Integrated Continuous Downstream Processes for Next-generation of Biologics

Integrated continuous downstream processes are considered to be an important part of the next generation production systems for new biologics. Integrated continuous downstream processes have higher productivity and smaller foot print compared to existing processes. the introdution of a new processeing paradigm in the biopharamaceutical idustry required methods and tools ofr process development and verification in all stages in the drug cadidate development. This proposal will add design and control tools for increased flexibility and controllability of the process at development in both preclinical stage and in clinical studies.