Research output per year
Research output per year
Search results
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2023
LGR5 Expression Predicting Poor Prognosis Is Negatively Correlated with WNT5A in Colon Cancer
Mehdawi, L. M., Ghatak, S., Chakraborty, P., Sjölander, A. & Andersson, T., 2023 Nov, In: Cells. 12, 22, 2658.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Increased MARCKS Activity in BRAF Inhibitor-Resistant Melanoma Cells Is Essential for Their Enhanced Metastatic Behavior Independent of Elevated WNT5A and IL-6 Signaling
Yadav, V., Jobe, N., Satapathy, S. R., Mohapatra, P. & Andersson, T., 2022 Dec, In: Cancers. 14, 24, 6077.Research output: Contribution to journal › Article › peer-review
Open Access -
2021
Targeting Oncogenic WNT Signalling with WNT Signalling-Derived Peptides
Yadav, V., Jobe, N., Mehdawi, L. & Andersson, T., 2021 Aug 29, Handbook of experimental pharmacology. Springer, p. 279-303 (Handbook of experimental pharmacology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Reduced WNT5A signaling in melanoma cells favors an amoeboid mode of invasion
Jobe, N. P., Åsberg, L. & Andersson, T., 2021, In: Molecular Oncology. 15, 7, p. 1835-1848Research output: Contribution to journal › Article › peer-review
Open Access -
2020
WNT5A-induced activation of the protein kinase C substrate MARCKS is required for melanoma cell invasion
Mohapatra, P., Yadav, V., Toftdahl, M. & Andersson, T., 2020 Feb 4, In: Cancers. 12, 2, 346.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Combination therapy targeting the elevated interleukin-6 level reduces invasive migration of BRAF inhibitor-resistant melanoma cells
Mohapatra, P., Prasad, C. P. & Andersson, T., 2019, In: Molecular Oncology. 13, 2, p. 480-494Research output: Contribution to journal › Article › peer-review
Open Access -
The WNT5A Agonist Foxy5 Reduces the Number of Colonic Cancer Stem Cells in a Xenograft Mouse Model of Human Colonic Cancer
Osman, J., Bellamkonda, K., Liu, Q., Andersson, T. & Sjölander, A., 2019, In: Anticancer research. 39, 4, p. 1719-1728 10 p.Research output: Contribution to journal › Article › peer-review
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2018
WNT5A as a therapeutic target in breast cancer
Prasad, C. P., Manchanda, M., Mohapatra, P. & Andersson, T., 2018, In: Cancer and Metastasis Reviews. 37, 4, p. 767-778Research output: Contribution to journal › Review article › peer-review
Open Access -
2017
Reduced production and uptake of lactate are essential for the ability of WNT5A signaling to inhibit breast cancer cell migration and invasion
Prasad, C. P., Södergren, K. & Andersson, T., 2017 Sept 22, In: Oncotarget. 8, 42, p. 71471-71488Research output: Contribution to journal › Article › peer-review
Open Access -
Treatment with the WNT5A-mimicking peptide Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model
Canesin, G., Evans-Axelsson, S., Hellsten, R., Krzyzanowska, A., Prasad, C. P., Bjartell, A. & Andersson, T., 2017 Sept 1, In: PLoS ONE. 12, 9, e0184418.Research output: Contribution to journal › Article › peer-review
Open Access -
Optimization, validation, and identification of two reliable antibodies for immunodetection of WNT5A
Prgomet, Z., Andersson, T. & Lindberg, P., 2017 Feb, In: Biotechnic and Histochemistry. 92, 1, p. 46-58Research output: Contribution to journal › Article › peer-review
Open Access -
Higher expression of WNT5A protein in oral squamous cell carcinoma compared with dysplasia and oral mucosa with a normal appearance
Prgomet, Z., Andersson, T. & Lindberg, P., 2017, In: European Journal of Oral Sciences. 125, 4, p. 237-246Research output: Contribution to journal › Article › peer-review
Open Access -
2016
Non-canonical WNT5A signaling up-regulates the expression of the tumor suppressor 15-PGDH and induces differentiation of colon cancer cells
Mehdawi, L. M., Prasad, C. P., Ehrnström, R., Andersson, T. & Sjölander, A., 2016 Nov 1, In: Molecular Oncology. 10, 9, p. 1415-1429 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Demonstration of a WNT5A-IL-6 positive feedback loop in melanoma cells: Dual interference of this loop more effectively impairs melanoma cell invasion
Linnskog, R., Mohapatra, P., Moradi, F., Prasad, C. P. & Andersson, T., 2016, In: Oncotarget. 7, 25, p. 37790-37802 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Dual mechanisms of action of the RNA-binding protein human antigen R explains its regulatory effect on melanoma cell migration.
