 100%
  • Endoplasmic Reticulum 95%
  • Neurons 61%
  • Brain 49%
  • Induced Heart Arrest 42%
  130 Downloads (Pure)

• The sigma-1 receptor enhances brain plasticity and functional recovery after experimental stroke.

  Ruscher, K., Shamloo, M., Rickhag, M., Ladunga, I., Soriano, L., Gisselsson, L., Toresson, H., Ruslim-Litrus, L., Oksenberg, D., Urfer, R., Johansson, B., Nikolich, K. & Wieloch, T., 2011, In: Brain. 134, 3, p. 732-746

  Research output: Contribution to journal › Article › peer-review

  • sigma-1 receptor 100%
  • Neuronal Plasticity 60%
  • Stroke 43%
  • Infarction 16%
  • Middle Cerebral Artery Infarction 14%
• 2010

  beta-Adrenoceptor activation depresses brain inflammation and is neuroprotective in lipopolysaccharide-induced sensitization to oxygen-glucose deprivation in organotypic hippocampal slices

  Markus, T., Hansson, S., Cronberg, T., Cilio, C., Wieloch, T. & Ley, D., 2010, In: Journal of Neuroinflammation. 7

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Encephalitis 100%
  • Adrenergic Receptors 89%
  • Lipopolysaccharides 80%
  • Oxygen 66%
  • Glucose 59%
  291 Downloads (Pure)

• Deletion of the p53 tumor suppressor gene improves neuromotor function but does not attenuate regional neuronal cell loss following experimental brain trauma in mice.

  Tomasevic, G., Raghupathi, R., Scherbel, U., Wieloch, T. & McIntosh, T. K., 2010, In: Journal of Neuroscience Research. 88, 15, p. 3414-3423

  Research output: Contribution to journal › Article › peer-review

  • Tumor Suppressor Genes 100%
  • Traumatic Brain Injury 99%
  • p53 Genes 55%
  • Brain 37%
  • Rotarod Performance Test 36%

• Effects of chronic clozapine administration on apolipoprotein D levels and on functional recovery following experimental stroke.

  Ruscher, K., Erickson, A., Kuric, E., Inacio, A. & Wieloch, T., 2010, In: Brain Research. 1321, p. 152-163

  Research output: Contribution to journal › Article › peer-review

  • Apolipoproteins D 100%
  • Clozapine 68%
  • Stroke 40%
  • Infarction 29%
  • Body Weight 16%

• Report of a consensus meeting on human brain temperature after severe traumatic brain injury: Its measurement and management during pyrexia

  Childs, C., Wieloch, T., Lecky, F., Machin, G., Harris, B. & Stocchetti, N., 2010, In: Frontiers in Neurology. NOV, 146.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Traumatic Brain Injury 100%
  • Fever 76%
  • Temperature 72%
  • Brain 49%
  • Body Temperature Regulation 22%

• Rho kinase inhibition protects CA1 cells in organotypic hippocampal slices during in vitro ischemia.

  Gisselsson, L., Toresson, H., Ruscher, K. & Wieloch, T., 2010, In: Brain Research. 1316, p. 92-100

  Research output: Contribution to journal › Article › peer-review

  • rho-Associated Kinases 100%
  • Actins 68%
  • Ischemia 60%
  • Y 27632 37%
  • In Vitro Techniques 35%

• The asparaginyl endopeptidase legumain after experimental stroke.

  Ishizaki, T., Erickson, A., Kuric, E., Shamloo, M., Hara-Nishimura, I., Inacio, A., Wieloch, T. & Ruscher, K., 2010, In: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. Apr 7, p. 1756-1766

  Research output: Contribution to journal › Article › peer-review

  • asparaginylendopeptidase 100%
  • Stroke 40%
  • Infarction 18%
  • Glial Fibrillary Acidic Protein 8%
  • Middle Cerebral Artery Infarction 8%
• 2009

  Enriched environment reduces apolipoprotein E (ApoE) in reactive astrocytes and attenuates inflammation of the peri-infarct tissue after experimental stroke.

  Ruscher, K., Johannesson, E., Brugiere, E., Erickson, A., Rickhag, M. & Wieloch, T., 2009, In: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 29, p. 1796-1805

  Research output: Contribution to journal › Article › peer-review

  • Apolipoproteins E 100%
  • Astrocytes 86%
  • Infarction 78%
  • Stroke 64%
  • Inflammation 55%

• Tumor necrosis factor receptor-1 is essential for LPS-induced sensitization and tolerance to oxygen-glucose deprivation in murine neonatal organotypic hippocampal slices.

  Markus, T., Cronberg, T., Cilio, C., Pronk, C., Wieloch, T. & Ley, D., 2009, In: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 29, p. 73-86

  Research output: Contribution to journal › Article › peer-review

  • Tumor Necrosis Factor Receptors 100%
  • Lipopolysaccharides 74%
  • Oxygen 62%
  • Receptors, Tumor Necrosis Factor, Type I 61%
  • Receptors, Tumor Necrosis Factor, Type II 61%
• 2008

  Apolipoprotein D is elevated in oligodendrocytes in the peri-infarct region after experimental stroke: influence of enriched environment.

  Rickhag, M., Deierborg, T., Patel, S., Ruscher, K. & Wieloch, T., 2008, In: Journal of Cerebral Blood Flow and Metabolism. 28, 3, p. 551-562

  Research output: Contribution to journal › Article › peer-review

  • Apolipoproteins D 100%
  • Oligodendroglia 64%
  • Infarction 49%
  • Stroke 40%
  • Animal Housing 13%

• Intranasal selective brain cooling in pigs

  Covaciu, L., Allers, M., Enblad, P., Lunderquist, A., Wieloch, T. & Rubertsson, S., 2008, In: Resuscitation. 76, 1, p. 83-88

  Research output: Contribution to journal › Article › peer-review

  • Swine 100%
  • Temperature 90%
  • Brain 61%
  • Catheters 49%
  • Hypothermia 43%

• Overexpression of UCP2 protects thalamic neurons following global ischemia in the mouse.

  Deierborg Olsson, T., Wieloch, T., Diano, S., Warden, C. H., Horvath, T. L. & Mattiasson, G., 2008, In: Journal of Cerebral Blood Flow and Metabolism. 28, p. 1186-1195

  Research output: Contribution to journal › Article › peer-review

  • Uncoupling Protein 2 100%
  • Ischemia 51%
  • Neurons 41%
  • Thalamus 20%
  • Dentate Gyrus 14%
• 2007

  Hypothermia Affects Translocation of Numerous Cytoplasmic Proteins Following Global Cerebral Ischemia.

  Teilum, M., Krogh, M., Wieloch, T. & Mattiasson, G., 2007, In: Journal of Proteome Research. 6, 7, p. 2822-2832

  Research output: Contribution to journal › Article › peer-review

  • Hypothermia 100%
  • Hypothermic 97%
  • Brain Ischemia 94%
  • Ischemia 72%
  • Protein Transport 53%

• Rapid and long-term induction of effector immediate early genes (BDNF, Neuritin and Arc) in peri-infarct cortex and dentate gyrus after ischemic injury in rat brain.

  Rickhag, M., Teilum, M. & Wieloch, T., 2007, In: Brain Research. 1151, p. 203-210

  Research output: Contribution to journal › Article › peer-review

  • Immediate-Early Genes 100%
  • Dentate Gyrus 89%
  • Brain-Derived Neurotrophic Factor 86%
  • Cytoskeleton 81%
  • Reperfusion 71%