Research output per year
Research output per year
Personal profile
Research
My lab is using a combination of microbiological, biochemical, next-generation sequencing and structural (cryo-EM) approaches to tackle two research directions:
- Molecular mechanisms of bacterial defence against phages
- Protein synthesis on the ribosome: antibiotics, antibiotic resistance, stress sensing and signalling, protein quality control
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Subject classification (UKÄ)
- Microbiology
- Biological Sciences
- Genetics and Genomics
- Structural Biology
- Infectious Medicine
- Immunology
Free keywords
- ribosome
- antibiotic resistance
- antibiotics
- bacteria
- toxin-antitoxin systems
- nucleotide alarmones
- tRNA
- ppGpp
- biochemistry
- molecular microbiology
- cryo-EM
- cats
- learnage
- 70S
- 50S
- 30S
- bacteriophages
- abortive infection
- Swedish summer
- Danish summer
- phages
- antiphage immunity
- Pathogen-associated molecular patterns
- innate immunity
- protein domains
- enzymology
- viruses
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Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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RelA-SpoT Homolog toxins pyrophosphorylate the CCA end of tRNA to inhibit protein synthesis
Kurata, T., Brodiazhenko, T., Alves Oliveira, S. R., Roghanian, M., Sakaguchi, Y., Turnbull, K. J., Bulvas, O., Takada, H., Tamman, H., Ainelo, A., Pohl, R., Rejman, D., Tenson, T., Suzuki, T., Garcia-Pino, A., Atkinson, G. C. & Hauryliuk, V., 2021 Aug 5, In: Molecular Cell. 81, 15, p. 3160-3170. e1-e9Research output: Contribution to journal › Article › peer-review
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(p)ppGpp controls stringent factors by exploiting antagonistic allosteric coupling between catalytic domains
Roghanian, M., Van Nerom, K., Takada, H., Caballero-Montes, J., Tamman, H., Kudrin, P., Talavera, A., Dzhygyr, I., Ekström, S., Atkinson, G. C., Garcia-Pino, A. & Hauryliuk, V., 2021, In: Molecular Cell. 81, 16, p. 3310-3322.e6Research output: Contribution to journal › Article › peer-review
Open Access -
Structural Basis for Bacterial Ribosome-Associated Quality Control by RqcH and RqcP
Crowe-McAuliffe, C., Takada, H., Murina, V., Polte, C., Kasvandik, S., Tenson, T., Ignatova, Z., Atkinson, G. C., Wilson, D. N. & Hauryliuk, V., 2021, In: Molecular Cell. 81, 1, p. 115-126Research output: Contribution to journal › Article › peer-review
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Cyanobacterial Argonautes and Cas4 family nucleases cooperate to interfere with invading DNA
Bobadilla Ugarte, P., Halter, S., Mutte, S. K., Heijstek, C., Niault, T., Terenin, I., Barendse, P., Koopal, B., Roosjen, M., Boeren, S., Hauryliuk, V., Jinek, M., Westphal, A. H. & Swarts, D. C., 2025 Apr 26, (E-pub ahead of print) In: Molecular Cell.Research output: Contribution to journal › Article › peer-review
Open Access -
Antibacterial compounds against non-growing and intracellular bacteria
Kaldalu, N., Bērziņš, N., Berglund Fick, S., Sharma, A., Andersson, N. C., Aedla, J., Hinnu, M., Puhar, A., Hauryliuk, V. & Tenson, T., 2025 Apr 11, In: npj antimicrobials and resistance. 3, 1, 25.Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 5 Active
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A double tap: ribosomal protection though rRNA methylation and antibiotic displacement
Hauryliuk, V. (PI)
2024/12/01 → 2028/12/31
Project: Research
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För banbrytande studier av hur proteinsyntes regleras i bakterier
Hauryliuk, V. (PI)
Göran Gustafssons stiftelse för naturvetenskaplig och medicinsk forskning
2024/04/01 → 2028/12/31
Project: Research
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eSSENCE@LU 10:2 - “New sequence- and structure-based computational methods to find functional domains of proteins
Atkinson, G. (PI), Egorov, A. (Research student), Hauryliuk, V. (Researcher), Bernheim, A. (Researcher), Schwede, T. (Researcher) & Pereira, J. (Researcher)
2024/01/01 → 2025/12/31
Project: Research
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Experimental exploration of bacterial toxin-antitoxin systems
Shyrokova, O. (Researcher), Hauryliuk, V. (Supervisor) & Giske, C. (Assistant supervisor)
2022/06/01 → …
Project: Research
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Decoding bacterial toxin-antitoxin systems: from high-throughput discovery to molecular mechanism and biotechnology
Atkinson, G. (PI), Hauryliuk, V. (Researcher) & Schüler, H. (Researcher)
Knut and Alice Wallenberg Foundation
2021/07/01 → 2026/06/30
Project: Research
Prizes and Distinction
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Göran Gustafssonprisen i molekylär biologi / Göran Gustafsson prize in molecular biology
Hauryliuk, V. (Recipient), 2024 Mar 1
Prize: Prize (including medals and awards)
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The Swedish Fernström Prize
Hauryliuk, V. (Recipient), 2019
Prize: Prize (including medals and awards)
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Science Award of the Estonian Republic
Hauryliuk, V. (Recipient), 2018
Prize: Prize (including medals and awards)
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Ragnar Söderberg Fellow in Medicine
Hauryliuk, V. (Recipient), 2014
Prize: Prize (including medals and awards)