Moradi, F., Berglund, P., Linnskog, R., Leandersson, K., Andersson, T. & Prasad, C., 2016, In: Translational Research. 172, p. 45-60Research output: Contribution to journal › Article › peer-review
Open Access -
The STAT3 Inhibitor Galiellalactone Effectively Reduces Tumor Growth and Metastatic Spread in an Orthotopic Xenograft Mouse Model of Prostate Cancer.
Canesin, G., Evans Axelsson, S., Hellsten, R., Sterner, O., Krzyzanowska, A., Andersson, T. & Bjartell, A., 2016, In: European Urology. 69, 3, p. 400-404Research output: Contribution to journal › Article › peer-review
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WNT5A signaling impairs breast cancer cell migration and invasion via mechanisms independent of the epithelial-mesenchymal transition
Prasad, C. P., Chaurasiya, S. K., Guilmain, W. & Andersson, T., 2016, In: Journal of Experimental and Clinical Cancer Research. 35, 1, 144.Research output: Contribution to journal › Article › peer-review
Open Access -
2015
A Wnt5a signaling pathway in the pathogenesis of HIV-1 gp120-induced pain.
Yuan, S., Ji, G., Li, B., Andersson, T., Neugebauer, V. & Tang, S.-J., 2015, In: Pain. 156, 7, p. 1311-1319Research output: Contribution to journal › Article › peer-review
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Migration and invasion of oral squamous carcinoma cells is promoted by WNT5A, a regulator of cancer progression.
Prgomet, Z., Axelsson, L., Lindberg, P. & Andersson, T., 2015, In: Journal of Oral Pathology & Medicine. 44, 10, p. 776-784Research output: Contribution to journal › Article › peer-review
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Therapy for BRAFi-Resistant Melanomas: Is WNT5A the Answer?
Prasad, C., Mohapatra, P. & Andersson, T., 2015, In: Cancers. 7, 3, p. 1900-1924Research output: Contribution to journal › Review article › peer-review
Open Access -
2014
Interleukin-6 drives melanoma cell motility through p38α-MAPK-dependent up-regulation of WNT5A expression.
Linnskog, R., Jönsson, G., Axelsson, L., Prasad, C. & Andersson, T., 2014, In: Molecular Oncology. 8, 8, p. 1365-1378Research output: Contribution to journal › Article › peer-review
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WNT5A induces release of exosomes containing pro-angiogenic and immunosuppressive factors from malignant melanoma cells
Ekström, E., Bergenfelz, C., von Bülow, V., Serifler, F., Carlemalm, E., Jönsson, G. B., Andersson, T. & Leandersson, K., 2014, In: Molecular Cancer. 13, 88.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
WNT5A-mediated β-catenin-independent signalling is a novel regulator of cancer cell metabolism.
Sherwood, V., Chaurasiya, S., Ekström, E., Guilmain, W., Liu, Q., Koeck, T., Brown, K., Hansson, K. M., Agnarsdóttir, M., Bergqvist, M., Jirström, K., Ponten, F., James, P. & Andersson, T., 2014, In: Carcinogenesis. 35, 4, p. 784-794Research output: Contribution to journal › Article › peer-review
Open Access -
2013
WNT-5A triggers Cdc42 activation leading to an ERK1/2 dependent decrease in MMP9 activity and invasive migration of breast cancer cells
Prasad, C. P., Chaurasiya, S. K., Axelsson, L. & Andersson, T., 2013 Oct, In: Molecular Oncology. 7, 5, p. 870-83 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The prognostic significance of wnt-5a expression in primary breast cancer is extended to premenopausal women.
Sand-Dejmek, J., Ehrnström, R., Berglund, P., Andersson, T. & Rydén, L., 2013, In: PLoS ONE. 8, 8, e70890.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2012
Emphasizing the role of Wnt5a protein expression to predict favorable outcome after radical prostatectomy in patients with low-grade prostate cancer
Syed Khaja, A. S., Egevad, L., Helczynski, L., Wiklund, P., Andersson, T. & Bjartell, A., 2012, In: Cancer Medicine. 1, 1, p. 96-104Research output: Contribution to journal › Article › peer-review
File238 Downloads (Pure) -
2011
Cysteinyl leukotriene receptor expression pattern affects migration of breast cancer cells and survival of breast cancer patients.
