A personalized approach to the management of VWD

Chai W. Phua; Erik Berntorp

doi:10.1016/j.transci.2019.08.009

A personalized approach to the management of VWD

Chai W. Phua, Erik Berntorp

Clinical Coagulation, Malmö

Research output: Contribution to journal › Article › peer-review

Abstract

The goal of treating Von Willebrand Disease (VWD) is to replace deficient or dysfunctional Von Willebrand Factor (VWF) protein. However, the choice of treatment has to be considered carefully in view of patient factors and the unique properties of replacement products. Tailoring a treatment plan to an individual patient's bleeding challenge is an intricate process. This review describes personalization of treatment selection for desmopressin (DDAVP), VWF replacement concentrates, including the newly available recombinant VWF (rVWF) and prophylaxis as a treatment approach in VWD.

Original language	English
Pages (from-to)	590-595
Journal	Transfusion and Apheresis Science
Volume	58
Issue number	5
Early online date	2019 Aug 7
DOIs	https://doi.org/10.1016/j.transci.2019.08.009
Publication status	Published - 2019

Subject classification (UKÄ)

Hematology

Keywords

Management of von Willebrand Disease
Personalization of von Willebrand Disease
Personalized approach to von Willebrand Disease
Treatment of von Willebrand Disease

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10.1016/j.transci.2019.08.009

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title = "A personalized approach to the management of VWD",

abstract = "The goal of treating Von Willebrand Disease (VWD) is to replace deficient or dysfunctional Von Willebrand Factor (VWF) protein. However, the choice of treatment has to be considered carefully in view of patient factors and the unique properties of replacement products. Tailoring a treatment plan to an individual patient's bleeding challenge is an intricate process. This review describes personalization of treatment selection for desmopressin (DDAVP), VWF replacement concentrates, including the newly available recombinant VWF (rVWF) and prophylaxis as a treatment approach in VWD.",

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AB - The goal of treating Von Willebrand Disease (VWD) is to replace deficient or dysfunctional Von Willebrand Factor (VWF) protein. However, the choice of treatment has to be considered carefully in view of patient factors and the unique properties of replacement products. Tailoring a treatment plan to an individual patient's bleeding challenge is an intricate process. This review describes personalization of treatment selection for desmopressin (DDAVP), VWF replacement concentrates, including the newly available recombinant VWF (rVWF) and prophylaxis as a treatment approach in VWD.

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ER -

A personalized approach to the management of VWD

Abstract

Subject classification (UKÄ)

Keywords

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