Research output per year
Research output per year
Personal profile
UKÄ subject classification
- Medical and Health Sciences
- Natural Sciences
- Engineering and Technology
- Agricultural Sciences
Keywords
- Protein
- Yeast
- Neutron
- Protein Expression
- Protein Purification
- Crystallography
- Protein Crystrallography
- Neutron reflectometry
- Neutron diffraction
- Protein Production
- Non-conventional yeast
- Enzymology
- Proteases
- Drug discovery
- Drug design
- X-ray diffraction
- Biodiversity
- Genetics
- Deuteration
- Perdeuteration
- Enzyme
- Enzyme kinetics
- Enzyme assays
- Molecular Biology
- enzyme engineering
- pyrimidines
- pyrimidine biosynthesis
- deoxyribonucleoside kinase
- dihydroorotate dehydrogenase
- Assay development
- carbonic anhydrase
- Gene Therapy
- Cancer and Oncology
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Dive into the research topics where Wolfgang Knecht is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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New Insights into the Interaction of Class II Dihydroorotate Dehydrogenases with Ubiquinone in Lipid Bilayers as a Function of Lipid Composition
Orozco Rodriguez, J. M., Wacklin-Knecht, H. P., Clifton, L. A., Bogojevic, O., Leung, A., Fragneto, G. & Knecht, W., 2022 Feb 23, In: International Journal of Molecular Sciences. 23, 5, 28 p., 2437.Research output: Contribution to journal › Article › peer-review
Open Access -
Protein-lipid interactions of human dihydroorotate dehydrogenase and three mutants associated with Miller syndrome
Orozco Rodriguez, J. M., Wacklin-Knecht, H. & Knecht, W., 2022 Feb 20, (E-pub ahead of print) In: Nucleosides, Nucleotides & Nucleic Acids. p. 1-22Research output: Contribution to journal › Article › peer-review
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Protein production, kinetic and biophysical characterization of three human dihydroorotate dehydrogenase mutants associated with Miller syndrome
Orozco Rodriguez, J. M., Krupinska, E., Wacklin-Knecht, H. & Knecht, W., 2022 Jan 30, (E-pub ahead of print) In: Nucleosides, Nucleotides & Nucleic Acids. p. 1-19Research output: Contribution to journal › Article › peer-review
Open Access -
Identification of fragments binding to SARS-CoV-2 nsp10 reveals ligand-binding sites in conserved interfaces between nsp10 and nsp14/nsp16
Kozielski, F., Sele, C., Talibov, V. O., Lou, J., Dong, D., Wang, Q., Shi, X., Nyblom, M., Rogstam, A., Krojer, T., Fisher, Z. & Knecht, W., 2021 Oct 6, In: RSC Chemical Biology. 3, 1, p. 44-55 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Biophysical Characterization of Cancer-Related Carbonic Anhydrase IX
Koruza, K., Murray, A. B., Mahon, B. P., Hopkins, J. B., Knecht, W., McKenna, R. & Fisher, S. Z., 2020 Jul 25, In: International Journal of Molecular Sciences. 21, 15, 5277.Research output: Contribution to journal › Article › peer-review
Open Access
Projects
- 1 Finished
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FragMAX - a facility for high throughput fragment screening in drug development by X-ray crystallography
Lima, G., Müller, U., Knecht, W., Logan, D., Zawierucha, A., Sjögren, T., Talibov, V., Jagudin, E., Gourdon, M. & Sele, C.
2019/01/19 → 2022/01/18
Project: Research