Adhesive Mechanisms of Histone-Induced Neutrophil-Endothelium Interactions in the Muscle Microcirculation.

Johanna Puegge, Yongzhi Wang, Jonas Roller, Su Zhang, Lingtao Luo, Brigitte Vollmar, Henrik Thorlacius

Research output: Contribution to journalArticlepeer-review

Abstract

Extracellular histones released during cell damage have the capacity to cause tissue injury associated with increased leukocyte accumulation. However, the molecular mechanisms regulating histone-induced leukocyte recruitment remain elusive. The objective of this study was to examine the role of adhesion molecules in histone-dependent leukocyte accumulation by use of intravital microscopy of the mouse cremaster microcirculation.
Original languageEnglish
Pages (from-to)19-31
JournalEuropean Surgical Research
Volume56
Issue number1-2
DOIs
Publication statusPublished - 2015

Subject classification (UKÄ)

  • Cell and Molecular Biology

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