Project Details
Description
The dissertation deals with identifying the mechanisms of dexamethasone resistance in B-ALL and venetoclax resistance in T-ALL. We have also identified mono or combination therapies to overcome this resistance.
Popular science description
Acute lymphoblastic leukemia comprises both B-ALL and T-ALL. The dissertation deals with identifying the mechanisms of resistance to a glucocorticoid, dexamethasone in B-ALL and a BCL2 inhibitor, venetoclax in T-ALL. We have also identified mono or combination therapies to overcome this resistance.
| Status | Finished |
|---|---|
| Effective start/end date | 2017/08/01 → 2021/10/31 |
UKÄ subject classification
- Cell and Molecular Biology
- Other Basic Medicine