A novel, minimally invasive rat model of normothermic cardiopulmonary bypass model without blood priming.

Yaobin Zhu, Donghai Liu, Xiaofeng Li, Aijun Liu, Qiang Wang, Chenhui Qiao, Jing Zhang, Qiuming Liao, Yanbo Zhang

Research output: Contribution to journalArticlepeer-review

Abstract

Cardiopulmonary bypass (CPB) has been shown to be associated with systemic inflammatory response leading to postoperative organ dysfunction. Elucidating the underlying mechanisms and developing protective strategies for the pathophysiological consequences of CPB have been hampered due to the absence of a satisfactory recovery animal model. The purpose of this study was to establish a novel, minimally invasive rat model of normothermic CPB model without blood priming.
Original languageEnglish
Pages (from-to)1541-1544
JournalChinese Medical Journal
Volume127
Issue number8
Publication statusPublished - 2014

Subject classification (UKÄ)

  • Cardiac and Cardiovascular Systems
  • Surgery

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