Magnusson, C., Liu, J., Ehrnström, R., Manjer, J., Jirström, K., Andersson, T. & Sjölander, A., 2011, In: International Journal of Cancer. Okt, p. 9-22Research output: Contribution to journal › Article › peer-review
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Elevated level of wnt5a protein in localized prostate cancer tissue is associated with better outcome.
Syed Khaja, A. S., Helczynski, L., Edsjö, A., Ehrnström, R., Lindgren, A., Ulmert, D., Andersson, T. & Bjartell, A., 2011, In: PLoS ONE. 6, 10, e26539.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Methylation and loss of secreted frizzled-related protein 3 enhances melanoma cell migration and invasion.
Ekström, E., Sherwood, V. & Andersson, T., 2011, In: PLoS ONE. 6, 4, e18674.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
WNT5A Signaling Contributes to A beta-Induced Neuroinflammation and Neurotoxicity
Li, B., Zhong, L., Yang, X., Andersson, T., Huang, M. & Tang, S.-J., 2011, In: PLoS ONE. 6, 8, e22920.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2010
Estrogen receptor alpha is upregulated and metastasis inhibited in a murine breast cancer model following treatment with the novel Wnt-5a derived-hexapeptide, Foxy-5
Ford, C. E., Tuomela, J., Hedditch, E. L., Axelsson, L., Liu, Q., Ward, R. L., Harkonen, P. & Andersson, T., 2010, In: EJC Supplements. 8, 5, p. 43Research output: Contribution to journal › Published meeting abstract › peer-review
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2009
A t-butyloxycarbonyl-modified Wnt5a-derived hexapeptide functions as a potent antagonist of Wnt5a-dependent melanoma cell invasion.
Jenei, V., Sherwood, V., Howlin, J., Linnskog, R., Säfholm, A., Axelsson, L. & Andersson, T., 2009, In: Proceedings of the National Academy of Sciences. 106, 46, p. 19473-19478Research output: Contribution to journal › Article › peer-review
Open Access -
WNT-5a-CKIalpha signaling promotes beta -catenin/E-cadherin complex formation and intercellular adhesion in human breast epithelial cells.
Hagerling, C., Landberg, G., Andersson, T. & Leandersson, K., 2009, In: Journal of Biological Chemistry. 284, p. 10968-10979Research output: Contribution to journal › Article › peer-review
Open Access -
Wnt-5a-induced phosphorylation of DARPP-32 inhibits breast cancer cell migration in a CREB-dependent manner.
Hansen, C., Howlin, J., Tengholm, A., Dyachok, O., Vogel, W. F., Nairn, A. C., Greengard, P. & Andersson, T., 2009, In: Journal of Biological Chemistry. 284, p. 27533-27543Research output: Contribution to journal › Article › peer-review
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2008
beta 2 Integrins target Rap GTPases to the plasma membrane by means of degranulation
Dib, K., Axelsson, L. & Andersson, T., 2008, In: Biochemical and Biophysical Research Communications. 376, 4, p. 642-646Research output: Contribution to journal › Article › peer-review
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Dietary supplementation with carbonate increases expression of ornithine decarboxylase and proliferation in gastric mucosa in a rat model of gastric cancer.
Ehrnström, R., Bjursten, L. M., Ljungberg, O., Veress, B., Haglund, M. E., Lindstrom, C. G. & Andersson, T., 2008, In: International Journal of Cancer. 122, p. 727-733Research output: Contribution to journal › Article › peer-review
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The Wnt-5a-derived hexapeptide Foxy-5 inhibits breast cancer metastasis in vivo by targeting cell motility.
Säfholm, A., Tuomela, J., Rosenkvist, J., Sand-Dejmek, J., Härkönen, P. & Andersson, T., 2008, In: Clinical Cancer Research. 14, 20, p. 6556-6563Research output: Contribution to journal › Article › peer-review
Open Access -
TNK2 preserves epidermal growth factor receptor expression on the cell surface and enhances migration and invasion of human breast cancer cells
Howlin, J., Rosenkvist, J. & Andersson, T., 2008, In: Breast Cancer Research. 10, 2Research output: Contribution to journal › Article › peer-review
Open Access -
2007
Expression and mutation analysis of the discoidin domain receptors 1 and 2 in non-small cell lung carcinoma.
