Dosimetry in radionuclide therapy

Development and evaluation of methods for semi-automatic segmentation of tissues in nuclear medicinal images acquired during radionuclide therapy or during related diagnostic examinations with determination of absorbed radiation doses to tumours and/or other radiation sensitive structures as the primary application.

Investigation of absorbed doses to tumours in Lu177-PRRT with the above method and investigation of absorbed dose - response relationships.

Characterization of hand held gamma camera with phantom measurements and Monte Carlo simulations.

Development of a computer program that can automatically delineate, with the guidance of a user, tumours and other objects visible in images acquired with an imaging device such as a gamma camera or a PET camera. The delineations and the images are used to determine what doses of radiation that tumours and other organs recieve during cancer treatment in radionuclide therapy.

This method is applied on a specific type of radionuclide therapy and absorbed radiation doses to tumours are studied. A possible relationship between the absorbed doses to tumours and the effect of the treatment is investigated.

A small light weight gamma camera that is characterized by using it to take images of devices made specifically for the evaluation of various properties of gamma cameras.