Paving the way for anti-inflammatory treatments in Moyamoya disease

Project: Other

Project Details

Description

1. To test if MRTFs act in synergy with NOTCH to promote NO-signaling.
2. To examine if the MRTF-SRF target gene NEXN counteracts aneurysm-formation.
3. To address if MRTF-SRF signaling regulates focal adhesions and vascular disease in vivo.
4. To examine whether MRTFs regulate plaque stability via MBNL1-AS1.
StatusFinished
Effective start/end date2018/11/232019/11/30

Funding

  • Alfred Österlunds stiftelse