Abnormal oral vascular network pattern geometry: A new clinical sign of Down syndrome

G Latini, G Bianciardi, S Parrini, Ricardo Laurini, C De Felice

Research output: Contribution to journalArticlepeer-review

13 Citations (SciVal)

Abstract

Down syndrome is a leading genetic cause of mental retardation. Here, we show high fractal dimensions and Lempel-Ziv complexity and lower minimum path fractal dimension (P <= .0006) for the oral vascular networks of patients (n = 14) and their unaffected parents. This newly recognized sign may provide a useful phenotypical marker for identifying couples potentially at risk for offspring with Down syndrome.
Original languageEnglish
Pages (from-to)132-137
JournalJournal of Pediatrics
Volume148
Issue number1
DOIs
Publication statusPublished - 2006

Subject classification (UKÄ)

  • Obstetrics, Gynecology and Reproductive Medicine

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