Routine genetic testing for defective mismatch repair (dMMR) in new cases of colorectal cancer, together with genetic analysis of the patient's relatives serve to identify persons with Lynch's syndrome (LS). Persons with LS have elevated risks of colorectal and other cancers. Identification and follow-up of persons with LS is expected to result in changed treatment, prevented cancer cases and gained lifeyears. Testing and follow-up will increase costs, however prevention of cancer will result in cost reduction. We study the health economic consequences of implementing routine testing for dMMR, genetic analysis and follow-up, in the Southern Swedish healthcare region.
|Effective start/end date||2017/12/01 → …|