A long-term follow-up of clinical response and regional cerebral blood flow changes in depressed patients treated with ECT.

Ake Berggren; Lars Gustafson; Peter Höglund; Aki Johanson

doi:10.1016/j.jad.2014.06.005

A long-term follow-up of clinical response and regional cerebral blood flow changes in depressed patients treated with ECT.

Ake Berggren, Lars Gustafson, Peter Höglund, Aki Johanson

Research output: Contribution to journal › Article › peer-review

Abstract

Depression is the leading cause of disability worldwide and electroconvulsive therapy (ECT) is the most potent therapy. We investigated the clinical response and regional cerebral blood flow changes in depressed in patients treated with (ECT) in a repeated longitudinal study. Method: Forty-nine patients (21 men and 28 women) with a mean age 61 years underwent ECT. Forty-one patients grading improvement after the initial ECT-series (responder group) were compared with eight, grading no improvement (non-responder group). The patients underwent neuropsychiatric ratings, measure of clinical response (defined as≥50% reduction of pre-treatment depression score) and measure of regional cerebral blood flow (rCBF).

Original language	English
Pages (from-to)	235-243
Journal	Journal of Affective Disorders
Volume	167
Issue number	Jun 12
DOIs	https://doi.org/10.1016/j.jad.2014.06.005
Publication status	Published - 2014

Bibliographical note

The information about affiliations in this record was updated in December 2015.
The record was previously connected to the following departments: Department of Psychogeriatrics (013304000), Division of Clinical Chemistry and Pharmacology (013250300)

Subject classification (UKÄ)

Psychiatry

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10.1016/j.jad.2014.06.005

http://www.ncbi.nlm.nih.gov/pubmed/24997226?dopt=Abstract

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title = "A long-term follow-up of clinical response and regional cerebral blood flow changes in depressed patients treated with ECT.",

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AU - Gustafson, Lars

AU - Höglund, Peter

AU - Johanson, Aki

N1 - The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Department of Psychogeriatrics (013304000), Division of Clinical Chemistry and Pharmacology (013250300)

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A long-term follow-up of clinical response and regional cerebral blood flow changes in depressed patients treated with ECT.

Abstract

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