Tom Brown

Tom Brown

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I am a post-doctoral research fellow in the Genetics of Sex Differences (SexGen) research group

Formerly (2017 – 2022), I was a PhD and post-doc at the University of East Anglia (UEA), where my research focused on the ecology and evolution of senescence in wild populations. In particular, I explored whether molecular markers (namely, telomere dynamics and DNA-methylation) can be effective measures of chronological- and biological age, using the Seychelles warbler (Acrocephalus sechellensis) research project as a study system.

The evolution of sex chromosomes is the theme of my current post-doc. Gene copies located on the sex-determining chromosome (the Y-chromosome in mammals or the W-chromosome in birds) are often suppressed, degrade over time, and may even be lost entirely. The sex-chromosomes of songbirds have regions of varying ages (and thus varying states of degradation) making them an excellent system for studying the gene-death process. Specifically, my research will explore the role the DNA-methylation - a mechanism regulating gene expression - in new versus old sex-chromosome regions.    


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