Project Details
Description
Type 2 diabetes (T2D) develops due to dysfunction of endocrine cells in the pancreatic islets of Langerhans, often in combination with insulin resistance in muscle, liver, and adipose tissue. In this project we are using long-read RNA-sequencing of human pancreatic islets from donors with and without T2D to generate gene expression data at single isoform resolution in single cells. This will deepen our knowledge of the different islet cell islet types and identify cellular changes that contribute to T2D.
| Status | Finished |
|---|---|
| Effective start/end date | 2025/01/01 → 2025/12/31 |
Funding
- Dir Albert Påhlssons stiftelse för forskning och välgörenhet
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
Subject classification (UKÄ)
- Cell and Molecular Biology
- Endocrinology and Diabetes