Research output per year
Research output per year
Project Details
Description
The Swedish Better Diabetes Diagnosis (BDD) study has been ongoing for more than ten years and detailed information and blood samples have been collected from more than 7000 children and adolescents with newly diagnosed diabetes. The discrimination between type 1 and type 2 diabetes is improved by means of HLA, diabetes autoantibodies and C-peptide. These analyses are therefore included in the clinical check-up for all children and adolescents in Sweden who are diagnosed with diabetes. Type 1 diabetes is still the most prevalent type of diabetes and Type 2 diabetes is still relatively rare in Sweden. However, it is urgent to obtain a correct diagnosis including monogenic diabetes (MODY). Sequencing of MODY genes should be performed if an individual with diabetes is autoantibody negative and have an HLA pattern associated with low risk for type 1 diabetes.
| Acronym | BDD |
|---|---|
| Status | Active |
| Effective start/end date | 2005/05/01 → … |
Collaborative partners
- Lund University (lead)
- Sahlgrenska Academy
- Queen Silvia Children’s Hospital
- Sahlgrenska University Hospital
- Karolinska Institute
- Karolinska University Hospital
- Linköping University
Funding
- Diabetesfonden - Stiftelsen Svenska Diabetesförbundets Forskningsfond
- Barndiabetesfonden
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
UKÄ subject classification
- Endocrinology and Diabetes
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Childhood screening for type 1 diabetes comparing automated multiplex Antibody Detection by Agglutination-PCR (ADAP) with single plex islet autoantibody radiobinding assays
Lind, A., Freyhult, E., de Jesus Cortez, F., Ramelius, A., Bennet, R., Robinson, P. V., Seftel, D., Gebhart, D., Tandel, D., Maziarz, M., Larsson, H. E., Lundgren, M., Carlsson, A., Nilsson, A.-L., Fex, M., Törn, C., Agardh, D., Tsai, C.-T., Lernmark, Å. & Better Diabetes Diagnosis (BDD) Study Group, 2024, In: EBioMedicine. 104, 105144.Research output: Contribution to journal › Article › peer-review
Open Access -
Month of birth and the risk of developing type 1 diabetes among children in the Swedish national Better Diabetes Diagnosis Study
Hedlund, E., Ludvigsson, J., Elding Larsson, H., Forsander, G., Ivarsson, S., Marcus, C., Samuelsson, U., Persson, M. & Carlsson, A., 2022, In: Acta Paediatrica, International Journal of Paediatrics. 111, 12 , p. 2378-2383Research output: Contribution to journal › Article › peer-review
Open Access -
Nine residues in HLA-DQ molecules determine with susceptibility and resistance to type 1 diabetes among young children in Sweden
Zhao, L. P., Papadopoulos, G. K., Moustakas, A. K., Bondinas, G. P., Carlsson, A., Larsson, H. E., Ludvigsson, J., Marcus, C., Persson, M., Samuelsson, U., Wang, R., Pyo, C.-W., Geraghty, D. E. & Lernmark, Å., 2021 Apr 23, In: Scientific Reports. 11, 1, 8821.Research output: Contribution to journal › Article › peer-review
Open Access