A DNA Methylation Map of Human Atherosclerosis.

Silvio Zaina, Holger Heyn, F Javier Carmona, Nuray Varol, Sergi Sayols, Enric Condom, José Ramírez-Ruz, Antonio Gomez, Isabel Goncalves, Sebastian Moran, Manel Esteller

Research output: Contribution to journalArticlepeer-review

147 Citations (SciVal)

Abstract

-Epigenetic alterations may contribute to the development of atherosclerosis. In particular, DNA methylation, a reversible and highly regulated DNA modification, could influence disease onset and progression since it functions as an effector for environmental influences, including diet and lifestyle, both of which are risk factors for cardiovascular diseases.
Original languageEnglish
Pages (from-to)692-700
JournalCirculation: Cardiovascular Genetics
Volume7
Issue number5
DOIs
Publication statusPublished - 2014

Subject classification (UKÄ)

  • Cardiac and Cardiovascular Systems

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