A national study of health-related quality of life in patients with cancer of the base of the tongue compared to the general population and to patients with tonsillar carcinoma

Malin Berg, Ali Adnan, Anders Högmo, Helena Sjödin, Maria Gebre-Medhin, Göran Laurell, Johan Reizenstein, Lovisa Farnebo, Lena Spaak Norberg, Isak Notstam, Erik Holmberg, Hedda Haugen Cange, Eva Hammerlid, Swedish Head and Neck Cancer Register (SweHNCR)

Research output: Contribution to journalArticlepeer-review

1 Citation (SciVal)

Abstract

Background: This exploratory, registry-based, cross-sectional study aimed to evaluate patients' health-related quality of life (HRQOL) in a subsite of oropharyngeal cancer: cancer of the base of the tongue (CBT). Methods: CBT patients, treated with curative intent, completed the EORTC QLQ-C30 and QLQ-H&N35 questionnaires 15 months after diagnosis. The HRQOL of CBT patients was compared to reference scores from the general population and to that of tonsillar carcinoma patients. Results: The 190 CBT patients scored significantly worse than members of the general population on most scales. CBT patients with human papilloma virus (HPV)-positive tumors had significantly better HRQOL on 8 of 28 scales than HPV-negative patients. Compared to 405 tonsillar carcinoma patients, CBT patients had significantly worse HRQOL on 8 of the 28 scales, the majority local head and neck related problems. Conclusion: One year after treatment, CBT patients' HRQOL was significantly worse in many areas compared to that of the general population and slightly worse than that of tonsillar carcinoma patients.

Original languageEnglish
Pages (from-to)3843-3856
JournalHead and Neck
Volume43
Issue number12
Early online date2021
DOIs
Publication statusPublished - 2021

Subject classification (UKÄ)

  • Cancer and Oncology
  • Nursing

Keywords

  • cancer of the base of the tongue
  • head-and-neck cancer
  • human papillomavirus
  • oropharyngeal cancer
  • quality-of-life

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