Research output per year
Research output per year
Research output
- 13 Article
- 13 results
Search results
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2024
Toxic small alarmone synthetase FaRel2 inhibits translation by pyrophosphorylating tRNAGly and tRNAThr
Kurata, T., Takegawa, M., Ohira, T., Syroegin, E. A., Atkinson, G. C., Johansson, M. J. O., Polikanov, Y. S., Garcia-Pino, A., Suzuki, T. & Hauryliuk, V., 2024 Nov 15, In: Science Advances. 10, 46, eadr9624.Research output: Contribution to journal › Article › peer-review
Open Access -
Mechanisms of neutralization of toxSAS from toxin-antitoxin modules
Dominguez-Molina, L., Kurata, T., Cepauskas, A., Echemendia-Blanco, D., Zedek, S., Talavera-Perez, A., Atkinson, G. C., Hauryliuk, V. & Garcia-Pino, A., 2024 Jun 4, (E-pub ahead of print) In: Nature Chemical Biology.Research output: Contribution to journal › Article › peer-review
Open Access -
A virally-encoded tRNA neutralizes the PARIS antiviral defence system
Burman, N., Belukhina, S., Depardieu, F., Wilkinson, R. A., Skutel, M., Santiago-Frangos, A., Graham, A. B., Livenskyi, A., Chechenina, A., Morozova, N., Zahl, T., Henriques, W. S., Buyukyoruk, M., Rouillon, C., Saudemont, B., Shyrokova, L., Kurata, T., Hauryliuk, V., Severinov, K. & Groseille, J. & 7 others, , 2024, In: Nature. 634, 8033, p. 424-431Research output: Contribution to journal › Article › peer-review
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Mechanism of phage sensing and restriction by toxin-antitoxin-chaperone systems
Mets, T., Kurata, T., Ernits, K., Johansson, M. J. O., Craig, S. Z., Evora, G. M., Buttress, J. A., Odai, R., Wallant, K. C., Nakamoto, J. A., Shyrokova, L., Egorov, A. A., Doering, C. R., Brodiazhenko, T., Laub, M. T., Tenson, T., Strahl, H., Martens, C., Harms, A. & Garcia-Pino, A. & 2 others, , 2024, In: Cell Host and Microbe. 32, 7, p. 1059-1073.e8Research output: Contribution to journal › Article › peer-review
Open Access -
2023
The structural basis of hyperpromiscuity in a core combinatorial network of type II toxin-antitoxin and related phage defense systems
Ernits, K., Saha, C. K., Brodiazhenko, T., Chouhan, B., Shenoy, A., Buttress, J. A., Duque-Pedraza, J. J., Bojar, V., Nakamoto, J. A., Kurata, T., Egorov, A. A., Shyrokova, L., Johansson, M. J. O., Mets, T., Rustamova, A., Džigurski, J., Tenson, T., Garcia-Pino, A., Strahl, H. & Elofsson, A. & 2 others, , 2023 Aug 15, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 33, p. 1-12 e2305393120.Research output: Contribution to journal › Article › peer-review
Open Access -
Biochemical and X-ray analyses of the players involved in the faRel2/aTfaRel2 toxin-antitoxin operon
Dominguez-Molina, L., Talavera, A., Cepauskas, A., Kurata, T., Echemendia-Blanco, D., Hauryliuk, V. & Garcia-Pino, A., 2023, In: Acta crystallographica. Section F, Structural biology communications. 79, 10Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Direct activation of a bacterial innate immune system by a viral capsid protein
Zhang, T., Tamman, H., Coppieters 't Wallant, K., Kurata, T., LeRoux, M., Srikant, S., Brodiazhenko, T., Cepauskas, A., Talavera, A., Martens, C., Atkinson, G. C., Hauryliuk, V., Garcia-Pino, A. & Laub, M. T., 2022 Dec 1, In: Nature. 612, 7938, p. 132–140 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
A hyperpromiscuous antitoxin protein domain for the neutralization of diverse toxin domains
Kurata, T., Saha, C. K., Buttress, J. A., Mets, T., Brodiazhenko, T., Turnbull, K. J., Awoyomi, O. F., Oliveira, S. R. A., Jimmy, S., Ernits, K., Delannoy, M., Persson, K., Tenson, T., Strahl, H., Hauryliuk, V. & Atkinson, G. C., 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 6, p. 1-12 e2102212119.Research output: Contribution to journal › Article › peer-review
Open Access -
Clinically observed deletions in SARS-CoV-2 Nsp1 affect its stability and ability to inhibit translation
Kumar, P., Schexnaydre, E., Rafie, K., Kurata, T., Terenin, I., Hauryliuk, V. & Carlson, L.-A., 2022, In: FEBS Letters. 596, 9, p. 1203-1213Research output: Contribution to journal › Article › peer-review
Open Access -
Expression of Bacillus subtilis ABCF antibiotic resistance factor VmlR is regulated by RNA polymerase pausing, transcription attenuation, translation attenuation and (p)ppGpp
Hiraku, T., Mandell, Z. F., Yakhnin, H., Glazyrina, A., Chiba, S., Kurata, T., Wu, K. J. Y., Tresco, B. I. C., Myers, A. G., Atkinson, G., Babitzke, P. & Hauryliuk, V., 2022, In: Nucleic Acids Research. 50, 11, p. 6174-6189 gkac497.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural basis for HflXr-mediated antibiotic resistance in Listeria monocytogenes
Koller, T. O., Turnbull, K. J., Vaitkevicius, K., Crowe-McAuliffe, C., Roghanian, M., Bulvas, O., Nakamoto, J. A., Kurata, T., Julius, C., Atkinson, G. C., Johansson, J., Hauryliuk, V. & Wilson, D. N., 2022, In: Nucleic Acids Research. 50, 19 , p. 11285-11300Research output: Contribution to journal › Article › peer-review
Open Access -
2021
RelA-SpoT Homolog toxins pyrophosphorylate the CCA end of tRNA to inhibit protein synthesis
Kurata, T., Brodiazhenko, T., Alves Oliveira, S. R., Roghanian, M., Sakaguchi, Y., Turnbull, K. J., Bulvas, O., Takada, H., Tamman, H., Ainelo, A., Pohl, R., Rejman, D., Tenson, T., Suzuki, T., Garcia-Pino, A., Atkinson, G. C. & Hauryliuk, V., 2021 Aug 5, In: Molecular Cell. 81, 15, p. 3160-3170. e1-e9Research output: Contribution to journal › Article › peer-review
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2020
A widespread toxin−antitoxin system exploiting growth control via alarmone signaling
Jimmy, S., Saha, C. K., Kurata, T., Stavropoulos, C., Oliveira, S. R. A., Koh, A., Cepauskas, A., Takada, H., Rejman, D., Tenson, T., Strahl, H., Garcia-Pino, A., Hauryliuk, V. & Atkinson, G. C., 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 19, p. 10500-10510Research output: Contribution to journal › Article › peer-review
Open Access