A personalized approach to the management of VWD

Chai W. Phua, Erik Berntorp

Research output: Contribution to journalArticlepeer-review


The goal of treating Von Willebrand Disease (VWD) is to replace deficient or dysfunctional Von Willebrand Factor (VWF) protein. However, the choice of treatment has to be considered carefully in view of patient factors and the unique properties of replacement products. Tailoring a treatment plan to an individual patient's bleeding challenge is an intricate process. This review describes personalization of treatment selection for desmopressin (DDAVP), VWF replacement concentrates, including the newly available recombinant VWF (rVWF) and prophylaxis as a treatment approach in VWD.

Original languageEnglish
Pages (from-to)590-595
JournalTransfusion and Apheresis Science
Issue number5
Early online date2019 Aug 7
Publication statusPublished - 2019

Subject classification (UKÄ)

  • Hematology


  • Management of von Willebrand Disease
  • Personalization of von Willebrand Disease
  • Personalized approach to von Willebrand Disease
  • Treatment of von Willebrand Disease


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