Research output per year
Research output per year
Personal profile
Subject classification (UKÄ)
- Medical and Health Sciences
- Natural Sciences
- Engineering and Technology
- Agricultural and Veterinary sciences
Free keywords
- Protein
- Yeast
- Neutron
- Protein Expression
- Protein Purification
- Crystallography
- Protein Crystrallography
- Neutron reflectometry
- Neutron diffraction
- Protein Production
- Non-conventional yeast
- Enzymology
- Proteases
- Drug discovery
- Drug design
- X-ray diffraction
- Biodiversity
- Genetics
- Deuteration
- Perdeuteration
- Enzyme
- Enzyme kinetics
- Enzyme assays
- Molecular Biology
- enzyme engineering
- pyrimidines
- pyrimidine biosynthesis
- deoxyribonucleoside kinase
- dihydroorotate dehydrogenase
- Assay development
- carbonic anhydrase
- Gene Therapy
- Cancer and Oncology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 8 Decent Work and Economic Growth -
SDG 9 Industry, Innovation, and Infrastructure -
SDG 12 Responsible Consumption and Production
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Dive into the research topics where Wolfgang Knecht is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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A truncated CDC14A retains catalytic structure and phosphatase activity preserving male fertility but causes nonsyndromic deafness
Shabbir, K., Jackisch, G., Belyantseva, I. A., Imran, M., Naz, S., Sele, C., Murina, V., Knecht, W., Friedman, T. B., Logan, D. T. & Imtiaz, A., 2026, In: The Journal of biological chemistry. 302, 1, 110982.Research output: Contribution to journal › Article › peer-review
Open Access -
Off-target binding of the histone deacetylase inhibitor vorinostat to carbonic anhydrase II and IX
Gulkis, M. C., Hodgkinson, J. T., Sele, C. P., Knecht, W., McKenna, R. & Fisher, S. Z., 2025 Sept 1, In: Acta Crystallographica Section F Structural Biology Communications. 81, 9, p. 388-397Research output: Contribution to journal › Article › peer-review
Open Access -
Structural basis for small molecule binding to the SARS-CoV-2 nsp10–nsp14 ExoN complex
Kozielski, F., Fisher, Z., Ma, S., Al Busaidi, F., Krupinska, E., Nyblom, M., Sele, C., McDuffie Sullivan, H., Krojer, T. & Knecht, W., 2025 Aug 5, In: Nucleic Acids Research. 53, 14, gkaf753.Research output: Contribution to journal › Article › peer-review
Open Access -
FragMAX Facility for Crystallographic Fragment and Ligand Screening at MAX IV
Kanchugal P., S., Jagudin, E., Lima, G. M. A., Talibov, V. O., Begum, A., Nan, J., Eguiraun, M., Gonzalez, A., Sele, C., Nyblom, M., Knecht, W., Logan, D. T., Sjögren, T., Thunnissen, M., Ursby, T., Obiols‐Rabasa, M., Larsson, M., Mueller, U. & Krojer, T., 2025 Feb 1, In: Applied Research. 4, 1, 11 p., e202400263.Research output: Contribution to journal › Article › peer-review
Open Access -
NK-A 17E-233I: a novel competitive inhibitor of human dihydroorotate dehydrogenase (DHODH) for cancer therapy
Anwar, M. M., Meseguer, S., García-Rodríguez, N., Krupinska, E., Sele, C., Rodríguez-Jiménez, A., Verma, S., Sagadevan, S., Ramon, J., Martí, R., Occhipinti, A., Angione, C., Ordóñez-Morán, P., Knecht, W., Huertas, P. & Juanes, M. A., 2025, In: Journal of Experimental & Clinical Cancer Research. 44, 292.Research output: Contribution to journal › Article › peer-review
Open Access
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VIGILANT: Targeting ER Import and Activation of Viral Glycoproteins: Towards Broad-Spectrum Antivirals
Knecht, W. (PI)
European Commission - Horizon Europe
2025/01/01 → 2028/12/31
Project: Research
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FragMAX - a facility for high throughput fragment screening in drug development by X-ray crystallography
Lima, G. (Project coordinator), Müller, U. (Researcher), Knecht, W. (Researcher), Logan, D. (Researcher), Zawierucha, A. (Administrator), Sjögren, T. (Researcher), Talibov, V. (Researcher), Jagudin, E. (Researcher), Gourdon, M. (Researcher) & Sele, C. (Researcher)
2019/01/19 → 2022/01/18
Project: Research