Research output per year
Research output per year
Personal profile
Research
My research focuses on understanding how transposable elements and their epigenetic regulators influence gene expression and therefore contribute to brain aging and the development of related neurodegenerative disorders.
Utilizing human post-mortem brain tissues and direct reprogramming methods, I combine advanced long-read sequencing techniques, such as Oxford Nanopore, with bioinformatics pipelines tailored specifically to study transposons.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Subject classification (UKÄ)
- Medical and Health Sciences
- Basic Medicine
- Neurosciences
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Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Research output
- 5 Article
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DNA methylation governs the sensitivity of repeats to restriction by the HUSH-MORC2 corepressor
Pandiloski, N., Horváth, V., Karlsson, O., Koutounidou, S., Dorazehi, F., Christoforidou, G., Matas-Fuentes, J., Gerdes, P., Garza, R., Jönsson, M. E., Adami, A., Atacho, D. A. M., Johansson, J. G., Englund, E., Kokaia, Z., Jakobsson, J. & Douse, C. H., 2024 Aug 30, In: Nature Communications. 15, 7534.Research output: Contribution to journal › Article › peer-review
Open Access -
Mini-heterochromatin domains constrain the cis-regulatory impact of SVA transposons in human brain development and disease
Horváth, V., Garza, R., Jönsson, M. E., Johansson, P. A., Adami, A., Christoforidou, G., Karlsson, O., Castilla Vallmanya, L., Koutounidou, S., Gerdes, P., Pandiloski, N., Douse, C. H. & Jakobsson, J., 2024, In: Nature Structural & Molecular Biology. 31, 10, p. 1543-1556Research output: Contribution to journal › Article › peer-review
Open AccessFile26 Downloads (Pure) -
LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
Garza, R., Atacho, D. A. M., Adami, A., Gerdes, P., Vinod, M., Hsieh, P., Karlsson, O., Horvath, V., Johansson, P. A., Pandiloski, N., Matas-Fuentes, J., Quaegebeur, A., Kouli, A., Sharma, Y., Jönsson, M. E., Monni, E., Englund, E., Eichler, E. E., Gale Hammell, M. & Barker, R. A. & 3 others, , 2023 Nov 3, In: Science Advances. 9, 44, eadh9543.Research output: Contribution to journal › Article › peer-review
Open Access -
Single-cell transcriptomics of human traumatic brain injury reveals activation of endogenous retroviruses in oligodendroglia
Garza, R., Sharma, Y., Atacho, D. A. M., Thiruvalluvan, A., Abu Hamdeh, S., Jönsson, M. E., Horvath, V., Adami, A., Ingelsson, M., Jern, P., Hammell, M. G., Englund, E., Kirkeby, A., Jakobsson, J. & Marklund, N., 2023, In: Cell Reports. 42, 11, 113395.Research output: Contribution to journal › Article › peer-review
Open Access -
Distinct subcellular autophagy impairments in induced neurons from patients with Huntington's disease
Pircs, K., Drouin-Ouellet, J., Horváth, V., Gil, J., Rezeli, M., Garza, R., Grassi, D. A., Sharma, Y., St-Amour, I., Harris, K., Jönsson, M. E., Johansson, P. A., Vuono, R., Fazal, S. V., Stoker, T., Hersbach, B. A., Sharma, K., Lagerwall, J., Lagerström, S. & Storm, P. & 5 others, , 2022, In: Brain : a journal of neurology. 145, 9, p. 3035-3057Research output: Contribution to journal › Article › peer-review
Open Access
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The first steps towards a CRISPR-based therapeutic approach for a devastating neurodegenerative disorder
Horvath, V. (PI)
2024/06/18 → 2026/06/30
Project: Research
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SVA-mediated chromatin re-organization in XDP
Jakobsson, J. (PI) & Horvath, V. (Researcher)
The Collaborative Center for X-Linked Dystonia-Parkinsonism (CCXDP)
2021/07/01 → …
Project: Research
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Exploring the neuron-specific molecular characteristics of a rare neurodegenerative disorder
Horvath, V. (PI)
The Royal Physiographic Society in Lund
2024/04/15 → 2025/04/30
Project: Research
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Exploring the neuron-specific characteristics of a rare neurodegenerative disorder using a unique patient specific neuronal model
Horvath, V. (Researcher)
The Royal Physiographic Society in Lund
2023/11/15 → 2023/11/30
Project: Research
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Segerfalk Symposium 2024
Jakobsson, J. (Organiser), Douse, C. (Organiser), Horvath, V. (Organiser), Pettersson, P. (Organiser), Pombo, A. (Invited speaker), Bartosovic, M. (Invited speaker), Bayin, N. S. (Invited speaker), Rowe, H. M. (Invited speaker), Toda, T. (Invited speaker), Gerdes, P. (Chair), Dorazehi, F. (Chair), Castilla-Vallmanya, L. (Chair) & Garza, R. (Chair)
2024 May 15Activity: Participating in or organising an event › Organisation of conference
File -
UniStem Day 2024: Dissemination and outreach of stem cell science
Ottosson, D. (Organiser), Magnusson, M. (Organiser), Kidnapillai, S. (Organiser), Ahlenius, H. (Organiser), Luis, A. B. (Organiser), Martinez Curiel, R. (Organiser), Laurin, K. (Organiser), Martos Salvo, P. (Organiser), Das, M. (Contributor), Wendler, M. (Contributor), Sivani, B. M. (Contributor), Ramos Passarello, G. (Contributor), Sozzi, E. (Contributor), García Garrote, M. (Contributor), Harrison Umeano, C. (Contributor), Okeke, U. C. (Contributor), Horvath, V. (Contributor), Garza, R. (Contributor), Adami, A. (Contributor), Castilla-Vallmanya, L. (Contributor), Gerdes, P. (Contributor), Pandiloski, N. (Contributor), Jin, Q. (Contributor), de Guidi, C. (Contributor), Palma Tortosa, S. (Contributor), Fritze, J. (Contributor), Jansson, L. I. (Contributor), Robles Rodriguez, L. (Contributor), Pracucci, E. (Contributor), Shen, Y.-P. (Contributor), Trovato, F. (Contributor), Tampé, J. (Contributor), Thakore, R. (Contributor), Stamouli, C.-A. (Contributor), Pinto dos Santos Vaz, C. (Contributor), Aretio, C. (Contributor), Piochon, C. (Contributor), Cepeda-Prado, E. (Contributor), de Jongh, M.-M. (Contributor), Tsalkitzidou, M. (Contributor), Bonsberger, J. (Contributor), Douse, C. (Contributor), Dorazehi, F. (Contributor), Koutounidou, S. (Contributor), Jarl, U. (Contributor), Corsi, S. (Contributor), Bruzelius, A. (Contributor), Mattsson, B. (Contributor), Hammarberg, A. (Contributor), Habekost, M. (Contributor), Prabhala, P. (Contributor), Bremborg, T. (Contributor), Nair, M. S. (Contributor), Burdeyron, P. (Contributor), Mazariegos, M. (Contributor), Björklund, M. (Contributor), Hidalgo, I. (Contributor), Hägg, A. (Invited speaker), Hammarlund, E. (Invited speaker), Mohlin, S. (Invited speaker) & Oesterle, M. (Contributor)
2024 Mar 22Activity: Participating in or organising an event › Organisation of workshop/ seminar/ course