A multi-centre study on quality of life and absenteeism in patients with CRS referred for endoscopic surgery

Pernilla Sahlstrand Johnson, Bodil Ohlsson, Christian von Buchwald, Magnus Jannert, Marianne Ahlner-Elmqvist

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Aims: This study summarises the health-related quality of life (HRQOL) scores and absenteeism caused by sinus problems in patients awaiting surgery with the diagnoses recurrent acute rhinosinusitis (RARS), chronic rhinosinusitis with nasal polyps (CRS+NP) or
CRS without nasal polyps (CRS-NP), in a prospective multi-centre study.
Methodology: Two hundred and seven patients with RARS, CRS+NP or CRS-NP were enrolled. EP3OS definitions of CRS and NP were used. The patients completed the 22 Sinonasal Outcome Test (SNOT-22), the short-form 36-item questionnaire (SF-36), the Hospital Anxiety and Depression Scale (HAD) and a total Visual Analogue Scale (VAS)
regarding rhinosinusitis symptoms.
Results: SNOT-22 and VAS scores indicated severe disease. Comparison of the HRQOL scores in the three rhinosinusitis subgroups showed statistical differences in nine of the SNOT-22 items and in the SF-36 subscale of bodily pain. Mean scores of SF-36 were significantly
lower than that of the normal Swedish population. According to the HAD scores, 28% of the patients had probable or possible anxiety or depression disorder. Fifty-seven percent of the patients reported absenteeism from work due to sinus problems.
Conclusions: RARS, CRS+NP and CRS-NP significantly decrease HRQOL. Some statistically significant differences in HRQOL were found between the three rhinosinusitis subgroups. Absenteeism due to chronic sinus conditions is considerable.
Original languageEnglish
Pages (from-to)420-428
Issue number4
Publication statusPublished - 2011

Subject classification (UKÄ)

  • Otorhinolaryngology

Free keywords

  • Key words: chronic rhinosinusitis
  • nasal polyps
  • recurrent acute rhinosinusitis
  • health-related quality of life
  • absenteeism


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