A Peristaltic Pump Driven Zr-89 Separation Module

Jonathan Siikanen, Mikael Peterson, T. A. Tran, Per Roos, Tomas G Ohlsson, Anders Sandell

Research output: Chapter in Book/Report/Conference proceedingPaper in conference proceedingpeer-review

Abstract

To facilitate the separation of Zr-89 produced in yttrium foils, an automated separation module was designed and assembled. The module separates more than 85% of produced Zr-89 - activity in 3 g foils in less than 90 min. About 10 % remains in the dissolving vial. The quality of the separated Zr-89 activity was investigated for labeling of the HER2-binding monoclonal antibody fragment, trastuzumab-Fab.
Original languageEnglish
Title of host publication14th International Workshop on Targetry and Target Chemistry
PublisherAmerican Institute of Physics (AIP)
Pages206-210
Volume1509
DOIs
Publication statusPublished - 2012
Event14th International Workshop on Targetry and Target Chemistry (WTTC) - Playa del Carmen, Mexico
Duration: 2012 Aug 262012 Aug 29

Publication series

Name
Volume1509
ISSN (Print)1551-7616
ISSN (Electronic)0094-243X

Conference

Conference14th International Workshop on Targetry and Target Chemistry (WTTC)
Country/TerritoryMexico
CityPlaya del Carmen
Period2012/08/262012/08/29

Subject classification (UKÄ)

  • Radiology, Nuclear Medicine and Medical Imaging

Free keywords

  • Zr-89
  • PET
  • Separation Module
  • Automation

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