A cubic DNA nanocage probe for in situ analysis of miRNA-10b in tumor-derived extracellular vesicles

Xiaoyan Sun; Yafei Chen; Haiyan Li; Wei Xing; Mingli Chen; Jianhua Wang; Lei Ye

doi:10.1039/d4cc01049c

A cubic DNA nanocage probe for in situ analysis of miRNA-10b in tumor-derived extracellular vesicles

Xiaoyan Sun, Yafei Chen, Haiyan Li, Wei Xing, Mingli Chen, Jianhua Wang, Lei Ye

Northeastern University

Research output: Contribution to journal › Article › peer-review

Abstract

A cubic DNA nanocage probe is able to enter EVs derived from MDA-MB-231 cells and react with miRNA-10b. The probe-loaded EVs were employed to monitor the process of entry of miRNA-10b into MCF-10A cells, allowing visualization of EV-mediated intercellular communication of miRNA-10b between the cancer cells.

Original language	English
Pages (from-to)	4777-4780
Number of pages	4
Journal	Chemical Communications
Volume	60
DOIs	https://doi.org/10.1039/d4cc01049c
Publication status	Published - 2024

Subject classification (UKÄ)

Analytical Chemistry
Medical Laboratory Technologies
Nano-technology

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10.1039/d4cc01049c

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title = "A cubic DNA nanocage probe for in situ analysis of miRNA-10b in tumor-derived extracellular vesicles",

abstract = "A cubic DNA nanocage probe is able to enter EVs derived from MDA-MB-231 cells and react with miRNA-10b. The probe-loaded EVs were employed to monitor the process of entry of miRNA-10b into MCF-10A cells, allowing visualization of EV-mediated intercellular communication of miRNA-10b between the cancer cells.",

author = "Xiaoyan Sun and Yafei Chen and Haiyan Li and Wei Xing and Mingli Chen and Jianhua Wang and Lei Ye",

year = "2024",

doi = "10.1039/d4cc01049c",

language = "English",

volume = "60",

pages = "4777--4780",

journal = "Chemical Communications",

issn = "1364-548X",

publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - A cubic DNA nanocage probe for in situ analysis of miRNA-10b in tumor-derived extracellular vesicles

AU - Sun, Xiaoyan

AU - Chen, Yafei

AU - Li, Haiyan

AU - Xing, Wei

AU - Chen, Mingli

AU - Wang, Jianhua

AU - Ye, Lei

PY - 2024

Y1 - 2024

N2 - A cubic DNA nanocage probe is able to enter EVs derived from MDA-MB-231 cells and react with miRNA-10b. The probe-loaded EVs were employed to monitor the process of entry of miRNA-10b into MCF-10A cells, allowing visualization of EV-mediated intercellular communication of miRNA-10b between the cancer cells.

AB - A cubic DNA nanocage probe is able to enter EVs derived from MDA-MB-231 cells and react with miRNA-10b. The probe-loaded EVs were employed to monitor the process of entry of miRNA-10b into MCF-10A cells, allowing visualization of EV-mediated intercellular communication of miRNA-10b between the cancer cells.

U2 - 10.1039/d4cc01049c

DO - 10.1039/d4cc01049c

M3 - Article

C2 - 38597795

SN - 1364-548X

VL - 60

SP - 4777

EP - 4780

JO - Chemical Communications

JF - Chemical Communications

ER -

A cubic DNA nanocage probe for in situ analysis of miRNA-10b in tumor-derived extracellular vesicles

Abstract

Subject classification (UKÄ)

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