Young patients with Stroke in Skane

The aim of the project is to clarify the causes of stroke in individuals younger than 56 years at their first storke episode, where genetic factors may play a greater role than traditional risk factors. Through the database Young Stroke Patients in Skåne, established in 2020, clinical, radiological, and familial data are collected. Whole-genome sequencing of patients, and when appropriate their relatives, is performed to identify monogenic causes. Genetic findings are interpreted alongside detailed clinical information to improve diagnostic accuracy. The study investigates how often a genetic diagnosis can be established and how this may influence treatment and follow-up. The results are expected to enhance etiological understanding, clinical management, and the use of whole-genome sequencing in young stroke patients.