sustainable exploitation of biobased compounds revealed and engineered from natural resources

https://www.secreted.eu/

The SECRETed project will fully exploit the potential of Systems and Synthetic Biology toolboxes and their application within aquatic biotechnology to develop novel hybrid compounds for the agrochemical, pharmaceutical, cosmetic and chemistry sectors. Biosynthetic pathways of marine and extremophilic microorganisms will be reverse engineered to infer the individual roles of their constituent genes, which will be further combined for the production of non-natural biosurfactants and siderophores with tailor-made properties. Biosurfactants are compounds with surface-active nature tendency to adsorb at interfaces, while siderophores have the ability to chelate and transport Fe3+ ions. An iterative procedure following the Design-Build-Test-Learn methodological steps will be used to produce new microbial strains that support the selected genetic elements and satisfy sustainable industrial processing solutions for the production of biosurfactants and siderophores.