Research output per year
Research output per year
Project Details
Description
The T2 distribution in brain is fitted to multi-echo 3D GraSE (gradient and spin echo) data acquired at 7T. The short T2 components (around 15ms) are assigned to "myelin water" entrapped in the multiple bilayers of myelin. The high signal to noise ratio at 7T is employed for increased resolution and additional acceleration compared to 3T.
| Short title | 7Tmyelin imaging |
|---|---|
| Status | Finished |
| Effective start/end date | 2017/07/04 → 2018/03/31 |
Collaborative partners
- Lund University (lead)
- University of British Columbia
Free keywords
- myelin
- MRI
- Ultra-high-field
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In vivo investigation of the multi‐exponential T2 decay in human white matter at 7 T: Implications for myelin water imaging at UHF
Wiggermann, V., MacKay, A. L., Rauscher, A. & Helms, G., 2021, In: NMR in Biomedicine. 34, 2, e4429.Research output: Contribution to journal › Article › peer-review
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Non-negative least squares computation for in vivo myelin mapping using simulated multi-echo spin-echo T2 decay data
Wiggermann, V., Kolind, S. L., Vavasour, I. M., MacKay, A. L., Helms, G. & Rauscher, A., 2020 Dec, In: NMR in Biomedicine. 33, 12, e4277.Research output: Contribution to journal › Article › peer-review
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Non-negative least squares fitting of multi-exponential T2 decay data: Are we able to accurately measure the fraction of myelin water?
Wiggermann, V., Vavasour, I. M., Hernandez-Torres, E., Helms, G., MacKay, A. L. & Rauscher, A., 2019 Apr 26, Non-negative least squares fitting of multi-exponential T2 decay data: Are we able to accurately measure the fraction of myelin water?. Berkeley: International Society for Magnetic Resonance in Medicine, Vol. 27. 4402. (Proc Intl Soc Magn Reson Med; vol. 27).Research output: Chapter in Book/Report/Conference proceeding › Paper in conference proceeding › peer-review
Open AccessFile152 Downloads (Pure)
Infrastructure
Activities
- 2 Presentation
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Toward whole brain mapping of structure-related MRI parameters at ultra-high field strengths using multiple gradient and spin echo read-out and variable flip angles
Helms, G. (Presenter), Olsson, H. (Contributor), Wiggermann, V. (Contributor) & Rauscher, A. (Contributor)
2019 Jul 9Activity: Talk or presentation › Presentation
File -
Multicomponent T2 in brain measured by 3D multi-echo GraSE at 7T
Helms, G. (Speaker)
2018 Oct 1Activity: Talk or presentation › Presentation