Activity Quantification from Planar Images

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Abstract

Planar imaging was for a long time the most-used technique for image-based activity quantification. Owing to its simplicity and speed, the possibility to acquire dynamic image sequences, and to generate whole-body images at a reasonable acquisition time, it is still frequently used in nuclear-medicine imaging. Today, planar imaging is most commonly used for diagnostic examinations with qualitative or semi-quantitative evaluation but is also performed for patients receiving radionuclide therapy. Activity quantification may then be applied to estimate the absorbed doses delivered to organs and tumours. It is well recognized that planar images suffer from the superposition of counts from activity located at different depths in the patient and that generally quantitative SPECT is superior for activity quantification. However, the techniques for planar-based activity quantification preceded and, in parts, formed the basis for the subsequent development of quantification methods from tomographic SPECT images, and these techniques still carry value in terms of understanding the process with which planar image projections are formed. Notably, also when acquisition is made in SPECT mode, the raw image data consist of a set of planar projections. Moreover, planar-based activity quantification is still used, for example, to estimate the total-body absorbed dose, and in combination with SPECT-based activity quantification in so-called hybrid planar/SPECT methods.
Original languageEnglish
Title of host publicationHandbook of Nuclear Medicine and Molecular Imaging for Physicists
Subtitle of host publicationInstrumentation and Imaging Procedures
EditorsMichael Ljungberg
Place of PublicationBoca Raton
PublisherCRC Press
Chapter25
Number of pages15
Volume1
Edition1
ISBN (Electronic)9780429489556
ISBN (Print)9781138593268
Publication statusPublished - 2022 Apr 22

Publication series

NameSeries in Medical Physics and Biomedical Engineering
PublisherCRC Press

Subject classification (UKÄ)

  • Radiology, Nuclear Medicine and Medical Imaging

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