Ford, C., Lau, S. K., Zhu, C. Q., Andersson, T., Tsao, M. S. & Vogel, W. F., 2007, In: British Journal of Cancer. 96, 5, p. 808-814Research output: Contribution to journal › Article › peer-review
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2006
A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells.
Säfholm, A., Leandersson, K., Sand-Dejmek, J., Kamp-Nielsen, C., Villoutreix, B. O. & Andersson, T., 2006, In: Journal of Biological Chemistry. 281, 5, p. 2740-2749Research output: Contribution to journal › Article › peer-review
Open Access -
Dietary supplementation of carbonate promotes spontaneous tumorigenesis in a rat gastric stump model.
Ehrnström, R., Veress, B., Arvidsson, S., Sternby, N., Andersson, T. & Lindstrom, C. G., 2006, In: Scandinavian Journal of Gastroenterology. 41, 1, p. 12-20Research output: Contribution to journal › Article › peer-review
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Nitric oxide produced in response to engagement of beta 2 integrins on human neutrophils activates the monomeric GTPases Rap1 and Rap2 and promotes adhesion
Jenei, V., Deevi, R. K., Adams, C. A., Axelsson, L., Hirst, D. G., Andersson, T. & Dib, K., 2006, In: Journal of Biological Chemistry. 281, 46, p. 35008-35020Research output: Contribution to journal › Article › peer-review
Open Access -
Phosphorylation of DARPP-32 regulates breast cancer cell migration downstream of the receptor tyrosine kinase DDR1.
Hansen, C., Greengard, P., Nairn, A. C., Andersson, T. & Vogel, W. F., 2006, In: Experimental Cell Research. 312, 20, p. 4011-4018Research output: Contribution to journal › Article › peer-review
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Wnt-5a/Ca2+-induced NFAT activity is counteracted by Wnt-5a/Yes-Cdc42-casein kinase 1alpha signaling in human mammary epithelial cells.
Sand-Dejmek, J., Säfholm, A., Kamp-Nielsen, C., Andersson, T. & Leandersson, K., 2006, In: Molecular and Cellular Biology. 26, 16, p. 6024-6036Research output: Contribution to journal › Article › peer-review
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Wnt-5a mRNA translation is suppressed by the Elav-like protein HuR in human breast epithelial cells.
Leandersson, K., Riesbeck, K. & Andersson, T., 2006, In: Nucleic Acids Research. 34, 14, p. 3988-3999Research output: Contribution to journal › Article › peer-review
Open Access -
2005
Critical role for complement receptor 3 (CD11b/CD18), but not for Fc receptors, in killing of Streptococcus pyogenes by neutrophils in human immune serum.
Nilsson, M. E., Weineisen, M., Andersson, T., Truedsson, L. & Sjöbring, U., 2005, In: European Journal of Immunology. 35, 5, p. 1472-1481 10 p.Research output: Contribution to journal › Article › peer-review
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E3B1, a human homologue of the mouse gene product Abi-1, sensitizes activation of Rap1 in response to epidermal growth factor
Jenei, V., Andersson, T., Jakus, J. & Dib, K., 2005, In: Experimental Cell Research. 310, 2, p. 463-473Research output: Contribution to journal › Article › peer-review
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Expression and signaling activity of Wnt-5a/discoidin domain receptor-1 and Syk plays distinct but decisive roles in breast cancer patient survival
Sand-Dejmek, J., Leandersson, K., Manjer, J., Bjartell, A., Emdin, S. O., Vogel, W., Landberg, G. & Andersson, T., 2005, In: Clinical Cancer Research. 11, 2, p. 520-528Research output: Contribution to journal › Article › peer-review
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Protein phosphatase 2A regulates apoptosis in neutrophils by dephosphorylating both p38 MAPK and its substrate caspase 3.
Alvarado-Kristensson, M. & Andersson, T., 2005, In: Journal of Biological Chemistry. 280, 7, p. 6238-6244Research output: Contribution to journal › Article › peer-review
Open Access -
Wnt-5a has tumor suppressor activity in thyroid carcinoma
Kremenevskaja, N., von Wasielewski, R., Rao, A., Schofl, C., Andersson, T. & Brabant, G., 2005, In: Oncogene. 24, 13, p. 2144-2154Research output: Contribution to journal › Article › peer-review