Research output per year
Research output per year
Project Details
Description
My PhD project concerns the structure and function of SMIM1, a newly discovered eryhtroid protein. We know that a desrupted SMIM1 gene gives rise to the rare blood group pheonotype Vel-negative (Vel-) but we do not know the function of SMIM1, or the consequences, if any, for people who lack it. I focus on the biochemical characteristics of SMIM1 and its relationship to the Vel blood group antigen. I also investigate the role of SMIM1 in eryhtropoesis in vitro.
Layman's description
My PhD project concerns the structure and function of SMIM1, a newly discobered protein with connection to the blood group Vel.
| Short title | Investigation into erythroid protein SMIM1 |
|---|---|
| Status | Active |
| Effective start/end date | 2016/05/01 → … |
Research output
- 2 Article
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Dimerization of small integral membrane protein 1 promotes cell surface presentation of the Vel blood group epitope
Kelley, L. P., Nylander, A., Arnaud, L., Schmoker, A. M., St. Clair, R. M., Gleason, L. A., Souza, J. M., Storry, J. R., Olsson, M. L. & Ballif, B. A., 2020 Apr, In: FEBS Letters. 594, 8, p. 1261-1270 10 p.Research output: Contribution to journal › Article › peer-review
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SMIM1, carrier of the Vel blood group, is a tail-anchored transmembrane protein and readily forms homodimers in a cell-free system
Nylander, A., Leznicki, P., Vidovic, K., High, S. & Olsson, M. L., 2020, In: Bioscience Reports. 40, 5, BSR20200318.Research output: Contribution to journal › Article › peer-review
Open Access