Project Details
Description
The purpose of this project is to develop novel MRI-based biomarkers for prostate cancer detection and diagnosis, and to link the proposed biomarkers to features of the prostate tissue microstructure.
Our aims are to:
I. Develop a data-driven analysis tools of prostate tissue microstructure based on multidimensional MRI to produce salient parameters and biomarker candidates.
II. Perform a longitudinal multidimensional MRI study of mice implanted with human prostate cancer that undergo external radiotherapy. Dissect cancer tissue for Aim III.
III. Develop analysis software to establish link between multidimensional MRI signal/biomarkers and the underlying cancer histology (3D) and immunohistochemistry (2D).
Our aims are to:
I. Develop a data-driven analysis tools of prostate tissue microstructure based on multidimensional MRI to produce salient parameters and biomarker candidates.
II. Perform a longitudinal multidimensional MRI study of mice implanted with human prostate cancer that undergo external radiotherapy. Dissect cancer tissue for Aim III.
III. Develop analysis software to establish link between multidimensional MRI signal/biomarkers and the underlying cancer histology (3D) and immunohistochemistry (2D).
| Short title | eSSENCE@LU 9:2 |
|---|---|
| Status | Active |
| Effective start/end date | 2023/01/01 → 2026/12/31 |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
